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Aliases for C19orf38 Gene
Aliases for C19orf38 Gene
External Ids for C19orf38 Gene
- HGNC: 34073
- Entrez Gene: 255809
- Ensembl: ENSG00000214212
- UniProtKB: A8MVS5
Previous GeneCards Identifiers for C19orf38 Gene
- GC19P010821
- GC19P010961
- GC19P010537
- GC19P010947
Summaries for C19orf38 Gene
GeneCards Summary for C19orf38 Gene
C19orf38 (Chromosome 19 Open Reading Frame 38) is a Protein Coding gene.
Additional gene information for C19orf38 Gene
- HGNC(34073)
- Entrez Gene(255809)
- Ensembl(ENSG00000214212)
- UniProtKB(A8MVS5)
- Open Targets Platform(ENSG00000214212)
- Search for C19orf38 at DataMed
- Search for C19orf38 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for C19orf38 Gene
Genomics for C19orf38 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for C19orf38 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around C19orf38 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for C19orf38
- Top Transcription factor binding sites by QIAGEN in the C19orf38 gene promoter:
-
- AML1a
- Egr-3
- HOXA5
- LCR-F1
- MAZR
- NRSF form 2
- p53
- RORalpha1
- ZIC2
- ZID
Genomic Locations for C19orf38 Gene
Genomic Locations for C19orf38 Gene
- chr19:10,836,558-10,869,796
- (GRCh38/hg38)
- Size:
- 33,239 bases
- Orientation:
- Plus strand
- chr19:10,947,251-10,980,466
- (GRCh37/hg19)
- Size:
- 33,216 bases
- Orientation:
- Plus strand
Genomic View for C19orf38 Gene
Genes around C19orf38 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19p13.2 by HGNC
- 19p13.2 by Entrez Gene
- 19p13.2 by Ensembl
C19orf38 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for C19orf38 Gene
Proteins for C19orf38 Gene
-
Protein details for C19orf38 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- A8MVS5-HIDE1_HUMAN
- Recommended name:
- Protein HIDE1
- Protein Accession:
- A8MVS5
- B2RXI3
Protein attributes for C19orf38 Gene
- Size:
- 230 amino acids
- Molecular mass:
- 24753 Da
- Quaternary structure:
- No Data Available
Protein Expression for C19orf38 Gene
Post-translational modifications for C19orf38 Gene
Other Protein References for C19orf38 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Creative Diagnostics Anti-C19ORF38 (aa 136-167) polyclonal antibody
-
Custom Antibody ServicesOriGene Antibodies for C19orf38
- Invitrogen Antibodies for C19orf38 (AFLGC-C19orf38)
- antibodies-online: Show 9 available C19ORF38 Antibodies ranked by validation data
Protein Products
-
OriGene Purified Proteins for C19orf38
- Search Origene for MassSpec and Protein Over-expression Lysates for C19orf38
- Origene Custom Protein Services for C19orf38
No data available for DME Specific Peptides for C19orf38 Gene
Domains & Families for C19orf38 Gene
Gene Families for C19orf38 Gene
- Human Protein Atlas (HPA):
-
- Predicted membrane proteins
Protein Domains for C19orf38 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for C19orf38 Gene
- GenScript: Design optimal peptide antigens:
-
- Protein HIDE1 (HIDE1_HUMAN)
No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for C19orf38 Gene
Function for C19orf38 Gene
Phenotypes From GWAS Catalog for C19orf38 Gene
Phenotypes for C19orf38 Gene
- MGI mutant phenotypes for C19orf38:
- inferred from 1 alleles
Animal Models for C19orf38 Gene
- MGI Knock Outs for C19orf38:
-
- AB124611 AB124611<tm1.1(KOMP)Vlcg>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for C19orf38 - Select products 50% OFF >
- * C19orf38 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for C19orf38
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for C19orf38
-
Santa Cruz Biotechnology (SCBT) CRISPR for C19orf38
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for C19orf38
- Browse OriGene Inhibitory RNA Products For C19orf38
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C19orf38
Clone Products
- Applied Biological Materials (abm): Clones for C19orf38 - Select products 50% OFF >
- * C19orf38 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene ORF clones in human for C19orf38
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for C19orf38
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for C19orf38
Cell Line Products
-
Horizon Cell Lines for C19orf38
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for C19orf38 Gene
Localization for C19orf38 Gene
Subcellular locations from UniProtKB/Swiss-Prot for C19orf38 Gene
- Membrane. Single-pass type I membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 3 |
| extracellular | 2 |
| mitochondrion | 0 |
| lysosome | 0 |
- Cytosol (1)
- Golgi apparatus (1)
- Plasma membrane (1)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
Pathways & Interactions for C19orf38 Gene
Interacting Proteins for C19orf38 Gene
No data available for Pathways by source and SIGNOR curated interactions for C19orf38 Gene
Transcripts for C19orf38 Gene
mRNA/cDNA for C19orf38 Gene
- 1 REFSEQ mRNAs :
- 1 NCBI additional mRNA sequence :
- 3 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000592854 1060 nts (view in UCSC)
- ENST00000397820 1210 nts (view in UCSC)
- ENST00000587494 665 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for C19orf38 - Select products 50% OFF >
- * C19orf38 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for C19orf38
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for C19orf38
-
Santa Cruz Biotechnology (SCBT) CRISPR for C19orf38
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for C19orf38
- Browse OriGene Inhibitory RNA Products For C19orf38
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C19orf38
Clone Products
- Applied Biological Materials (abm): Clones for C19orf38 - Select products 50% OFF >
- * C19orf38 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene ORF clones in human for C19orf38
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for C19orf38
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for C19orf38
Relevant External Links for C19orf38 Gene
- GeneLoc Exon Structure for
- C19orf38
Expression for C19orf38 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Lateral Plate Mesoderm (Gastrulation Derivatives)
- Hematopoietic Stem Cells Aorta-Gonad-Mesonephros
-
Blood (Cardiovascular System)
- Hematopoietic Stem Cells Aorta-Gonad-Mesonephros
mRNA differential expression in normal tissues according to GTEx for C19orf38 Gene
This gene is overexpressed in Whole Blood (x41.7).
