Aliases for C19orf81 Gene

Aliases for C19orf81 Gene

  • Chromosome 19 Open Reading Frame 81 2 3 5
  • Putative Uncharacterized Protein C19orf81 3 4
  • C19orf81 5

External Ids for C19orf81 Gene

Previous GeneCards Identifiers for C19orf81 Gene

  • GC19P051153
  • GC19P050632

Summaries for C19orf81 Gene

GeneCards Summary for C19orf81 Gene

C19orf81 (Chromosome 19 Open Reading Frame 81) is a Protein Coding gene.

Additional gene information for C19orf81 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for C19orf81 Gene

Genomics for C19orf81 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for C19orf81 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J050649 Promoter/Enhancer 1.3 Ensembl ENCODE 600.7 +0.4 413 0.8 ARHGAP35 TEAD4 PRDM10 RFX1 SIX5 IKZF1 ZNF692 MTA2 ZNF143 POLR2A C19orf81 POLD1 IRF3 NUP62 PRMT1 ENSG00000268047 SIGLEC17P BCL2L12 PTOV1 ENSG00000267808
GH19J050648 Enhancer 0.6 FANTOM5 600.7 -1.2 -1205 0.2 RCOR1 RELA RELB RUNX3 IKZF1 NR2F1 TBX21 ZNF217 SPI1 IKZF2 C19orf81 KLK4 KLK14 KCNC3 SYT3 ACP4
GH19J050650 Enhancer 0.4 Ensembl 600.7 -0.5 -544 0.2 CBLL2 ZNF791 CTCF ZNF416 C19orf81 PRMT1 IRF3 SYT3
GH19J050657 Promoter/Enhancer 2 EPDnew Ensembl ENCODE CraniofacialAtlas 25.8 +9.3 9259 3.4 SP1 CREB1 PRDM10 ZNF629 ZNF512 LEF1 ZNF692 TARDBP JUND DDX20 lnc-SHANK1-3 SYT3 POLD1 NUP62 PTOV1-AS2 IRF3 ZNF175 PNKP CTU1 C19orf81
GH19J051593 Promoter/Enhancer 1.6 Ensembl ENCODE CraniofacialAtlas 6.9 +944.8 944756 2.4 SP1 CREB1 ATF7 PRDM10 ZNF512 SIX5 IKZF1 LARP7 GABPA MTA2 ENSG00000269388 LINC01530 ZNF175 C19orf81 ENSG00000267808 SIGLEC14 SIGLEC12 lnc-ZNF175-1 SIGLEC5
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around C19orf81 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for C19orf81

Genomic Locations for C19orf81 Gene

Genomic Locations for C19orf81 Gene
chr19:50,649,445-50,659,310
(GRCh38/hg38)
Size:
9,866 bases
Orientation:
Plus strand
chr19:51,152,702-51,162,567
(GRCh37/hg19)
Size:
9,866 bases
Orientation:
Plus strand

Genomic View for C19orf81 Gene

Genes around C19orf81 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C19orf81 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C19orf81 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C19orf81 Gene

Proteins for C19orf81 Gene

  • Protein details for C19orf81 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    C9J6K1-CS081_HUMAN
    Recommended name:
    Putative uncharacterized protein C19orf81
    Protein Accession:
    C9J6K1

    Protein attributes for C19orf81 Gene

    Size:
    198 amino acids
    Molecular mass:
    22444 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C19orf81 Gene

Post-translational modifications for C19orf81 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C19orf81 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C19orf81 Gene

Domains & Families for C19orf81 Gene

Gene Families for C19orf81 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for C19orf81 Gene

InterPro:
ProtoNet:
genes like me logo Genes that share domains with C19orf81: view

No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for C19orf81 Gene

Function for C19orf81 Gene

Phenotypes From GWAS Catalog for C19orf81 Gene

genes like me logo Genes that share phenotypes with C19orf81: view

Animal Models for C19orf81 Gene

MGI Knock Outs for C19orf81:

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C19orf81

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for C19orf81 Gene

Localization for C19orf81 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C19orf81 gene
Compartment Confidence
extracellular 2
cytoskeleton 2
nucleus 1
cytosol 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Aggresome (2)
  • Vesicles (2)
See all subcellular structures

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C19orf81 Gene

Pathways & Interactions for C19orf81 Gene

PathCards logo

SuperPathways for C19orf81 Gene

No Data Available

Interacting Proteins for C19orf81 Gene

Gene Ontology (GO) - Biological Process for C19orf81 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C19orf81 Gene

Drugs & Compounds for C19orf81 Gene

No Compound Related Data Available

Transcripts for C19orf81 Gene

mRNA/cDNA for C19orf81 Gene

1 REFSEQ mRNAs :
1 NCBI additional mRNA sequence :
3 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C19orf81

Alternative Splicing Database (ASD) splice patterns (SP) for C19orf81 Gene

No ASD Table

Relevant External Links for C19orf81 Gene

GeneLoc Exon Structure for
C19orf81

Expression for C19orf81 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for C19orf81 Gene

mRNA differential expression in normal tissues according to GTEx for C19orf81 Gene

This gene is overexpressed in Testis (x8.2), Pituitary (x7.9), and Brain - Cerebellar Hemisphere (x4.5).

Protein differential expression in normal tissues from HIPED for C19orf81 Gene

This gene is overexpressed in Plasma (62.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C19orf81 Gene



Protein tissue co-expression partners for C19orf81 Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for C19orf81

SOURCE GeneReport for Unigene cluster for C19orf81 Gene:

Hs.531650
genes like me logo Genes that share expression patterns with C19orf81: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C19orf81 Gene

Orthologs for C19orf81 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C19orf81 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia C19orf81 31
  • 94 (a)
OneToOne
Dog
(Canis familiaris)
Mammalia C1H19orf81 30
  • 86.82 (n)
C19orf81 31
  • 77 (a)
OneToOne
Cow
(Bos Taurus)
Mammalia C18H19orf81 30
  • 85.45 (n)
C19orf81 31
  • 72 (a)
OneToOne
Mouse
(Mus musculus)
Mammalia 1700008O03Rik 30 17 31
  • 78.8 (n)
OneToOne
Platypus
(Ornithorhynchus anatinus)
Mammalia C19orf81 31
  • 51 (a)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia C19orf81 31
  • 64 (a)
OneToOne
Sea Squirt
(Ciona savignyi)
Ascidiacea -- 31
  • 14 (a)
OneToOne
Species where no ortholog for C19orf81 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for C19orf81 Gene

ENSEMBL:
Gene Tree for C19orf81 (if available)
TreeFam:
Gene Tree for C19orf81 (if available)

Paralogs for C19orf81 Gene

No data available for Paralogs for C19orf81 Gene

Variants for C19orf81 Gene

Additional dbSNP identifiers (rs#s) for C19orf81 Gene

Structural Variations from Database of Genomic Variants (DGV) for C19orf81 Gene

Variant ID Type Subtype PubMed ID
esv3574587 CNV gain 25503493
nsv1072893 CNV deletion 25765185
nsv1140251 OTHER inversion 24896259
nsv579950 CNV loss 21841781
nsv828583 CNV loss 20364138
nsv953605 CNV deletion 24416366

Variation tolerance for C19orf81 Gene

Gene Damage Index Score: 1.77; 33.51% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for C19orf81 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C19orf81

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for C19orf81 Gene

Disorders for C19orf81 Gene

No disorders were found for C19orf81 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C19orf81 Gene

Publications for C19orf81 Gene

  1. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J … Lucas SM (Nature 2004) 4

Products for C19orf81 Gene

Sources for C19orf81 Gene