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Aliases for C1orf162 Gene
Aliases for C1orf162 Gene
External Ids for C1orf162 Gene
- HGNC: 28344
- Entrez Gene: 128346
- Ensembl: ENSG00000143110
- UniProtKB: Q8NEQ5
Previous GeneCards Identifiers for C1orf162 Gene
- GC01P111729
- GC01P111818
- GC01P112016
- GC01P109888
Summaries for C1orf162 Gene
GeneCards Summary for C1orf162 Gene
C1orf162 (Chromosome 1 Open Reading Frame 162) is a Protein Coding gene.
Additional gene information for C1orf162 Gene
- HGNC(28344)
- Entrez Gene(128346)
- Ensembl(ENSG00000143110)
- UniProtKB(Q8NEQ5)
- Open Targets Platform(ENSG00000143110)
- Search for C1orf162 at DataMed
- Search for C1orf162 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for C1orf162 Gene
Genomics for C1orf162 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for C1orf162 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around C1orf162 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for C1orf162
- Top Transcription factor binding sites by QIAGEN in the C1orf162 gene promoter:
-
- AML1a
- c-Myc
- Evi-1
- FOXI1
- HFH-3
- Ik-3
- ISGF-3
- Max1
- TBP
- Zic3
Genomic Locations for C1orf162 Gene
Genomic Locations for C1orf162 Gene
- chr1:111,462,027-111,478,512
- (GRCh38/hg38)
- Size:
- 16,486 bases
- Orientation:
- Plus strand
- chr1:112,016,414-112,021,134
- (GRCh37/hg19)
- Size:
- 4,721 bases
- Orientation:
- Plus strand
Genomic View for C1orf162 Gene
Genes around C1orf162 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1p13.2 by HGNC
- 1p13.2 by Entrez Gene
- 1p13.2 by Ensembl
C1orf162 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for C1orf162 Gene
Proteins for C1orf162 Gene
-
Protein details for C1orf162 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8NEQ5-CA162_HUMAN
- Recommended name:
- Transmembrane protein C1orf162
- Protein Accession:
- Q8NEQ5
- Q5QNZ1
Protein attributes for C1orf162 Gene
- Size:
- 155 amino acids
- Molecular mass:
- 16886 Da
- Quaternary structure:
- No Data Available
Protein Expression for C1orf162 Gene
Post-translational modifications for C1orf162 Gene
Other Protein References for C1orf162 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Creative Diagnostics Anti-C1ORF162 (aa 4-37) polyclonal antibody
- Novus Biologicals Antibodies for C1orf162
- Invitrogen Antibodies for C1orf162 (AFLGC-C1orf162)
- antibodies-online: Show 17 available C1orf162 Antibodies ranked by validation data
Protein Products
-
OriGene Purified Proteins for C1orf162
- Search Origene for MassSpec and Protein Over-expression Lysates for C1orf162
- Origene Custom Protein Services for C1orf162
No data available for DME Specific Peptides for C1orf162 Gene
Domains & Families for C1orf162 Gene
Gene Families for C1orf162 Gene
- Human Protein Atlas (HPA):
-
- Predicted membrane proteins
Suggested Antigen Peptide Sequences for C1orf162 Gene
- GenScript: Design optimal peptide antigens:
-
- Transmembrane protein C1orf162 (CA162_HUMAN)
No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for C1orf162 Gene
Function for C1orf162 Gene
Phenotypes From GWAS Catalog for C1orf162 Gene
Phenotypes for C1orf162 Gene
- GenomeRNAi human phenotypes for C1orf162:
-
- Increased vaccinia virus (VACV) infection
- no effect
- Decreased vaccinia virus (VACV) infection
- Decreased viability ratio
- Negative genetic interaction between BLM-/- and BLM+/+
- Decreased viability
- Increased ionizing radiation sensitivity
- Increased epidermal growth factor (EGF) endocytosis, decreased transferrin (TF) endocytosis
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for C1orf162 - Select products 50% OFF >
- * C1orf162 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for C1orf162
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for C1orf162
-
Santa Cruz Biotechnology (SCBT) CRISPR for C1orf162
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for C1orf162
- Browse OriGene Inhibitory RNA Products For C1orf162
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C1orf162
Clone Products
- Applied Biological Materials (abm): Clones for C1orf162 - Select products 50% OFF >
- * C1orf162 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for C1orf162
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for C1orf162
Cell Line Products
-
Horizon Cell Lines for C1orf162
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C1orf162 Gene
Localization for C1orf162 Gene
Subcellular locations from UniProtKB/Swiss-Prot for C1orf162 Gene
- Membrane. Single-pass membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 2 |
| extracellular | 1 |
| cytosol | 1 |
| mitochondrion | 0 |
| nucleus | 0 |
| endoplasmic reticulum | 0 |
| golgi apparatus | 0 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for C1orf162 Gene
Pathways & Interactions for C1orf162 Gene
Interacting Proteins for C1orf162 Gene
GPS-Prot Interaction Network for C1orf162
No data available for Pathways by source and SIGNOR curated interactions for C1orf162 Gene
Transcripts for C1orf162 Gene
mRNA/cDNA for C1orf162 Gene
- 3 REFSEQ mRNAs :
- 6 NCBI additional mRNA sequence :
- 3 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000343534 1107 nts (view in UCSC)
- ENST00000369718 915 nts (view in UCSC)
- ENST00000464591 2308 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for C1orf162 - Select products 50% OFF >
- * C1orf162 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for C1orf162
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for C1orf162
-
Santa Cruz Biotechnology (SCBT) CRISPR for C1orf162
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for C1orf162
- Browse OriGene Inhibitory RNA Products For C1orf162
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C1orf162
Clone Products
- Applied Biological Materials (abm): Clones for C1orf162 - Select products 50% OFF >
- * C1orf162 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for C1orf162
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for C1orf162
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | ||||||||||||||||||||
| SP2: | - | - | |||||||||||||||||||||
| SP3: | - | - | - |
Relevant External Links for C1orf162 Gene
- GeneLoc Exon Structure for
- C1orf162
Expression for C1orf162 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
mRNA differential expression in normal tissues according to GTEx for C1orf162 Gene
This gene is overexpressed in Whole Blood (x26.8).