This gene is overexpressed in Monocytes (35.9), Testis (19.9), and Peripheral blood mononuclear cells (8.1).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C19orf38 Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for C19orf38
SOURCE GeneReport for Unigene cluster for C19orf38 Gene:
Hs.440535Primer Products
Gene Expression Assay Products
No data available for mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C19orf38 Gene
Orthologs for C19orf38 Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | C19orf38 31 |
|
OneToOne | |
| C19H19orf38 30 |
|
||||
| Dog (Canis familiaris) |
Mammalia | C20H19orf38 30 |
|
||
| C19orf38 31 |
|
OneToOne | |||
| Cow (Bos Taurus) |
Mammalia | C7H19orf38 30 |
|
||
| C19orf38 31 |
|
OneToOne | |||
| Mouse (Mus musculus) |
Mammalia | AB124611 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | LOC691141 30 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | C19orf38 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | C19orf38 31 |
|
OneToOne |
- Species where no ortholog for C19orf38 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
- Zebrafish (Danio rerio)
Paralogs for C19orf38 Gene
No data available for Paralogs for C19orf38 Gene
Variants for C19orf38 Gene
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3583244 | CNV | loss | 25503493 |
| esv3643659 | CNV | loss | 21293372 |
| nsv1123220 | CNV | deletion | 24896259 |
| nsv1160584 | CNV | deletion | 26073780 |
| nsv2416 | CNV | insertion | 18451855 |
| nsv833748 | CNV | loss | 17160897 |
Gene Damage Index Score:
4.05;
60.64% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for C19orf38 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- C19orf38
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for C19orf38 Gene
Disorders for C19orf38 Gene
Additional Disease Information for C19orf38
- Genetic Association Database
- (GAD)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No disorders were found for C19orf38 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C19orf38 Gene
Publications for C19orf38 Gene
- The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J … Lucas SM (Nature 2004) 3 4
- A reference map of the human binary protein interactome. (PMID: 32296183) Luck K … Calderwood MA (Nature 2020) 3
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3
ExternalLinks
Products for C19orf38 Gene
- Custom Antibody ServicesOriGene Antibodies for C19orf38
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for C19orf38
- Search Origene for MassSpec and Protein Over-expression Lysates for C19orf38
- Origene Custom Protein Services for C19orf38
- Origene shrna, sirna, and RNAi products in human, mouse, rat for C19orf38
- Browse OriGene Inhibitory RNA Products For C19orf38
- Browse OriGene qPCR primer pairs and template standards
- OriGene CRISPR knockouts for C19orf38
- OriGene ORF clones in human for C19orf38
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For C19orf38
- Sino Biological Human cDNA Clone for C19orf38
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Invitrogen Antibodies for C19orf38 (AFLGC-C19orf38)
- VectorBuilder Custom and pre-made DNA vectors for C19orf38 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for C19orf38 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for C19orf38 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for C19orf38 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for C19orf38
- antibodies-online: Show 9 available C19ORF38 Antibodies ranked by validation data
- antibodies-online: Search results for available C19ORF38 related products ranked by validation data
- antibodies-online: Search results for available C19ORF38 related products ranked by validation data
- Horizon Cell Lines for C19orf38
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for C19orf38
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for C19orf38
- Search GeneCopoeia for miRNA 3'UTR Target clone products for C19orf38
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C19orf38
Sources for C19orf38 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB