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Aliases for C1orf146 Gene

Aliases for C1orf146 Gene

  • Chromosome 1 Open Reading Frame 146 2 3 5
  • Uncharacterized Protein C1orf146 3

External Ids for C1orf146 Gene

Previous GeneCards Identifiers for C1orf146 Gene

  • GC01P092397
  • GC01P092456
  • GC01P092683
  • GC01P090803

Summaries for C1orf146 Gene

GeneCards Summary for C1orf146 Gene

C1orf146 (Chromosome 1 Open Reading Frame 146) is a Protein Coding gene.

Additional gene information for C1orf146 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1orf146 Gene

Genomics for C1orf146 Gene

GeneHancer (GH) Regulatory Elements for C1orf146 Gene

Promoters and enhancers for C1orf146 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J092229 Promoter 0.5 EPDnew 650.4 +11.2 11216 0.1 ACTBP12 C1orf146
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around C1orf146 on UCSC Golden Path with GeneCards custom track

Genomic Locations for C1orf146 Gene

Genomic Locations for C1orf146 Gene
27,902 bases
Plus strand

Genomic View for C1orf146 Gene

Genes around C1orf146 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C1orf146 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C1orf146 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C1orf146 Gene

Proteins for C1orf146 Gene

  • Protein details for C1orf146 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C1orf146
    Protein Accession:
    Secondary Accessions:
    • Q5VVC4

    Protein attributes for C1orf146 Gene

    180 amino acids
    Molecular mass:
    20418 Da
    Quaternary structure:
    No Data Available
    • Sequence=CAH70760.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for C1orf146 Gene

Post-translational modifications for C1orf146 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C1orf146 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C1orf146 Gene

Domains & Families for C1orf146 Gene

Gene Families for C1orf146 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for C1orf146 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C1orf146: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C1orf146 Gene

Function for C1orf146 Gene

genes like me logo Genes that share phenotypes with C1orf146: view

Animal Model Products

miRNA for C1orf146 Gene

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C1orf146 Gene

Localization for C1orf146 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C1orf146 gene
Compartment Confidence
nucleus 2
cytosol 2
extracellular 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for C1orf146 Gene

Pathways & Interactions for C1orf146 Gene

SuperPathways for C1orf146 Gene

No Data Available

Interacting Proteins for C1orf146 Gene

Gene Ontology (GO) - Biological Process for C1orf146 Gene


No data available for Pathways by source and SIGNOR curated interactions for C1orf146 Gene

Drugs & Compounds for C1orf146 Gene

No Compound Related Data Available

Transcripts for C1orf146 Gene

mRNA/cDNA for C1orf146 Gene

(10) Selected AceView cDNA sequences:
(2) Additional mRNA sequences :
(2) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C1orf146 Gene

Chromosome 1 open reading frame 146:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for C1orf146 Gene

No ASD Table

Relevant External Links for C1orf146 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C1orf146 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C1orf146 Gene

mRNA differential expression in normal tissues according to GTEx for C1orf146 Gene

This gene is overexpressed in Testis (x22.9), Brain - Cerebellar Hemisphere (x5.2), and Brain - Cerebellum (x4.2).

NURSA nuclear receptor signaling pathways regulating expression of C1orf146 Gene:


SOURCE GeneReport for Unigene cluster for C1orf146 Gene:

genes like me logo Genes that share expression patterns with C1orf146: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C1orf146 Gene

Orthologs for C1orf146 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C1orf146 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C1orf146 34
  • 100 (a)
C1H1orf146 33
  • 100 (n)
(Bos Taurus)
Mammalia C3H1orf146 33
  • 93.33 (n)
C1orf146 34
  • 91 (a)
(Canis familiaris)
Mammalia C6H1orf146 33
  • 92.78 (n)
C1orf146 34
  • 88 (a)
(Mus musculus)
Mammalia 1700028K03Rik 16 34 33
  • 85.98 (n)
(Rattus norvegicus)
Mammalia LOC689986 33
  • 84.92 (n)
(Monodelphis domestica)
Mammalia C1orf146 34
  • 51 (a)
(Gallus gallus)
Aves C1ORF146 34 33
  • 66.87 (n)
(Anolis carolinensis)
Reptilia C1orf146 34
  • 60 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC101733338 33
  • 63.92 (n)
(Danio rerio)
Actinopterygii gb:ex154042 33
  • 50.46 (n)
C6H1orf146 34
  • 40 (a)
Species where no ortholog for C1orf146 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C1orf146 Gene

Gene Tree for C1orf146 (if available)
Gene Tree for C1orf146 (if available)

Paralogs for C1orf146 Gene Pseudogenes for C1orf146 Gene

genes like me logo Genes that share paralogs with C1orf146: view

No data available for Paralogs for C1orf146 Gene

Variants for C1orf146 Gene

Sequence variations from dbSNP and Humsavar for C1orf146 Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1000179844 -- 92,232,227(+) T/G intron_variant
rs1000300100 -- 92,243,331(+) G/C intron_variant
rs1000332056 -- 92,243,554(+) T/C intron_variant
rs1000344774 -- 92,222,130(+) A/G intron_variant
rs1000494490 -- 92,227,313(+) C/A intron_variant

Structural Variations from Database of Genomic Variants (DGV) for C1orf146 Gene

Variant ID Type Subtype PubMed ID
esv2714684 CNV deletion 23290073
nsv830592 CNV gain 17160897
nsv946075 CNV duplication 23825009

Variation tolerance for C1orf146 Gene

Residual Variation Intolerance Score: 61.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.72; 32.73% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for C1orf146 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C1orf146 Gene

Disorders for C1orf146 Gene

Additional Disease Information for C1orf146

No disorders were found for C1orf146 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C1orf146 Gene

Publications for C1orf146 Gene

  1. Finishing the euchromatic sequence of the human genome. (PMID: 15496913) International Human Genome Sequencing Consortium (Nature 2004) 2 3 58
  2. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 4 58
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 58
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58

Products for C1orf146 Gene

Sources for C1orf146 Gene

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