Aliases for C1orf158 Gene
External Ids for C1orf158 Gene
- HGNC: 28567
- Entrez Gene: 93190
- Ensembl: ENSG00000157330
- UniProtKB: Q8N1D5
Previous GeneCards Identifiers for C1orf158 Gene
- GC01P012741
- GC01P011959
Summaries for C1orf158 Gene
GeneCards Summary for C1orf158 Gene
C1orf158 (Chromosome 1 Open Reading Frame 158) is a Protein Coding gene.
Additional gene information for C1orf158 Gene
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1orf158 Gene
Genomics for C1orf158 Gene
GeneHancer (GH) Regulatory Elements for C1orf158 Gene
Promoters and enhancers for C1orf158 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH01I012746 | Promoter | 0.9 | EPDnew | 550.8 | 0.0 | -5 | 0.1 | HDAC1 RFX1 MAFG ZEB2 BMI1 EP300 ZNF217 ADNP RUNX3 NR2C2 | C1orf158 AADACL3 | |
| GH01I012721 | Enhancer | 0.2 | FANTOM5 | 0.3 | -24.5 | -24513 | 0.2 | AADACL4 AADACL3 C1orf158 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around C1orf158 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for C1orf158 Gene
Genomic Locations for C1orf158 Gene
- chr1:12,746,186-12,763,699
- (GRCh38/hg38)
- Size:
- 17,514 bases
- Orientation:
- Plus strand
- chr1:12,806,163-12,823,847
- (GRCh37/hg19)
Genomic View for C1orf158 Gene
Genes around C1orf158 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1p36.21 by Ensembl
- 1p36.21 by Entrez Gene
- 1p36.21 by HGNC
C1orf158 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for C1orf158 Gene
Proteins for C1orf158 Gene
-
Protein details for C1orf158 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8N1D5-CA158_HUMAN
- Recommended name:
- Uncharacterized protein C1orf158
- Protein Accession:
- Q8N1D5
- Q5VUY4
Protein attributes for C1orf158 Gene
- Size:
- 194 amino acids
- Molecular mass:
- 23067 Da
- Quaternary structure:
- No Data Available
Protein Expression for C1orf158 Gene
Post-translational modifications for C1orf158 Gene
Other Protein References for C1orf158 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for C1orf158
- Invitrogen Antibodies for C1orf158
- Search GeneTex for Antibodies for C1orf158
Protein Products
-
OriGene Purified Proteins for C1orf158
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- Search GeneTex for Proteins for C1orf158
Assay Products
No data available for DME Specific Peptides for C1orf158 Gene
Domains & Families for C1orf158 Gene
Gene Families for C1orf158 Gene
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for C1orf158 Gene
- ProtoNet:
Graphical View of Domain Structure for InterPro Entry
No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C1orf158 Gene
Function for C1orf158 Gene
Phenotypes for C1orf158 Gene
- GenomeRNAi human phenotypes for C1orf158:
Animal Model Products
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-
-
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-
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- Search ViGene Biosciences for C1orf158
CRISPR Products
-
OriGene CRISPR knockouts for C1orf158
- genomics-online: gRNA clones - Search results for 35 available C1ORF158 gene related products
- Overview of 35 available C1ORF158 gene related products
- Applied Biological Materials CRISPR for C1orf158
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for C1orf158
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miRNA for C1orf158 Gene
- miRTarBase miRNAs that target C1orf158
-
- hsa-mir-498 (MIRT685394)
- hsa-mir-6848-3p (MIRT685395)
- hsa-mir-6843-3p (MIRT685396)
- hsa-mir-6783-3p (MIRT685397)
- hsa-mir-1343-3p (MIRT685398)
- hsa-mir-4420 (MIRT685399)
- hsa-mir-181b-3p (MIRT685400)
- hsa-mir-181b-2-3p (MIRT685401)
- hsa-mir-23b-5p (MIRT685402)
- hsa-mir-23a-5p (MIRT685403)
- hsa-mir-6829-3p (MIRT685404)
- hsa-mir-6791-3p (MIRT685405)
- hsa-mir-1304-3p (MIRT685406)
- hsa-mir-1281 (MIRT685407)
- hsa-mir-6742-3p (MIRT685408)
- hsa-mir-6852-5p (MIRT685409)
- hsa-mir-939-3p (MIRT685410)
- hsa-mir-660-3p (MIRT685411)
- hsa-mir-4485-5p (MIRT685412)
miRNA Products
- Search ViGene Biosciences for C1orf158
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for C1orf158
- Browse OriGene Inhibitory RNA Products For C1orf158
- genomics-online: shRNA clones - Search results for 35 available C1ORF158 gene related products
- Overview of 35 available C1ORF158 gene related products
-
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Clone Products
-
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- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- VectorBuilder custom plasmid, inducible vectors for C1orf158
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C1orf158
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for C1orf158
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for C1orf158
-
ViGene Biosciences adenoviral particle packaged cDNA for C1orf158 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for C1orf158 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for C1orf158 gene
No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C1orf158 Gene
Localization for C1orf158 Gene
| Compartment | Confidence |
|---|---|
| cytosol | 3 |
| nucleus | 2 |
| mitochondrion | 1 |
- Cytosol (1)
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C1orf158 Gene
Transcripts for C1orf158 Gene
mRNA/cDNA for C1orf158 Gene
- (3) REFSEQ mRNAs :
- (4) Additional mRNA sequences :
- (36) Selected AceView cDNA sequences:
- (3) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for C1orf158 Gene
CRISPR Products
-
OriGene CRISPR knockouts for C1orf158
- genomics-online: gRNA clones - Search results for 35 available C1ORF158 gene related products
- Overview of 35 available C1ORF158 gene related products
- Applied Biological Materials CRISPR for C1orf158
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for C1orf158
- GenScript: Design CRISPR guide RNA sequences for C1orf158
miRNA Products
- Search ViGene Biosciences for C1orf158
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for C1orf158
- Browse OriGene Inhibitory RNA Products For C1orf158
- genomics-online: shRNA clones - Search results for 35 available C1ORF158 gene related products
- Overview of 35 available C1ORF158 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for C1orf158 gene
Clone Products
-
OriGene ORF clones in human for C1orf158
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- VectorBuilder custom plasmid, inducible vectors for C1orf158
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C1orf158
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for C1orf158
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for C1orf158 Gene
mRNA differential expression in normal tissues according to GTEx for C1orf158 Gene
This gene is overexpressed in Testis (x34.5) and Fallopian Tube (x4.5).
