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Aliases for C1orf195 Gene

Aliases for C1orf195 Gene

  • Chromosome 1 Open Reading Frame 195 2 3 5
  • Putative Uncharacterized Protein C1orf195 3

External Ids for C1orf195 Gene

Previous GeneCards Identifiers for C1orf195 Gene

  • GC01U901261
  • GC01M015368
  • GC01M015490

Summaries for C1orf195 Gene

GeneCards Summary for C1orf195 Gene

C1orf195 (Chromosome 1 Open Reading Frame 195) is a Protein Coding gene.

Additional gene information for C1orf195 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1orf195 Gene

Genomics for C1orf195 Gene

GeneHancer (GH) Regulatory Elements for C1orf195 Gene

Promoters and enhancers for C1orf195 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J015171 Enhancer 1.3 Ensembl ENCODE dbSUPER 650.7 -1.8 -1750 3.7 MLX ZFP64 ARID4B ZNF2 ZNF121 ZNF143 FOS KLF13 SP5 MXD4 C1orf195 TMEM51 TMEM51-AS1 LOC100420251
GH01J015150 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE dbSUPER 0.4 +16.2 16222 9.3 FOXA2 MLX ZFP64 ARID4B SIN3A DMAP1 ZNF2 ZNF207 ZNF143 FOS TMEM51 TMEM51-AS1 ENSG00000237938 SPEN C1orf195
GH01J015167 Enhancer 0.9 Ensembl ENCODE dbSUPER 0.7 +2.9 2907 3.3 SP1 HLF IKZF1 FOSL2 FOS SPI1 RELA TMEM51 TMEM51-AS1 C1orf195
GH01J015184 Enhancer 1.5 FANTOM5 Ensembl ENCODE dbSUPER 0.4 -17.2 -17190 9.2 PKNOX1 FOXA2 ARID4B ZNF48 ZNF143 RXRA MIER2 REST PPARG KAT8 SPEN TMEM51-AS1 TMEM51 LOC100420251 C1orf195
GH01J015175 Enhancer 1.4 Ensembl ENCODE dbSUPER 0.4 -7.0 -7026 6.3 PKNOX1 ATF1 FOXA2 SIN3A TCF12 FOS SP5 ZNF623 SMARCA4 GLIS1 TMEM51 TMEM51-AS1 C1orf195 LOC100420251
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around C1orf195 on UCSC Golden Path with GeneCards custom track

Genomic Locations for C1orf195 Gene

Genomic Locations for C1orf195 Gene
chr1:15,164,196-15,171,624
(GRCh38/hg38)
Size:
7,429 bases
Orientation:
Minus strand
chr1:15,490,840-15,497,813
(GRCh37/hg19)
Size:
6,974 bases
Orientation:
Minus strand

Genomic View for C1orf195 Gene

Genes around C1orf195 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C1orf195 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C1orf195 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C1orf195 Gene

Proteins for C1orf195 Gene

  • Protein details for C1orf195 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5TG92-CA195_HUMAN
    Recommended name:
    Putative uncharacterized protein C1orf195
    Protein Accession:
    Q5TG92

    Protein attributes for C1orf195 Gene

    Size:
    126 amino acids
    Molecular mass:
    13826 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C1orf195 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C1orf195 Gene

Post-translational modifications for C1orf195 Gene

No Post-translational modifications

Other Protein References for C1orf195 Gene

No data available for DME Specific Peptides for C1orf195 Gene

Domains & Families for C1orf195 Gene

Protein Domains for C1orf195 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C1orf195: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C1orf195 Gene

Function for C1orf195 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C1orf195 Gene

Localization for C1orf195 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C1orf195 gene
Compartment Confidence
mitochondrion 2
nucleus 2
extracellular 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for C1orf195 Gene

Pathways & Interactions for C1orf195 Gene

SuperPathways for C1orf195 Gene

No Data Available

Interacting Proteins for C1orf195 Gene

Gene Ontology (GO) - Biological Process for C1orf195 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C1orf195 Gene

Drugs & Compounds for C1orf195 Gene

No Compound Related Data Available

Transcripts for C1orf195 Gene

mRNA/cDNA for C1orf195 Gene

(3) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :
(2) RNA Central transcripts :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for C1orf195 Gene

No ASD Table

Relevant External Links for C1orf195 Gene

GeneLoc Exon Structure for
C1orf195
ECgene alternative splicing isoforms for
C1orf195

Expression for C1orf195 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C1orf195 Gene

mRNA differential expression in normal tissues according to GTEx for C1orf195 Gene

This gene is overexpressed in Testis (x11.9), Pancreas (x5.7), and Brain - Cerebellum (x4.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C1orf195 Gene



NURSA nuclear receptor signaling pathways regulating expression of C1orf195 Gene:

C1orf195
genes like me logo Genes that share expression patterns with C1orf195: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C1orf195 Gene

Orthologs for C1orf195 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for C1orf195 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C1orf195 34
  • 97 (a)
OneToOne
Species where no ortholog for C1orf195 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C1orf195 Gene

ENSEMBL:
Gene Tree for C1orf195 (if available)
TreeFam:
Gene Tree for C1orf195 (if available)

Paralogs for C1orf195 Gene

No data available for Paralogs for C1orf195 Gene

Variants for C1orf195 Gene

Sequence variations from dbSNP and Humsavar for C1orf195 Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1000008473 -- 15,167,394(-) A/G genic_downstream_transcript_variant, intron_variant
rs1000606673 -- 15,168,762(-) A/G coding_sequence_variant, intron_variant, synonymous_variant
rs1000751101 -- 15,166,518(-) GAGA/GA genic_downstream_transcript_variant, intron_variant
rs1000887125 -- 15,166,271(-) G/A genic_downstream_transcript_variant, intron_variant
rs1001038957 -- 15,173,236(-) T/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for C1orf195 Gene

Variant ID Type Subtype PubMed ID
esv2664046 CNV deletion 23128226
esv3585302 CNV loss 21293372
nsv508913 CNV insertion 20534489
nsv833425 CNV gain 17160897

Variation tolerance for C1orf195 Gene

Gene Damage Index Score: 3.97; 59.88% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for C1orf195 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C1orf195

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C1orf195 Gene

Disorders for C1orf195 Gene

Additional Disease Information for C1orf195

No disorders were found for C1orf195 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C1orf195 Gene

Publications for C1orf195 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 3 4 58
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58

Products for C1orf195 Gene

Sources for C1orf195 Gene

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