This gene is overexpressed in NK cells (30.6), Platelet (19.8), and Blymphocyte (18.6).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C1orf162 Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for C1orf162
SOURCE GeneReport for Unigene cluster for C1orf162 Gene:
Hs.288010Evidence on tissue expression from TISSUES for C1orf162 Gene
- Lung(4.3)
Primer Products
-
OriGene qPCR primer pairs for C1orf162
-
OriGene qPCR primer pairs and template standards for C1orf162
Gene Expression Assay Products
No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for C1orf162 Gene
Orthologs for C1orf162 Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | C1H1orf162 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | C3H1orf162 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | I830077J02Rik 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | LOC100363228 30 |
|
||
| Dog (Canis familiaris) |
Mammalia | C17H1orf162 30 |
|
||
| C1ORF162 31 |
|
OneToOne |
- Species where no ortholog for C1orf162 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Oppossum (Monodelphis domestica)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
- Zebrafish (Danio rerio)
Paralogs for C1orf162 Gene
No data available for Paralogs for C1orf162 Gene
Variants for C1orf162 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for C1orf162 Gene
| SNP ID | Clinical significance and condition | Chr 01 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs6703267 | - | p.Gly3Ser |
Residual Variation Intolerance Score:
75.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
6.56;
77.90% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for C1orf162 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- C1orf162
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C1orf162 Gene
Disorders for C1orf162 Gene
Additional Disease Information for C1orf162
- Genetic Association Database
- (GAD)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No disorders were found for C1orf162 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C1orf162 Gene
Publications for C1orf162 Gene
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3
- Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3
- The SARS-coronavirus-host interactome: identification of cyclophilins as target for pan-coronavirus inhibitors. (PMID: 22046132) Pfefferle S … von Brunn A (PLoS pathogens 2011) 3
- A genome-wide association study identifies a novel major locus for glycemic control in type 1 diabetes, as measured by both A1C and glucose. (PMID: 19875614) Paterson AD … Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Research Group (Diabetes 2010) 41
- The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 4
ExternalLinks
Products for C1orf162 Gene
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for C1orf162
- Search Origene for MassSpec and Protein Over-expression Lysates for C1orf162
- Origene Custom Protein Services for C1orf162
- Origene shrna, sirna, and RNAi products in human, mouse, rat for C1orf162
- Browse OriGene Inhibitory RNA Products For C1orf162
- OriGene qPCR primer pairs for C1orf162
- OriGene qPCR primer pairs and template standards for C1orf162
- OriGene CRISPR knockouts for C1orf162
- OriGene ORF clones in human for C1orf162
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For C1orf162
- Sino Biological Human cDNA Clone for C1orf162
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for C1orf162
- Novus Biologicals proteins and lysates for C1orf162
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Invitrogen Antibodies for C1orf162 (AFLGC-C1orf162)
- VectorBuilder Custom and pre-made DNA vectors for C1orf162 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for C1orf162 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for C1orf162 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for C1orf162 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for C1orf162
- antibodies-online: Show 17 available C1orf162 Antibodies ranked by validation data
- antibodies-online: Search results for available C1orf162 related products ranked by validation data
- antibodies-online: Search results for available C1orf162 related products ranked by validation data
- Horizon Cell Lines for C1orf162
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for C1orf162
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for C1orf162
- Search GeneCopoeia for miRNA 3'UTR Target clone products for C1orf162
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C1orf162
Sources for C1orf162 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB