Aliases for C3orf62 Gene
External Ids for C3orf62 Gene
- HGNC: 24771
- Entrez Gene: 375341
- Ensembl: ENSG00000188315
- UniProtKB: Q6ZUJ4
Previous GeneCards Identifiers for C3orf62 Gene
- GC03M049282
Summaries for C3orf62 Gene
GeneCards Summary for C3orf62 Gene
C3orf62 (Chromosome 3 Open Reading Frame 62) is a Protein Coding gene.
Additional gene information for C3orf62 Gene
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C3orf62 Gene
Genomics for C3orf62 Gene
GeneHancer (GH) Regulatory Elements for C3orf62 Gene
Promoters and enhancers for C3orf62 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around C3orf62 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for C3orf62 Gene
Genomic Locations for C3orf62 Gene
- chr3:49,268,597-49,277,909
- (GRCh38/hg38)
- Size:
- 9,313 bases
- Orientation:
- Minus strand
- chr3:49,306,030-49,315,342
- (GRCh37/hg19)
Genomic View for C3orf62 Gene
Genes around C3orf62 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 3p21.31 by Ensembl
- 3p21.31 by Entrez Gene
- 3p21.31 by HGNC
C3orf62 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for C3orf62 Gene
Proteins for C3orf62 Gene
-
Protein details for C3orf62 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q6ZUJ4-CC062_HUMAN
- Recommended name:
- Uncharacterized protein C3orf62
- Protein Accession:
- Q6ZUJ4
- Q6P7E9
- Q7Z3X6
Protein attributes for C3orf62 Gene
- Size:
- 267 amino acids
- Molecular mass:
- 30194 Da
- Quaternary structure:
- No Data Available
Post-translational modifications for C3orf62 Gene
Other Protein References for C3orf62 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for C3orf62
- Invitrogen Antibodies for C3orf62
- GeneTex C3orf62 antibody for C3orf62
Protein Products
-
OriGene Purified Proteins for C3orf62
- Search Origene for MassSpec and Protein Over-expression Lysates for C3orf62
- Origene Custom Protein Services for C3orf62
- Novus Biologicals proteins for C3orf62
- Search GeneTex for Proteins for C3orf62
Assay Products
No data available for DME Specific Peptides for C3orf62 Gene
Domains & Families for C3orf62 Gene
Gene Families for C3orf62 Gene
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Graphical View of Domain Structure for InterPro Entry
No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C3orf62 Gene
Function for C3orf62 Gene
Phenotypes From GWAS Catalog for C3orf62 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 25416956 |
Phenotypes for C3orf62 Gene
- GenomeRNAi human phenotypes for C3orf62:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
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-
-
ViGene Biosciences lentiviral particle packaged cDNA for C3orf62 gene
-
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- Search ViGene Biosciences for C3orf62
CRISPR Products
-
OriGene CRISPR knockouts for C3orf62
- genomics-online: gRNA clones - Search results for 49 available C3orf62 gene related products
- Overview of 49 available C3orf62 gene related products
- Applied Biological Materials CRISPR for C3orf62
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for C3orf62
- GenScript: Design CRISPR guide RNA sequences for C3orf62
miRNA for C3orf62 Gene
- miRTarBase miRNAs that target C3orf62
-
- hsa-mir-3591-5p (MIRT517074)
- hsa-mir-6855-5p (MIRT517075)
- hsa-mir-3170 (MIRT517076)
- hsa-mir-620 (MIRT517077)
- hsa-mir-1270 (MIRT517078)
- hsa-mir-6788-3p (MIRT517079)
- hsa-mir-4460 (MIRT517080)
- hsa-mir-4727-3p (MIRT517081)
- hsa-mir-193b-5p (MIRT517082)
- hsa-mir-4683 (MIRT517083)
- hsa-mir-6890-5p (MIRT517084)
- hsa-mir-1273f (MIRT517085)
- hsa-mir-6849-5p (MIRT517086)
- hsa-mir-3681-5p (MIRT517087)
- hsa-mir-7151-3p (MIRT569593)
- hsa-mir-5095 (MIRT569594)
- hsa-mir-6715b-5p (MIRT569595)
- hsa-mir-4269 (MIRT569596)
- hsa-mir-3622a-5p (MIRT569597)
- hsa-mir-4438 (MIRT569598)
- hsa-mir-6776-3p (MIRT569599)
- hsa-mir-4279 (MIRT624517)
- hsa-mir-6829-3p (MIRT624518)
