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Aliases for C19orf44 Gene

Aliases for C19orf44 Gene

  • Chromosome 19 Open Reading Frame 44 2 3 5

External Ids for C19orf44 Gene

Previous GeneCards Identifiers for C19orf44 Gene

  • GC19P016469
  • GC19P016607
  • GC19P016175
  • GC19P016578
  • GC19P016816
  • GC19P017593
  • GC19P018261
  • GC19P018663
  • GC19P018969
  • GC19P019295

Summaries for C19orf44 Gene

GeneCards Summary for C19orf44 Gene

C19orf44 (Chromosome 19 Open Reading Frame 44) is a Protein Coding gene.

Additional gene information for C19orf44 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C19orf44 Gene

Genomics for C19orf44 Gene

GeneHancer (GH) Regulatory Elements for C19orf44 Gene

Promoters and enhancers for C19orf44 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19I016495 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 593.2 +0.1 140 1.8 HDGF PKNOX1 SMAD1 ARNT ARID4B SIN3A DMAP1 YY1 POLR2B ZNF766 C19orf44 CALR3 CHERP ENSG00000268743 RN7SL146P GC19M016221 ENSG00000141979
GH19I017106 Enhancer 1.7 FANTOM5 Ensembl ENCODE dbSUPER 90.2 +612.9 612879 4.4 HDGF ZNF493 ZFP64 SIN3A GLI4 ZNF2 IRF4 ZNF121 GLIS2 ZNF213 CHERP ENSG00000268743 ENSG00000269578 C19orf44 ENSG00000267904 ENSG00000268087 GTPBP3 SIN3B MYO9B SMIM7
GH19I017336 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 66.5 +841.0 841045 2.5 CLOCK FEZF1 DMAP1 IRF4 YY1 ZNF213 E2F8 ZNF143 ZNF548 SP3 GTPBP3 CHERP ENSG00000269578 ENSG00000268743 IQCN COLGALT1 C19orf44 SIN3B HAUS8 MVB12A
GH19I016063 Promoter/Enhancer 2.7 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 45.1 -423.4 -423398 18.7 CLOCK FEZF1 DMAP1 IRF4 E2F8 ZNF143 ZNF263 MCM3 SP3 MEF2D TPM4 AKAP8 CHERP ENSG00000269578 C19orf44 BRD4 ENSG00000267904 ENSG00000268087 SMIM7 MED26
GH19I017307 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE 36.6 +814.4 814417 5.6 HDGF PKNOX1 FOXA2 ARID4B NEUROD1 SIN3A DMAP1 ZNF2 IRF4 YY1 ABHD8 DDA1 CHERP MRPL34 C19orf44 ENSG00000268743 SIN3B ENSG00000269427 ENSG00000269044 ENSG00000267904
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around C19orf44 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the C19orf44 gene promoter:

Genomic Locations for C19orf44 Gene

Genomic Locations for C19orf44 Gene
25,059 bases
Plus strand

Genomic View for C19orf44 Gene

Genes around C19orf44 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C19orf44 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C19orf44 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C19orf44 Gene

Proteins for C19orf44 Gene

  • Protein details for C19orf44 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C19orf44
    Protein Accession:
    Secondary Accessions:
    • Q8N6Y7

    Protein attributes for C19orf44 Gene

    657 amino acids
    Molecular mass:
    71343 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C19orf44 Gene


neXtProt entry for C19orf44 Gene

Post-translational modifications for C19orf44 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for C19orf44 Gene

Domains & Families for C19orf44 Gene

Gene Families for C19orf44 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for C19orf44 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C19orf44: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C19orf44 Gene

Function for C19orf44 Gene

Phenotypes From GWAS Catalog for C19orf44 Gene

Gene Ontology (GO) - Molecular Function for C19orf44 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with C19orf44: view
genes like me logo Genes that share phenotypes with C19orf44: view

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C19orf44 Gene

Localization for C19orf44 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C19orf44 gene
Compartment Confidence
nucleus 3
cytosol 3

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nuclear bodies (2)
  • Nucleus (2)
See all subcellular structures

