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Aliases for C3orf62 Gene

Aliases for C3orf62 Gene

  • Chromosome 3 Open Reading Frame 62 2 3 5

External Ids for C3orf62 Gene

Previous GeneCards Identifiers for C3orf62 Gene

  • GC03M049282

Summaries for C3orf62 Gene

GeneCards Summary for C3orf62 Gene

C3orf62 (Chromosome 3 Open Reading Frame 62) is a Protein Coding gene.

Additional gene information for C3orf62 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C3orf62 Gene

Genomics for C3orf62 Gene

GeneHancer (GH) Regulatory Elements for C3orf62 Gene

Promoters and enhancers for C3orf62 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH03I049275 Promoter/Enhancer 1.7 EPDnew Ensembl ENCODE 550.8 +0.0 23 4.4 BACH1 MAX EBF1 RAD21 YY1 POLR2A NFATC1 BCLAF1 IKZF2 RUNX3 C3orf62 WDR6 AMT MST1 MIR4271 USP4
GH03I049338 Promoter/Enhancer 2.7 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 10.9 -68.1 -68141 14.7 MLX ZFP64 DMAP1 IRF4 YY1 SLC30A9 ZNF143 SP3 NFYC ZC3H11A USP4 AMT QRICH1 ENSG00000235236 RBM6 ATRIP RBM5 WDR6 IP6K2 ENSG00000230454
GH03I049409 Promoter/Enhancer 2.5 EPDnew Ensembl ENCODE dbSUPER 10.4 -135.9 -135898 8.9 HDGF PKNOX1 FOXA2 SMAD1 ARNT ARID4B SIN3A DMAP1 YY1 SLC30A9 TCTA RHOA AMT CCDC71 WDR6 SEMA3F-AS1 QRICH1 FAM212A RBM5 DAG1
GH03I049170 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 11.3 +105.0 104993 5 HDGF PKNOX1 ARID4B SIN3A DMAP1 ZNF2 ZBTB7B ZNF766 ZNF213 E2F8 KLHDC8B WDR6 AMT CCDC36 LAMB2 C3orf62 USP4 QARS C3orf84
GH03I049248 Enhancer 1.2 FANTOM5 Ensembl ENCODE 11.7 +29.0 28979 1.5 ATF1 SMAD1 JUN MAX CEBPG EGR1 ATF7 CREM HLF CEBPB AMT WDR6 USP4 C3orf62 LAMB2 KLHDC8B CCDC71 DALRD3 RHOA ARIH2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around C3orf62 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the C3orf62 gene promoter:

Genomic Locations for C3orf62 Gene

Genomic Locations for C3orf62 Gene
chr3:49,268,597-49,277,909
(GRCh38/hg38)
Size:
9,313 bases
Orientation:
Minus strand
chr3:49,306,030-49,315,342
(GRCh37/hg19)

Genomic View for C3orf62 Gene

Genes around C3orf62 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C3orf62 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C3orf62 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C3orf62 Gene

Proteins for C3orf62 Gene

  • Protein details for C3orf62 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZUJ4-CC062_HUMAN
    Recommended name:
    Uncharacterized protein C3orf62
    Protein Accession:
    Q6ZUJ4
    Secondary Accessions:
    • Q6P7E9
    • Q7Z3X6

    Protein attributes for C3orf62 Gene

    Size:
    267 amino acids
    Molecular mass:
    30194 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C3orf62 Gene

Post-translational modifications for C3orf62 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C3orf62 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C3orf62 Gene

Domains & Families for C3orf62 Gene

Gene Families for C3orf62 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for C3orf62 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C3orf62: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C3orf62 Gene

Function for C3orf62 Gene

Phenotypes From GWAS Catalog for C3orf62 Gene

Gene Ontology (GO) - Molecular Function for C3orf62 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with C3orf62: view

Phenotypes for C3orf62 Gene

genes like me logo Genes that share phenotypes with C3orf62: view

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C3orf62 Gene

Localization for C3orf62 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C3orf62 gene
Compartment Confidence
nucleus 3
cytosol 2
extracellular 1
mitochondrion 1
endoplasmic reticulum 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nuclear speckles (2)
See all subcellular structures

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C3orf62 Gene

Pathways & Interactions for C3orf62 Gene

SuperPathways for C3orf62 Gene

No Data Available

Gene Ontology (GO) - Biological Process for C3orf62 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C3orf62 Gene

Drugs & Compounds for C3orf62 Gene

No Compound Related Data Available

Transcripts for C3orf62 Gene

Unigene Clusters for C3orf62 Gene

Chromosome 3 open reading frame 62:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for C3orf62 Gene

ExUns: 1 ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b · 4c
SP1: -
SP2:
SP3: -

Relevant External Links for C3orf62 Gene

GeneLoc Exon Structure for
C3orf62
ECgene alternative splicing isoforms for
C3orf62

Expression for C3orf62 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C3orf62 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C3orf62 Gene

This gene is overexpressed in Whole Blood (x8.3).

NURSA nuclear receptor signaling pathways regulating expression of C3orf62 Gene:

C3orf62

SOURCE GeneReport for Unigene cluster for C3orf62 Gene:

Hs.403828
genes like me logo Genes that share expression patterns with C3orf62: view

No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C3orf62 Gene

Orthologs for C3orf62 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C3orf62 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C3H3orf62 33 34
  • 99.13 (n)
dog
(Canis familiaris)
Mammalia C20H3orf62 33
  • 86.02 (n)
C3orf62 34
  • 74 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 1700102P08Rik 33 16 34
  • 84.86 (n)
cow
(Bos Taurus)
Mammalia C22H3orf62 33
  • 84.44 (n)
C3orf62 34
  • 82 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC498675 33
  • 83.67 (n)
oppossum
(Monodelphis domestica)
Mammalia C3orf62 34
  • 66 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C3orf62 34
  • 31 (a)
OneToOne
Species where no ortholog for C3orf62 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C3orf62 Gene

ENSEMBL:
Gene Tree for C3orf62 (if available)
TreeFam:
Gene Tree for C3orf62 (if available)

Paralogs for C3orf62 Gene

No data available for Paralogs for C3orf62 Gene

Variants for C3orf62 Gene

Sequence variations from dbSNP and Humsavar for C3orf62 Gene

SNP ID Clin Chr 03 pos Variation AA Info Type
rs1000050116 -- 49,275,429(-) T/G intron_variant
rs1000222645 -- 49,275,693(-) G/A intron_variant
rs1000272501 -- 49,268,174(-) C/T downstream_transcript_variant
rs1000403796 -- 49,275,721(-) A/AA intron_variant
rs1000759051 -- 49,274,555(-) C/T intron_variant

Structural Variations from Database of Genomic Variants (DGV) for C3orf62 Gene

Variant ID Type Subtype PubMed ID
nsv1008750 CNV gain 25217958

Variation tolerance for C3orf62 Gene

Residual Variation Intolerance Score: 65.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.64; 65.61% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for C3orf62 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C3orf62

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C3orf62 Gene

Disorders for C3orf62 Gene

Additional Disease Information for C3orf62

No disorders were found for C3orf62 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C3orf62 Gene

Publications for C3orf62 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 58
  4. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  5. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin EL … Gygi SP (Cell 2015) 3 58

Products for C3orf62 Gene

Sources for C3orf62 Gene

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