- hsa-mir-6791-3p (MIRT624519)
- hsa-mir-1976 (MIRT624520)
- hsa-mir-3653-5p (MIRT624521)
- hsa-mir-1914-5p (MIRT624522)
- hsa-mir-6747-3p (MIRT624523)
- hsa-mir-6727-3p (MIRT624524)
- hsa-mir-4722-3p (MIRT624525)
- hsa-mir-660-3p (MIRT624526)
- hsa-mir-5571-5p (MIRT624527)
- hsa-mir-5698 (MIRT693883)
- hsa-mir-744-3p (MIRT693884)
- hsa-mir-4423-5p (MIRT693885)
- hsa-mir-6501-5p (MIRT693886)
- hsa-mir-143-5p (MIRT693887)
- hsa-mir-4430 (MIRT693888)
- hsa-mir-3652 (MIRT693889)
- hsa-mir-122-5p (MIRT693890)
- hsa-mir-504-3p (MIRT693891)
- hsa-mir-3135b (MIRT693892)
- hsa-mir-6499-3p (MIRT693893)
miRNA Products
- Search ViGene Biosciences for C3orf62
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for C3orf62
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- genomics-online: shRNA clones - Search results for 49 available C3orf62 gene related products
- Overview of 49 available C3orf62 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for C3orf62 gene
Clone Products
- VectorBuilder custom plasmid, inducible vectors for C3orf62
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C3orf62
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for C3orf62
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for C3orf62
-
ViGene Biosciences adenoviral particle packaged cDNA for C3orf62 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for C3orf62 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for C3orf62 gene
No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C3orf62 Gene
Localization for C3orf62 Gene
| Compartment | Confidence |
|---|---|
| nucleus | 3 |
| cytosol | 2 |
| extracellular | 1 |
| mitochondrion | 1 |
| endoplasmic reticulum | 1 |
- Nuclear speckles (2)
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C3orf62 Gene
Pathways & Interactions for C3orf62 Gene
No Data Available
Interacting Proteins for C3orf62 Gene
Selected Interacting proteins:
Q6ZUJ4-CC062_HUMAN
ENSP00000341139
for C3orf62 Gene via
IID
UniProtKB
STRING
No data available for Pathways by source and SIGNOR curated interactions for C3orf62 Gene
Transcripts for C3orf62 Gene
mRNA/cDNA for C3orf62 Gene
- (1) REFSEQ mRNAs :
- (7) Additional mRNA sequences :
- (364) Selected AceView cDNA sequences:
- (4) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for C3orf62 Gene
CRISPR Products
-
OriGene CRISPR knockouts for C3orf62
- genomics-online: gRNA clones - Search results for 49 available C3orf62 gene related products
- Overview of 49 available C3orf62 gene related products
- Applied Biological Materials CRISPR for C3orf62
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for C3orf62
- GenScript: Design CRISPR guide RNA sequences for C3orf62
miRNA Products
- Search ViGene Biosciences for C3orf62
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for C3orf62
- Browse OriGene Inhibitory RNA Products For C3orf62
- genomics-online: shRNA clones - Search results for 49 available C3orf62 gene related products
- Overview of 49 available C3orf62 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for C3orf62 gene
Clone Products
- VectorBuilder custom plasmid, inducible vectors for C3orf62
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C3orf62
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for C3orf62
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | ^ | 3 | ^ | 4a | · | 4b | · | 4c |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||||
| SP2: | |||||||||||||||
| SP3: | - |
Expression for C3orf62 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Blood (Hematopoietic System)
- Proerythroblasts Hematopoietic Bone Marrow
- Granulocytes Peripheral Blood
-
Testis (Reproductive System)
- Secondary Spermatocyte Seminiferous Tubules
-
Gonad
- Secondary Spermatocyte Seminiferous Tubules
mRNA differential expression in normal tissues according to GTEx for C3orf62 Gene
This gene is overexpressed in Whole Blood (x8.3).
