Aliases for C1orf56 Gene
External Ids for C1orf56 Gene
Previous GeneCards Identifiers for C1orf56 Gene
This gene is a proto-oncogene whose promoter is methylated by DNA methyltransferase 3B (DNMT3B), which represses the proto-oncogene. However, a catalytically inactive isoform of DNMT3B is overexpressed in lymphomas, leading to hypomethylation of the proto-oncogene's promoter and derepression of the proto-oncogene. [provided by RefSeq, Sep 2016]
GeneCards Summary for C1orf56 Gene
UniProtKB/Swiss-Prot Summary for C1orf56 Gene
Involved in control of cellular proliferation. Onconcogenic modifier contributing to the tumor suppressor function of DNMT3B.