C19orf84 Gene (Protein Coding)

Chromosome 19 Open Reading Frame 84

GC19M051388
GIFtS:
21
See more...

Aliases for C19orf84 Gene

Aliases for C19orf84 Gene

  • Chromosome 19 Open Reading Frame 84 2 3 5
  • Uncharacterized Protein C19orf84 3 4
  • C19orf84 5

External Ids for C19orf84 Gene

Previous GeneCards Identifiers for C19orf84 Gene

  • GC19M051892

Summaries for C19orf84 Gene

GeneCards Summary for C19orf84 Gene

C19orf84 (Chromosome 19 Open Reading Frame 84) is a Protein Coding gene.

Additional gene information for C19orf84 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for C19orf84 Gene

Genomics for C19orf84 Gene

GeneHancer (GH) Regulatory Elements Pubs

Download GeneHancer 2017 data
Promoters and enhancers for C19orf84 Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH19J051388 Promoter/Enhancer 1.7 EPDnew Ensembl ENCODE CraniofacialAtlas 270.9 +0.4 369 3.2 TBP IKZF1 SMAD5 ZIC2 THAP11 GTF2E2 VEZF1 SMAD4 SAP130 TRIM25 C19orf84 HSALNG0127212 SHANK1 SYT3 IGLON5 LRRC4B LIM2 LOC105372446
GH19J051393 Promoter/Enhancer 2 FANTOM5 Ensembl ENCODE CraniofacialAtlas 20.4 -4.1 -4138 3.5 CHD2 TBP BCL11A MXD4 SP1 MNT IKZF1 SMAD5 ETS1 MBD2 ENSG00000268889 piR-61945-263 ZNF841 ZNF577 ZNF616 ZNF766 ZNF432 ZNF175 ZNF836 ZNF613
GH19J051386 Promoter/Enhancer 1.1 EPDnew ENCODE CraniofacialAtlas 15.1 +3.0 2993 1.4 IKZF1 FOXA2 SAP130 ETV4 RARA TEAD3 SOX5 NR2F1 RFX1 NR2F6 HSALNG0127211 LIM2 LOC105372446 C19orf84 NKG7
GH19J051392 Enhancer 0.3 FANTOM5 7.2 -2.3 -2316 0.2 ZNF592 ENSG00000268889 C19orf84 SIGLEC14 LOC105372446 SIGLEC10
GH19J051416 Promoter/Enhancer 1.4 EPDnew Ensembl ENCODE 0.3 -26.9 -26909 2.2 BCL11A VEZF1 IRF4 EBF1 SMARCA5 FOSL1 CBFB TAF1 SPI1 POLR2A SIGLEC10 SIGLEC10-AS1 C19orf84
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around C19orf84 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for C19orf84

Genomic Locations for C19orf84 Gene

Latest Assembly
chr19:51,388,289-51,390,591
(GRCh38/hg38)
Size:
2,303 bases
Orientation:
Minus strand

Previous Assembly
chr19:51,891,543-51,893,845
(GRCh37/hg19 by Entrez Gene)
Size:
2,303 bases
Orientation:
Minus strand

chr19:51,891,543-51,893,828
(GRCh37/hg19 by Ensembl)
Size:
2,286 bases
Orientation:
Minus strand

Genomic View for C19orf84 Gene

Genes around C19orf84 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C19orf84 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C19orf84 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for C19orf84 Gene

Proteins for C19orf84 Gene

Products:

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  2. Protein products for research
  3. Assay products for research

  • Protein details for C19orf84 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    I3L1E1-CS084_HUMAN
    Recommended name:
    Uncharacterized protein C19orf84
    Protein Accession:
    I3L1E1

    Protein attributes for C19orf84 Gene

    Size:
    186 amino acids
    Molecular mass:
    19614 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C19orf84 Gene

