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Aliases for C3orf84 Gene

Aliases for C3orf84 Gene

  • Chromosome 3 Open Reading Frame 84 2 3 5

External Ids for C3orf84 Gene

Summaries for C3orf84 Gene

GeneCards Summary for C3orf84 Gene

C3orf84 (Chromosome 3 Open Reading Frame 84) is a Protein Coding gene.

Additional gene information for C3orf84 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C3orf84 Gene

Genomics for C3orf84 Gene

GeneHancer (GH) Regulatory Elements for C3orf84 Gene

Promoters and enhancers for C3orf84 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH03I049191 Promoter 0.7 EPDnew 550.8 +0.3 337 0.1 NR2F1 NR2F2 C3orf84 KLHDC8B
GH03I049217 Enhancer 1.2 Ensembl ENCODE 12.2 -26.5 -26501 2.1 FOXA2 MLX ZNF133 ARID4B DMAP1 ZNF48 GTF3C2 SLC30A9 ATF7 FOS WDR6 AMT RBM5 CCDC36 C3orf84 P4HTM C3orf62 USP4 KLHDC8B CCDC71
GH03I049265 Enhancer 0.7 Ensembl ENCODE 11.5 -74.2 -74150 2.6 PRDM12 ZFP64 ZC3H11A ZNF781 ZNF518A ZNF697 WDR6 QRICH1 AMT RBM5 RBM6 SEMA3F-AS1 NME6 IP6K2 USP19 ATRIP
GH03I049269 Enhancer 0.4 ENCODE 11.2 -78.5 -78475 3.3 ATF2 ZIC2 ENSG00000199546 AMT WDR6 CCDC36 C3orf84 KLHDC8B CCDC71 DAG1 RNA5SP130 LAMB2
GH03I049170 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 0.4 +19.3 19265 5 HDGF PKNOX1 ARID4B SIN3A DMAP1 ZNF2 ZBTB7B ZNF766 ZNF213 E2F8 KLHDC8B WDR6 AMT CCDC36 LAMB2 C3orf62 USP4 QARS C3orf84
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around C3orf84 on UCSC Golden Path with GeneCards custom track

Genomic Locations for C3orf84 Gene

Genomic Locations for C3orf84 Gene
14,643 bases
Minus strand

Genomic View for C3orf84 Gene

Genes around C3orf84 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C3orf84 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C3orf84 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C3orf84 Gene

Proteins for C3orf84 Gene

  • Protein details for C3orf84 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C3orf84
    Protein Accession:

    Protein attributes for C3orf84 Gene

    204 amino acids
    Molecular mass:
    23376 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C3orf84 Gene

Post-translational modifications for C3orf84 Gene

No Post-translational modifications

Other Protein References for C3orf84 Gene

No data available for DME Specific Peptides for C3orf84 Gene

Domains & Families for C3orf84 Gene

Gene Families for C3orf84 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for C3orf84 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C3orf84: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C3orf84 Gene

Function for C3orf84 Gene

Phenotypes From GWAS Catalog for C3orf84 Gene

Phenotypes for C3orf84 Gene

GenomeRNAi human phenotypes for C3orf84:
genes like me logo Genes that share phenotypes with C3orf84: view

Animal Model Products

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C3orf84 Gene

Localization for C3orf84 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for C3orf84 Gene

Pathways & Interactions for C3orf84 Gene

SuperPathways for C3orf84 Gene

No Data Available

Interacting Proteins for C3orf84 Gene

Gene Ontology (GO) - Biological Process for C3orf84 Gene


No data available for Pathways by source and SIGNOR curated interactions for C3orf84 Gene

Drugs & Compounds for C3orf84 Gene

No Compound Related Data Available

Transcripts for C3orf84 Gene

mRNA/cDNA for C3orf84 Gene

(4) REFSEQ mRNAs :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for C3orf84 Gene

No ASD Table

Relevant External Links for C3orf84 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C3orf84 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C3orf84 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C3orf84 Gene

This gene is overexpressed in Testis (x51.7).

NURSA nuclear receptor signaling pathways regulating expression of C3orf84 Gene:

genes like me logo Genes that share expression patterns with C3orf84: view

No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C3orf84 Gene

Orthologs for C3orf84 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C3orf84 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia LOC608863 33
  • 89.28 (n)
C3orf84 34
  • 85 (a)
(Bos Taurus)
Mammalia MGC137053 33 34
  • 87.52 (n)
(Mus musculus)
Mammalia BC048562 33 16 34
  • 83.5 (n)
(Rattus norvegicus)
Mammalia LOC680045 33
  • 82.01 (n)
(Monodelphis domestica)
Mammalia C3orf84 34
  • 41 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100485425 33
  • 44.8 (n)
Species where no ortholog for C3orf84 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C3orf84 Gene

Gene Tree for C3orf84 (if available)
Gene Tree for C3orf84 (if available)

Paralogs for C3orf84 Gene

No data available for Paralogs for C3orf84 Gene

Variants for C3orf84 Gene

Sequence variations from dbSNP and Humsavar for C3orf84 Gene

SNP ID Clin Chr 03 pos Variation AA Info Type
rs1000029994 -- 49,179,011(-) G/A/T intron_variant
rs1000630932 -- 49,181,140(-) G/A intron_variant
rs1000747026 -- 49,180,901(-) G/A intron_variant
rs1001088375 -- 49,177,214(-) C/G downstream_transcript_variant
rs1001121893 -- 49,194,542(-) C/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for C3orf84 Gene

Variant ID Type Subtype PubMed ID
esv3596119 CNV loss 21293372
esv3596120 CNV loss 21293372
nsv1008750 CNV gain 25217958
nsv834686 CNV loss 17160897

Variation tolerance for C3orf84 Gene

Residual Variation Intolerance Score: 63.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.75; 15.85% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for C3orf84 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C3orf84 Gene

Disorders for C3orf84 Gene

Additional Disease Information for C3orf84

No disorders were found for C3orf84 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C3orf84 Gene

Publications for C3orf84 Gene

  1. The DNA sequence, annotation and analysis of human chromosome 3. (PMID: 16641997) Muzny DM … Gibbs RA (Nature 2006) 4 58

Products for C3orf84 Gene

Sources for C3orf84 Gene

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