This gene is overexpressed in Plasma (69.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C1orf158 Gene
NURSA nuclear receptor signaling pathways regulating expression of C1orf158 Gene:
C1orf158SOURCE GeneReport for Unigene cluster for C1orf158 Gene:
Hs.98095Primer Products
-
OriGene qPCR primer pairs for C1orf158
- genomics-online: primer clones - Search results for 35 available C1ORF158 gene related products
- Overview of 35 available C1ORF158 gene related products
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C1orf158 Gene
Orthologs for C1orf158 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | C1H1orf158 33 |
|
||
| C1orf158 34 |
|
OneToOne | |||
| cow (Bos Taurus) |
Mammalia | C16H1orf158 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | C2H1orf158 33 |
|
||
| C1orf158 34 |
|
OneToOne | |||
| mouse (Mus musculus) |
Mammalia | 1700012P22Rik 33 16 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | LOC691162 33 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | C1orf158 34 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | C1orf158 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | C21H1orf158 33 34 |
|
||
| tropical clawed frog (Silurana tropicalis) |
Amphibia | LOC100490433 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | LOC100003307 33 |
|
||
| C11H1orf158 34 |
|
OneToOne | |||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToOne |
- Species where no ortholog for C1orf158 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for C1orf158 Gene
No data available for Paralogs for C1orf158 Gene
Variants for C1orf158 Gene
| SNP ID | Clin | Chr 01 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000832283 | -- | 12,760,537(+) | C/T | intron_variant | |
| rs1000899706 | -- | 12,746,870(+) | T/C | intron_variant | |
| rs1000954203 | -- | 12,753,192(+) | C/T | intron_variant | |
| rs1001026343 | -- | 12,752,836(+) | T/G | intron_variant | |
| rs1001090715 | -- | 12,748,624(+) | G/C | intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv19n100 | CNV | loss | 25217958 |
| esv2664000 | CNV | deletion | 23128226 |
| esv3585239 | CNV | loss | 21293372 |
| nsv1000876 | CNV | gain | 25217958 |
| nsv1011540 | CNV | loss | 25217958 |
| nsv466394 | CNV | gain | 19166990 |
| nsv470695 | CNV | loss | 18288195 |
| nsv528703 | CNV | loss | 19592680 |
| nsv545445 | CNV | gain | 21841781 |
| nsv832869 | CNV | gain+loss | 17160897 |
| nsv999658 | CNV | gain | 25217958 |
Residual Variation Intolerance Score:
84.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
3.93;
59.50% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for C1orf158 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- C1orf158
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C1orf158 Gene
Disorders for C1orf158 Gene
Additional Disease Information for C1orf158
No disorders were found for C1orf158 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C1orf158 Gene
Publications for C1orf158 Gene
- The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 3 4 58
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 58
- hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P … Vidal M (Genomics 2007) 3 58
Products for C1orf158 Gene
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- Cyagen custom Knockout/knockin (KOKI) mouse models for C1orf158
- VectorBuilder custom plasmid, inducible vectors for C1orf158
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C1orf158
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneTex for Antibodies for C1orf158
- Search GeneTex for Proteins for C1orf158
- ViGene Biosciences adenoviral particle packaged cDNA for C1orf158 gene
- ViGene Biosciences lentiviral particle packaged cDNA for C1orf158 gene
- ViGene Biosciences ready-to-package AAV shRNAs for C1orf158 gene
- Search ViGene Biosciences for C1orf158
- Horizon Cell Lines for C1orf158
- genomics-online: cdna clones - Search results for 35 available C1ORF158 gene related products
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- Overview of 35 available C1ORF158 gene related products
Sources for C1orf158 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems