Aliases for C3AR1 Gene
External Ids for C3AR1 Gene
Previous GeneCards Identifiers for C3AR1 Gene
C3a is an anaphylatoxin released during activation of the complement system. The protein encoded by this gene is an orphan G protein-coupled receptor for C3a. Binding of C3a by the encoded receptor activates chemotaxis, granule enzyme release, superoxide anion production, and bacterial opsonization. [provided by RefSeq, May 2016]
GeneCards Summary for C3AR1 Gene
C3AR1 (Complement C3a Receptor 1) is a Protein Coding gene. Diseases associated with C3AR1 include Complement Component 3 Deficiency and Complement Component 5 Deficiency. Among its related pathways are Signaling by GPCR and A-beta Uptake and Degradation. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and complement component C3a receptor activity. An important paralog of this gene is CMKLR1.
UniProtKB/Swiss-Prot Summary for C3AR1 Gene
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.