Aliases for C1orf220 Gene

Subcategory (RNA class) for C1orf220 Gene

lncRNA

Quality Score for this RNA gene is

14

Aliases for C1orf220 Gene

  • Chromosome 1 Open Reading Frame 220 (Putative) 2 3 5
  • Putative Uncharacterized Protein C1orf220 4
  • Chromosome 1 Open Reading Frame 220 2
  • HSALNG0008703 169
  • Lnc-TEX35-1 170

External Ids for C1orf220 Gene

Previous GeneCards Identifiers for C1orf220 Gene

  • GC01P176780
  • GC01P178511
  • GC01P149739

Summaries for C1orf220 Gene

GeneCards Summary for C1orf220 Gene

C1orf220 (Chromosome 1 Open Reading Frame 220 (Putative)) is an RNA Gene, and is affiliated with the lncRNA class.

Additional gene information for C1orf220 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for C1orf220 Gene

Genomics for C1orf220 Gene

GeneHancer (GH) Regulatory Elements for C1orf220 Gene

Promoters and enhancers for C1orf220 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J178540 Promoter/Enhancer 2.2 FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 756.4 +0.2 246 5.6 CTCF MLX RBPJ POLR2A NR2F6 MIXL1 ETV6 L3MBTL2 RAD21 ZNF121 C1orf220 TEX35 PTPN2P1 RALGPS2 lnc-CLEC20A-8
GH01J178598 Enhancer 1.3 FANTOM5 Ensembl ENCODE dbSUPER 15.7 +63.5 63549 17.4 SP1 LCORL MYC HLF MAX NFIB CEBPG MLLT1 IKZF1 POLR2A RALGPS2 C1orf220 TEX35 TOR3A lnc-TEX35-4 lnc-TEX35-5
GH01J178580 Enhancer 1.1 FANTOM5 Ensembl ENCODE dbSUPER 17.6 +40.5 40548 5.8 SP1 LCORL NFIB POLR2A RELA IKZF2 EED RUNX3 IKZF1 NFIC C1orf220 TEX35 RALGPS2 HSALNG0008705 LOC105371632
GH01J178574 Enhancer 1 Ensembl ENCODE dbSUPER 18.1 +32.2 32249 5.2 ZNF652 SP1 ZNF384 IKZF1 PKNOX1 RXRA IKZF2 ZSCAN4 EED RFX1 lnc-CLEC20A-7 C1orf220 TEX35 ENSG00000201791 LOC105371632 lnc-TEX35-2
GH01J179016 Promoter/Enhancer 1.5 EPDnew ENCODE dbSUPER 10.6 +475.1 475081 3.2 SMARCE1 POLR2A NR2F6 L3MBTL2 RAD21 MNT TEAD4 NFIB GTF2F1 ZFX FAM20B lnc-ABL2-3 TOR3A RASAL2-AS1 C1orf220 piR-43106-014
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around C1orf220 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the C1orf220 gene promoter:
  • AML1a
  • C/EBPalpha
  • E47
  • Lhx3a
  • LHX3b
  • NF-E2
  • NF-E2 p45
  • PPAR-gamma1
  • PPAR-gamma2
  • RelA

Genomic Locations for C1orf220 Gene

Genomic Locations for C1orf220 Gene
chr1:178,542,752-178,548,889
(GRCh38/hg38)
Size:
6,138 bases
Orientation:
Plus strand
chr1:178,511,887-178,518,024
(GRCh37/hg19)
Size:
6,138 bases
Orientation:
Plus strand

Genomic View for C1orf220 Gene

Genes around C1orf220 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C1orf220 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C1orf220 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C1orf220 Gene

Proteins for C1orf220 Gene

  • Protein details for C1orf220 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5T0J3-CA220_HUMAN
    Recommended name:
    Putative uncharacterized protein C1orf220
    Protein Accession:
    Q5T0J3
    Secondary Accessions:
    • B2RN72
    • Q8NAD3

