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Aliases for C1orf94 Gene

Aliases for C1orf94 Gene

  • Chromosome 1 Open Reading Frame 94 2 3 5
  • Uncharacterized Protein C1orf94 3

External Ids for C1orf94 Gene

Previous GeneCards Identifiers for C1orf94 Gene

  • GC01P034303
  • GC01P034405
  • GC01P034632
  • GC01P032749

Summaries for C1orf94 Gene

GeneCards Summary for C1orf94 Gene

C1orf94 (Chromosome 1 Open Reading Frame 94) is a Protein Coding gene.

Additional gene information for C1orf94 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1orf94 Gene

Genomics for C1orf94 Gene

GeneHancer (GH) Regulatory Elements for C1orf94 Gene

Promoters and enhancers for C1orf94 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J034162 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 650.7 -1.6 -1574 5 ZSCAN4 SIN3A RAD21 ZEB1 ETS1 ZNF335 GLIS2 ZNF143 ZNF548 ZNF654 C1orf94 CSMD2 ZMYM1 ZMYM6 ENSG00000230163 LOC653160 ZSCAN20 GC01P034145
GH01J034188 Enhancer 0.5 ENCODE 11.5 +21.8 21780 0.4 SP1 NANOG POU5F1 CTBP2 C1orf94 CSMD2 PIR60480 GC01P034198 GC01M034179
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around C1orf94 on UCSC Golden Path with GeneCards custom track

Genomic Locations for C1orf94 Gene

Genomic Locations for C1orf94 Gene
52,249 bases
Plus strand

Genomic View for C1orf94 Gene

Genes around C1orf94 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C1orf94 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C1orf94 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C1orf94 Gene

Proteins for C1orf94 Gene

  • Protein details for C1orf94 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C1orf94
    Protein Accession:
    Secondary Accessions:
    • B3KVT1
    • D3DPR3
    • E9PJ76
    • Q96IC8

    Protein attributes for C1orf94 Gene

    598 amino acids
    Molecular mass:
    65353 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C1orf94 Gene


neXtProt entry for C1orf94 Gene

Post-translational modifications for C1orf94 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C1orf94 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C1orf94 Gene

Domains & Families for C1orf94 Gene

Gene Families for C1orf94 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for C1orf94 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C1orf94: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C1orf94 Gene

Function for C1orf94 Gene

Phenotypes From GWAS Catalog for C1orf94 Gene

Gene Ontology (GO) - Molecular Function for C1orf94 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 16189514
genes like me logo Genes that share ontologies with C1orf94: view
genes like me logo Genes that share phenotypes with C1orf94: view

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C1orf94 Gene

Localization for C1orf94 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C1orf94 gene
Compartment Confidence
mitochondrion 1
nucleus 1
endoplasmic reticulum 1
cytosol 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (2)
  • Nucleoplasm (2)
See all subcellular structures

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C1orf94 Gene

Pathways & Interactions for C1orf94 Gene

SuperPathways for C1orf94 Gene

No Data Available

Gene Ontology (GO) - Biological Process for C1orf94 Gene


No data available for Pathways by source and SIGNOR curated interactions for C1orf94 Gene

Drugs & Compounds for C1orf94 Gene

No Compound Related Data Available

Transcripts for C1orf94 Gene

mRNA/cDNA for C1orf94 Gene

(21) Selected AceView cDNA sequences:
(3) Additional mRNA sequences :
(2) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C1orf94 Gene

Chromosome 1 open reading frame 94:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for C1orf94 Gene

No ASD Table

Relevant External Links for C1orf94 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C1orf94 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C1orf94 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C1orf94 Gene

This gene is overexpressed in Testis (x39.4).

Protein differential expression in normal tissues from HIPED for C1orf94 Gene

This gene is overexpressed in Plasma (37.1), Platelet (21.4), and Heart (10.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C1orf94 Gene

Protein tissue co-expression partners for C1orf94 Gene

NURSA nuclear receptor signaling pathways regulating expression of C1orf94 Gene:


SOURCE GeneReport for Unigene cluster for C1orf94 Gene:

genes like me logo Genes that share expression patterns with C1orf94: view

No data available for mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C1orf94 Gene

Orthologs for C1orf94 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C1orf94 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C1orf94 34
  • 98 (a)
C1H1orf94 33
  • 97.28 (n)
(Bos Taurus)
Mammalia C3H1orf94 33
  • 83.33 (n)
C1orf94 34
  • 76 (a)
(Mus musculus)
Mammalia CK137956 16 34 33
  • 80.33 (n)
(Rattus norvegicus)
Mammalia LOC682102 33
  • 80.12 (n)
(Canis familiaris)
Mammalia C15H1orf94 33
  • 79.59 (n)
C1orf94 34
  • 64 (a)
(Monodelphis domestica)
Mammalia C1orf94 34
  • 63 (a)
(Ornithorhynchus anatinus)
Mammalia C1orf94 34
  • 45 (a)
(Gallus gallus)
Aves C1ORF94 33
  • 58.62 (n)
C1orf94 34
  • 47 (a)
(Anolis carolinensis)
Reptilia C1orf94 34
  • 39 (a)
Species where no ortholog for C1orf94 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C1orf94 Gene

Gene Tree for C1orf94 (if available)
Gene Tree for C1orf94 (if available)

Paralogs for C1orf94 Gene

No data available for Paralogs for C1orf94 Gene

Variants for C1orf94 Gene

Sequence variations from dbSNP and Humsavar for C1orf94 Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1000001633 -- 34,166,675(+) TTT/TT upstream_transcript_variant
rs1000011947 -- 34,198,889(+) G/A intron_variant
rs1000087783 -- 34,193,268(+) T/C intron_variant
rs1000088026 -- 34,182,254(+) A/G intron_variant
rs1000137817 -- 34,173,081(+) C/T genic_upstream_transcript_variant, intron_variant

Structural Variations from Database of Genomic Variants (DGV) for C1orf94 Gene

Variant ID Type Subtype PubMed ID
esv3446717 CNV insertion 20981092
esv3577807 CNV loss 25503493
nsv1076370 CNV deletion 25765185
nsv470709 CNV gain 18288195
nsv475181 CNV novel sequence insertion 20440878
nsv545964 CNV gain 21841781
nsv545966 CNV loss 21841781
nsv834646 CNV gain 17160897
nsv834657 CNV gain 17160897
nsv834669 CNV gain 17160897

Variation tolerance for C1orf94 Gene

Residual Variation Intolerance Score: 70.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.08; 80.41% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for C1orf94 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C1orf94 Gene

Disorders for C1orf94 Gene

Additional Disease Information for C1orf94

No disorders were found for C1orf94 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C1orf94 Gene

Publications for C1orf94 Gene

  1. Open reading frames associated with cancer in the dark matter of the human genome. (PMID: 25048349) Delgado AP … Narayanan R (Cancer genomics & proteomics 2014) 2 3 58
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  3. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  4. Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing. (PMID: 26871637) Yang X … Vidal M (Cell 2016) 3 58
  5. An inter-species protein-protein interaction network across vast evolutionary distance. (PMID: 27107014) Zhong Q … Vidal M (Molecular systems biology 2016) 3 58

Products for C1orf94 Gene

Sources for C1orf94 Gene

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