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C19orf44 Gene

Pathways & Interactions for C19orf44 Gene

SuperPathways for C19orf44 Gene

No Data Available

Interacting Proteins for C19orf44 Gene

Gene Ontology (GO) - Biological Process for C19orf44 Gene


No data available for Pathways by source and SIGNOR curated interactions for C19orf44 Gene

Drugs & Compounds for C19orf44 Gene

No Compound Related Data Available

Transcripts for C19orf44 Gene

Unigene Clusters for C19orf44 Gene

Chromosome 19 open reading frame 44:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for C19orf44 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b · 7c ^ 8 ^ 9a · 9b ^ 10
SP3: -
SP4: - -

Relevant External Links for C19orf44 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C19orf44 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C19orf44 Gene

Protein differential expression in normal tissues from HIPED for C19orf44 Gene

This gene is overexpressed in Heart (39.1) and Lung (29.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C19orf44 Gene

Protein tissue co-expression partners for C19orf44 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of C19orf44 Gene:


SOURCE GeneReport for Unigene cluster for C19orf44 Gene:


Evidence on tissue expression from TISSUES for C19orf44 Gene

  • Nervous system(2.2)
genes like me logo Genes that share expression patterns with C19orf44: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for C19orf44 Gene

Orthologs for C19orf44 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C19orf44 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C19H19orf44 33
  • 99.31 (n)
C19orf44 34
  • 99 (a)
(Bos Taurus)
Mammalia C7H19orf44 33
  • 73.98 (n)
C19orf44 34
  • 59 (a)
(Canis familiaris)
Mammalia C20H19orf44 33
  • 73.77 (n)
C19orf44 34
  • 59 (a)
(Rattus norvegicus)
Mammalia RGD1311847 33
  • 66.84 (n)
(Mus musculus)
Mammalia 1700030K09Rik 33 16 34
  • 66.56 (n)
(Monodelphis domestica)
Mammalia C19orf44 34
  • 44 (a)
(Ornithorhynchus anatinus)
Mammalia C19orf44 34
  • 39 (a)
(Gallus gallus)
Aves C19orf44 34
  • 29 (a)
(Anolis carolinensis)
Reptilia C19orf44 34
  • 32 (a)
(Danio rerio)
Actinopterygii C22H19orf44 34
  • 27 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 33 (a)
Species where no ortholog for C19orf44 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C19orf44 Gene

Gene Tree for C19orf44 (if available)
Gene Tree for C19orf44 (if available)

Paralogs for C19orf44 Gene

No data available for Paralogs for C19orf44 Gene

Variants for C19orf44 Gene

Sequence variations from dbSNP and Humsavar for C19orf44 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1060502978 uncertain-significance, Familial hypertrophic cardiomyopathy 19 16,495,763(+) C/T upstream_transcript_variant
rs144355944 benign, Familial hypertrophic cardiomyopathy 19 16,495,848(+) A/G upstream_transcript_variant
rs149634686 benign, Familial hypertrophic cardiomyopathy 19 16,495,819(+) T/C upstream_transcript_variant
rs368506422 uncertain-significance, Primary dilated cardiomyopathy 16,496,063(+) A/T upstream_transcript_variant
rs370721650 benign, Familial hypertrophic cardiomyopathy 19 16,496,070(+) G/A/C/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for C19orf44 Gene

Variant ID Type Subtype PubMed ID
esv3370089 CNV insertion 20981092

Variation tolerance for C19orf44 Gene

Residual Variation Intolerance Score: 13.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.06; 21.62% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for C19orf44 Gene

Human Gene Mutation Database (HGMD)
SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C19orf44 Gene

Disorders for C19orf44 Gene

Additional Disease Information for C19orf44

No disorders were found for C19orf44 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C19orf44 Gene

Publications for C19orf44 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 58
  2. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  3. A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. (PMID: 26673895) Kırlı K … Görlich D (eLife 2015) 3 58
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3 58
  5. Toward a comprehensive characterization of a human cancer cell phosphoproteome. (PMID: 23186163) Zhou H … Mohammed S (Journal of proteome research 2013) 4 58

Products for C19orf44 Gene

Sources for C19orf44 Gene

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