    Protein attributes for C1orf220 Gene

    Size:
    134 amino acids
    Molecular mass:
    15074 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C1orf220 Gene

Post-translational modifications for C1orf220 Gene

No Post-translational modifications

No data available for DME Specific Peptides for C1orf220 Gene

Domains & Families for C1orf220 Gene

Protein Domains for C1orf220 Gene

InterPro:
ProtoNet:
genes like me logo Genes that share domains with C1orf220: view

No data available for Gene Families , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for C1orf220 Gene

Function for C1orf220 Gene

Phenotypes From GWAS Catalog for C1orf220 Gene

genes like me logo Genes that share phenotypes with C1orf220: view

Animal Model Products

CRISPR Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C1orf220 Gene

Localization for C1orf220 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for C1orf220 Gene

Pathways & Interactions for C1orf220 Gene

PathCards logo

SuperPathways for C1orf220 Gene

No Data Available

Interacting Proteins for C1orf220 Gene

Selected Interacting proteins: Q5T0J3-CA220_HUMAN for C1orf220 Gene via IID

Gene Ontology (GO) - Biological Process for C1orf220 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C1orf220 Gene

Drugs & Compounds for C1orf220 Gene

No Compound Related Data Available

Transcripts for C1orf220 Gene

mRNA/cDNA for C1orf220 Gene

(2) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(34) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(2) RNACentral transcripts :
(2) LncBook transcripts :
(2) LNCipedia transcripts :

CRISPR Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for C1orf220 Gene

No ASD Table

Relevant External Links for C1orf220 Gene

GeneLoc Exon Structure for
C1orf220
ECgene alternative splicing isoforms for
C1orf220

Expression for C1orf220 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C1orf220 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C1orf220 Gene



NURSA nuclear receptor signaling pathways regulating expression of C1orf220 Gene:

C1orf220

SOURCE GeneReport for Unigene cluster for C1orf220 Gene:

Hs.668085
genes like me logo Genes that share expression patterns with C1orf220: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C1orf220 Gene

Orthologs for C1orf220 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for C1orf220 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C1orf220 33
  • 98 (a)
OneToOne
Species where no ortholog for C1orf220 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C1orf220 Gene

ENSEMBL:
Gene Tree for C1orf220 (if available)
TreeFam:
Gene Tree for C1orf220 (if available)

Paralogs for C1orf220 Gene

No data available for Paralogs for C1orf220 Gene

Variants for C1orf220 Gene

Sequence variations from dbSNP and Humsavar for C1orf220 Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1001530267 -- 178,544,413(+) G/A/C/T intron_variant
rs1001995434 -- 178,548,976(+) A/G downstream_transcript_variant
rs1002127270 -- 178,545,017(+) A/T intron_variant
rs1002729592 -- 178,546,695(+) T/G intron_variant
rs1003224217 -- 178,541,882(+) T/C upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for C1orf220 Gene

Variant ID Type Subtype PubMed ID
nsv527862 CNV loss 19592680

Additional Variant Information for C1orf220 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C1orf220

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for C1orf220 Gene

Disorders for C1orf220 Gene

Additional Disease Information for C1orf220

No disorders were found for C1orf220 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C1orf220 Gene

Publications for C1orf220 Gene

  1. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin EL … Gygi SP (Cell 2015) 2 3 56
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 56
  3. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 56
  4. Discovery and refinement of loci associated with lipid levels. (PMID: 24097068) Willer CJ … Global Lipids Genetics Consortium (Nature genetics 2013) 3 56
  5. Genome-wide association of echocardiographic dimensions, brachial artery endothelial function and treadmill exercise responses in the Framingham Heart Study. (PMID: 17903301) Vasan RS … Benjamin EJ (BMC medical genetics 2007) 43 56

Products for C1orf220 Gene

Sources for C1orf220 Gene