Protein Expression for C19orf84 Gene

See protein expression from ProteomicsDB, MOPED, PaxDb, and MaxQB

Post-translational modifications for C19orf84 Gene

No Post-translational modifications

Other Protein References for C19orf84 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C19orf84 Gene

Domains & Families for C19orf84 Gene

Gene Families for C19orf84 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for C19orf84 Gene

InterPro:
ProtoNet:
genes like me logo Genes that share domains with C19orf84: view

No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for C19orf84 Gene

Function for C19orf84 Gene

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  2. CRISPR products for research
  3. miRNA products for research
  4. Inhibitory RNAs for research
  5. Clone products for research
  6. Cell Lines for research

Phenotypes for C19orf84 Gene

GenomeRNAi human phenotypes for C19orf84:
genes like me logo Genes that share phenotypes with C19orf84: view

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C19orf84

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C19orf84 Gene

Localization for C19orf84 Gene

Subcellular locations from the

Human Protein Atlas (HPA)
  • Vesicles (2)
See all subcellular structures

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for C19orf84 Gene

Pathways & Interactions for C19orf84 Gene

PathCards logo

SuperPathways for C19orf84 Gene

No Data Available

Interacting Proteins for C19orf84 Gene

Gene Ontology (GO) - Biological Process for C19orf84 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C19orf84 Gene

Drugs & Compounds for C19orf84 Gene

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  1. Drug products for research
No Compound Related Data Available

Transcripts for C19orf84 Gene

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mRNA/cDNA for C19orf84 Gene

1 REFSEQ mRNAs :
3 NCBI additional mRNA sequence :
2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C19orf84

Alternative Splicing Database (ASD) splice patterns (SP) for C19orf84 Gene

No ASD Table

Relevant External Links for C19orf84 Gene

GeneLoc Exon Structure for
C19orf84

Expression for C19orf84 Gene

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mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for C19orf84 Gene

mRNA expression in normal human tissues for C19orf84 Gene
mRNA expression by GTEx for C19orf84 Gene

mRNA differential expression in normal tissues according to GTEx for C19orf84 Gene

This gene is overexpressed in Testis (x42.9).

Protein differential expression in normal tissues from HIPED for C19orf84 Gene

This gene is overexpressed in Placenta (42.9), Esophagus (18.7), and Lung (7.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C19orf84 Gene



Protein tissue co-expression partners for C19orf84 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for C19orf84

genes like me logo Genes that share expression patterns with C19orf84: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C19orf84 Gene

Orthologs for C19orf84 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C19orf84 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
 Mammalia LOC748798 30
  • 98.92 (n)
Cow
(Bos Taurus)
 Mammalia LOC100848300 30
  • 73.7 (n)
Mouse
(Mus musculus)
 Mammalia Lim2 31 31
  • 61 (a)
 OneToMany
Species where no ortholog for C19orf84 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for C19orf84 Gene

ENSEMBL:
Gene Tree for C19orf84 (if available)
TreeFam:
Gene Tree for C19orf84 (if available)

Paralogs for C19orf84 Gene

No data available for Paralogs for C19orf84 Gene

Variants for C19orf84 Gene

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  1. SNP Genotyping and Copy Number Assays for research

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for C19orf84 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for C19orf84 Gene

Variant ID Type Subtype PubMed ID
esv21876 CNV loss 19812545
nsv1140251 OTHER inversion 24896259

Variation tolerance for C19orf84 Gene

Gene Damage Index Score: 9.37; 88.43% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for C19orf84 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C19orf84

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for C19orf84 Gene

Disorders for C19orf84 Gene

Additional Disease Information for C19orf84

Atlas
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
Open Targets Platform

No disorders were found for C19orf84 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C19orf84 Gene

Publications for C19orf84 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3
  2. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J … Lucas SM (Nature 2004) 4

ExternalLinks

View latest publications for C19orf84 gene in Mastermind

Products for C19orf84 Gene

Sources for C19orf84 Gene