Aliases for C19orf44 Gene

Aliases for C19orf44 Gene

  • Chromosome 19 Open Reading Frame 44 2 3 5
  • Uncharacterized Protein C19orf44 3 4
  • C19orf44 5
  • FLJ21742 2

External Ids for C19orf44 Gene

Previous GeneCards Identifiers for C19orf44 Gene

  • GC19P016469
  • GC19P016607
  • GC19P016175
  • GC19P016578
  • GC19P016816
  • GC19P020445
  • GC19P020583
  • GC19P020698
  • GC19P022208
  • GC19P017593
  • GC19P018261
  • GC19P018663
  • GC19P018969
  • GC19P019295
  • GC19P019623
  • GC19P019986
  • GC19P020301

Summaries for C19orf44 Gene

GeneCards Summary for C19orf44 Gene

C19orf44 (Chromosome 19 Open Reading Frame 44) is a Protein Coding gene. Diseases associated with C19orf44 include Branchiootorenal Syndrome 1 and Branchiootorenal Syndrome.

Additional gene information for C19orf44 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for C19orf44 Gene

Genomics for C19orf44 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for C19orf44 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around C19orf44 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for C19orf44

Top Transcription factor binding sites by QIAGEN in the C19orf44 gene promoter:
  • aMEF-2
  • CUTL1
  • E47
  • Hand1
  • MEF-2
  • MEF-2A
  • Pax-4a
  • POU2F1
  • POU2F1a

Genomic Locations for C19orf44 Gene

Genomic Locations for C19orf44 Gene
chr19:16,496,382-16,521,369
(GRCh38/hg38)
Size:
24,988 bases
Orientation:
Plus strand
chr19:16,607,122-16,632,163
(GRCh37/hg19)
Size:
25,042 bases
Orientation:
Plus strand

Genomic View for C19orf44 Gene

Genes around C19orf44 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C19orf44 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C19orf44 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C19orf44 Gene

Proteins for C19orf44 Gene

  • Protein details for C19orf44 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H6X5-CS044_HUMAN
    Recommended name:
    Uncharacterized protein C19orf44
    Protein Accession:
    Q9H6X5
    Secondary Accessions:
    • Q8N6Y7

    Protein attributes for C19orf44 Gene

    Size:
    657 amino acids
    Molecular mass:
    71343 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C19orf44 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C19orf44 Gene

Post-translational modifications for C19orf44 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for C19orf44 Gene

Domains & Families for C19orf44 Gene

Gene Families for C19orf44 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for C19orf44 Gene

InterPro:
ProtoNet:
genes like me logo Genes that share domains with C19orf44: view

No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for C19orf44 Gene

Function for C19orf44 Gene

Phenotypes From GWAS Catalog for C19orf44 Gene

Gene Ontology (GO) - Molecular Function for C19orf44 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with C19orf44: view
genes like me logo Genes that share phenotypes with C19orf44: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C19orf44

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C19orf44 Gene

Localization for C19orf44 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C19orf44 gene
Compartment Confidence
nucleus 3
cytosol 3

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nuclear bodies (2)
  • Nucleoplasm (2)
See all subcellular structures

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C19orf44 Gene

Pathways & Interactions for C19orf44 Gene

PathCards logo

SuperPathways for C19orf44 Gene

No Data Available

Gene Ontology (GO) - Biological Process for C19orf44 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C19orf44 Gene

Drugs & Compounds for C19orf44 Gene

No Compound Related Data Available

Transcripts for C19orf44 Gene

mRNA/cDNA for C19orf44 Gene

2 REFSEQ mRNAs :
8 NCBI additional mRNA sequence :
8 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C19orf44

Alternative Splicing Database (ASD) splice patterns (SP) for C19orf44 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b · 7c ^ 8 ^ 9a · 9b ^ 10
SP1:
SP2:
SP3: -
SP4: - -
SP5:

Relevant External Links for C19orf44 Gene

GeneLoc Exon Structure for
C19orf44

Expression for C19orf44 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for C19orf44 Gene

Protein differential expression in normal tissues from HIPED for C19orf44 Gene

This gene is overexpressed in Heart (39.1) and Lung (29.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C19orf44 Gene



Protein tissue co-expression partners for C19orf44 Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for C19orf44

SOURCE GeneReport for Unigene cluster for C19orf44 Gene:

Hs.631627

Evidence on tissue expression from TISSUES for C19orf44 Gene

  • Nervous system(2.2)
genes like me logo Genes that share expression patterns with C19orf44: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for C19orf44 Gene

Orthologs for C19orf44 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C19orf44 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia C19H19orf44 30
  • 99.31 (n)
C19orf44 31
  • 99 (a)
OneToOne
Cow
(Bos Taurus)
Mammalia C7H19orf44 30
  • 73.98 (n)
C19orf44 31
  • 59 (a)
OneToOne
Dog
(Canis familiaris)
Mammalia C20H19orf44 30
  • 73.77 (n)
C19orf44 31
  • 59 (a)
OneToOne
Rat
(Rattus norvegicus)
Mammalia RGD1311847 30
  • 66.84 (n)
Mouse
(Mus musculus)
Mammalia 1700030K09Rik 30 17 31
  • 66.56 (n)
OneToOne
Oppossum
(Monodelphis domestica)
Mammalia C19orf44 31
  • 44 (a)
OneToOne
Platypus
(Ornithorhynchus anatinus)
Mammalia C19orf44 31
  • 39 (a)
OneToOne
Chicken
(Gallus gallus)
Aves C19orf44 31
  • 29 (a)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia C19orf44 31
  • 32 (a)
OneToOne
Zebrafish
(Danio rerio)
Actinopterygii C22H19orf44 31
  • 27 (a)
OneToOne
Sea Squirt
(Ciona savignyi)
Ascidiacea -- 31
  • 33 (a)
OneToOne
Species where no ortholog for C19orf44 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for C19orf44 Gene

ENSEMBL:
Gene Tree for C19orf44 (if available)
TreeFam:
Gene Tree for C19orf44 (if available)

Paralogs for C19orf44 Gene

No data available for Paralogs for C19orf44 Gene

Variants for C19orf44 Gene

Additional dbSNP identifiers (rs#s) for C19orf44 Gene

Structural Variations from Database of Genomic Variants (DGV) for C19orf44 Gene

Variant ID Type Subtype PubMed ID
esv3370089 CNV insertion 20981092

Variation tolerance for C19orf44 Gene

Residual Variation Intolerance Score: 13.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.06; 21.62% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for C19orf44 Gene

Human Gene Mutation Database (HGMD)
C19orf44
SNPedia medical, phenotypic, and genealogical associations of SNPs for
C19orf44

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for C19orf44 Gene

Disorders for C19orf44 Gene

MalaCards: The human disease database

(2) MalaCards diseases for C19orf44 Gene - From: DISEASES

Disorder Aliases PubMed IDs
branchiootorenal syndrome 1
  • bor1
branchiootorenal syndrome
  • branchiootorenal dysplasia
- elite association - COSMIC cancer census association via MalaCards
genes like me logo Genes that share disorders with C19orf44: view

No data available for UniProtKB/Swiss-Prot and Genatlas for C19orf44 Gene

Publications for C19orf44 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3
  2. A reference map of the human binary protein interactome. (PMID: 32296183) Luck K … Calderwood MA (Nature 2020) 3
  3. VIRMA mediates preferential m6A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. (PMID: 29507755) Yue Y … Liu J (Cell discovery 2018) 3
  4. RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination. (PMID: 29117863) Choudhury NR … Michlewski G (BMC biology 2017) 3
  5. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3

Products for C19orf44 Gene

Sources for C19orf44 Gene