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Aliases for C20orf144 Gene

Aliases for C20orf144 Gene

  • Chromosome 20 Open Reading Frame 144 2 3 5
  • Bcl-2-Like Protein From Testis 2 3 4
  • Bclt 3 4
  • Uncharacterized Protein C20orf144 3
  • DJ63M2.6 3

External Ids for C20orf144 Gene

Previous GeneCards Identifiers for C20orf144 Gene

  • GC20P032008
  • GC20P032918
  • GC20P032965
  • GC20P031713
  • GC20P032250
  • GC20P029036

Summaries for C20orf144 Gene

GeneCards Summary for C20orf144 Gene

C20orf144 (Chromosome 20 Open Reading Frame 144) is a Protein Coding gene.

Additional gene information for C20orf144 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C20orf144 Gene

Genomics for C20orf144 Gene

GeneHancer (GH) Regulatory Elements for C20orf144 Gene

Promoters and enhancers for C20orf144 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH20I033662 Promoter/Enhancer 1.5 Ensembl ENCODE 550.8 +1.4 1440 2.2 HDGF MLX ARID4B SIN3A DMAP1 ZNF2 POLR2B E2F8 ZNF207 ZNF143 C20orf144 ENSG00000272945 NECAB3 ASIP ACTL10
GH20I033663 Promoter 0.6 EPDnew 550.8 +0.0 24 0.1 POLR2A C20orf144 ACTL10 NECAB3
GH20I033561 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE dbSUPER 11 -99.9 -99934 1.2 ATF1 FOXA2 ARID4B DMAP1 ZNF2 ZNF48 YY1 TCF12 SLC30A9 ATF7 CBFA2T2 GC20P033562 C20orf144 ACTL10 NECAB3 PXMP4 ZNF341 ENSG00000229188 GC20P033491 GC20P033492
GH20I033553 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 10.9 -107.3 -107340 3.1 HDGF PKNOX1 FOXA2 MLX ZNF48 YY1 ATF7 RXRA NFYC MIER2 CBFA2T2 C20orf144 ACTL10 NECAB3 PXMP4 ENSG00000229188 ZNF341 CDK5RAP1 CHMP4B BPIFB4
GH20I033567 Enhancer 1.2 Ensembl ENCODE dbSUPER 11 -92.8 -92838 3.4 PKNOX1 FOXA2 SIN3A RAD21 RARA ETS1 SCRT2 RCOR1 RUNX3 THAP11 CBFA2T2 C20orf144 ACTL10 NECAB3 SNTA1 E2F1 GC20P033562 GC20M033592
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around C20orf144 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the C20orf144 gene promoter:

Genomic Locations for C20orf144 Gene

Genomic Locations for C20orf144 Gene
chr20:33,662,284-33,665,619
(GRCh38/hg38)
Size:
3,336 bases
Orientation:
Plus strand
chr20:32,250,090-32,253,425
(GRCh37/hg19)

Genomic View for C20orf144 Gene

Genes around C20orf144 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C20orf144 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C20orf144 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C20orf144 Gene

Proteins for C20orf144 Gene

  • Protein details for C20orf144 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BQM9-CT144_HUMAN
    Recommended name:
    Uncharacterized protein C20orf144
    Protein Accession:
    Q9BQM9
    Secondary Accessions:
    • Q1AHR2

    Protein attributes for C20orf144 Gene

    Size:
    153 amino acids
    Molecular mass:
    17214 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C20orf144 Gene

Post-translational modifications for C20orf144 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C20orf144 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C20orf144 Gene

Domains & Families for C20orf144 Gene

Gene Families for C20orf144 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for C20orf144 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for C20orf144 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C20orf144: view

No data available for UniProtKB/Swiss-Prot for C20orf144 Gene

Function for C20orf144 Gene

genes like me logo Genes that share phenotypes with C20orf144: view

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C20orf144 Gene

Localization for C20orf144 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C20orf144 gene
Compartment Confidence
nucleus 3
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for C20orf144 Gene

Pathways & Interactions for C20orf144 Gene

SuperPathways for C20orf144 Gene

No Data Available

Interacting Proteins for C20orf144 Gene

Gene Ontology (GO) - Biological Process for C20orf144 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C20orf144 Gene

Drugs & Compounds for C20orf144 Gene

No Compound Related Data Available

Transcripts for C20orf144 Gene

mRNA/cDNA for C20orf144 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(31) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C20orf144 Gene

Chromosome 20 open reading frame 144:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for C20orf144 Gene

No ASD Table

Relevant External Links for C20orf144 Gene

GeneLoc Exon Structure for
C20orf144
ECgene alternative splicing isoforms for
C20orf144

Expression for C20orf144 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C20orf144 Gene

Protein differential expression in normal tissues from HIPED for C20orf144 Gene

This gene is overexpressed in Plasma (41.7), Testis (15.8), and Ovary (11.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C20orf144 Gene



Protein tissue co-expression partners for C20orf144 Gene

NURSA nuclear receptor signaling pathways regulating expression of C20orf144 Gene:

C20orf144

SOURCE GeneReport for Unigene cluster for C20orf144 Gene:

Hs.324104

mRNA Expression by UniProt/SwissProt for C20orf144 Gene:

Q9BQM9-CT144_HUMAN
Tissue specificity: Preferentially expressed in the testis.
genes like me logo Genes that share expression patterns with C20orf144: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C20orf144 Gene

Orthologs for C20orf144 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C20orf144 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C20H20orf144 33 34
  • 97.33 (n)
cow
(Bos Taurus)
Mammalia C20orf144 34
  • 45 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 1700003F12Rik 34
  • 43 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia C20orf144 34
  • 33 (a)
OneToOne
Species where no ortholog for C20orf144 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C20orf144 Gene

ENSEMBL:
Gene Tree for C20orf144 (if available)
TreeFam:
Gene Tree for C20orf144 (if available)

Paralogs for C20orf144 Gene

No data available for Paralogs for C20orf144 Gene

Variants for C20orf144 Gene

Sequence variations from dbSNP and Humsavar for C20orf144 Gene

SNP ID Clin Chr 20 pos Variation AA Info Type
rs1000197218 -- 33,660,914(+) C/G upstream_transcript_variant
rs1001928592 -- 33,662,021(+) G/C upstream_transcript_variant
rs1002171229 -- 33,663,460(+) C/A/G intron_variant
rs1002203850 -- 33,663,287(+) C/T intron_variant
rs1002539055 -- 33,664,261(+) G/C downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for C20orf144 Gene

Variant ID Type Subtype PubMed ID
dgv7560n54 CNV loss 21841781
nsv1065189 CNV loss 25217958
nsv585927 CNV loss 21841781
nsv833960 CNV loss 17160897
nsv833961 CNV loss 17160897
nsv954024 CNV deletion 24416366

Variation tolerance for C20orf144 Gene

Gene Damage Index Score: 6.36; 76.89% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for C20orf144 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C20orf144

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C20orf144 Gene

Disorders for C20orf144 Gene

Additional Disease Information for C20orf144

No disorders were found for C20orf144 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C20orf144 Gene

Publications for C20orf144 Gene

  1. The DNA sequence and comparative analysis of human chromosome 20. (PMID: 11780052) Deloukas P … Rogers J (Nature 2001) 2 3 4 58
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58

Products for C20orf144 Gene

Sources for C20orf144 Gene

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