NURSA nuclear receptor signaling pathways regulating expression of C3orf62 Gene:
C3orf62SOURCE GeneReport for Unigene cluster for C3orf62 Gene:
Hs.403828Primer Products
-
OriGene qPCR primer pairs for C3orf62
-
OriGene qPCR primer pairs and template standards for C3orf62
- genomics-online: primer clones - Search results for 49 available C3orf62 gene related products
- Overview of 49 available C3orf62 gene related products
Gene Expression Assay Products
No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C3orf62 Gene
Orthologs for C3orf62 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | C3H3orf62 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | C20H3orf62 33 |
|
||
| C3orf62 34 |
|
OneToOne | |||
| mouse (Mus musculus) |
Mammalia | 1700102P08Rik 33 16 34 |
|
||
| cow (Bos Taurus) |
Mammalia | C22H3orf62 33 |
|
||
| C3orf62 34 |
|
OneToOne | |||
| rat (Rattus norvegicus) |
Mammalia | LOC498675 33 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | C3orf62 34 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | C3orf62 34 |
|
OneToOne |
- Species where no ortholog for C3orf62 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for C3orf62 Gene
No data available for Paralogs for C3orf62 Gene
Variants for C3orf62 Gene
| SNP ID | Clin | Chr 03 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000050116 | -- | 49,275,429(-) | T/G | intron_variant | |
| rs1000222645 | -- | 49,275,693(-) | G/A | intron_variant | |
| rs1000272501 | -- | 49,268,174(-) | C/T | downstream_transcript_variant | |
| rs1000403796 | -- | 49,275,721(-) | A/AA | intron_variant | |
| rs1000759051 | -- | 49,274,555(-) | C/T | intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv1008750 | CNV | gain | 25217958 |
Residual Variation Intolerance Score:
65.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.64;
65.61% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for C3orf62 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- C3orf62
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C3orf62 Gene
Disorders for C3orf62 Gene
Additional Disease Information for C3orf62
No disorders were found for C3orf62 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C3orf62 Gene
Publications for C3orf62 Gene
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 58
- Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
- The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin EL … Gygi SP (Cell 2015) 3 58
Products for C3orf62 Gene
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- Cyagen custom Knockout/knockin (KOKI) mouse models for C3orf62
- VectorBuilder custom plasmid, inducible vectors for C3orf62
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C3orf62
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- GeneTex C3orf62 antibody for C3orf62
- Search GeneTex for Proteins for C3orf62
- ViGene Biosciences adenoviral particle packaged cDNA for C3orf62 gene
- ViGene Biosciences lentiviral particle packaged cDNA for C3orf62 gene
- ViGene Biosciences ready-to-package AAV shRNAs for C3orf62 gene
- Search ViGene Biosciences for C3orf62
- Horizon Cell Lines for C3orf62
- genomics-online: cdna clones - Search results for 49 available C3orf62 gene related products
- Overview of 49 available C3orf62 gene related products
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- Overview of 49 available C3orf62 gene related products
- genomics-online: gRNA clones - Search results for 49 available C3orf62 gene related products
- Overview of 49 available C3orf62 gene related products
- genomics-online: primer clones - Search results for 49 available C3orf62 gene related products
- Overview of 49 available C3orf62 gene related products
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- Overview of 49 available C3orf62 gene related products
Sources for C3orf62 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems