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Aliases for C19orf24 Gene

Aliases for C19orf24 Gene

  • Chromosome 19 Open Reading Frame 24 2 3 5
  • Uncharacterized Membrane Protein C19orf24 3 4

External Ids for C19orf24 Gene

Previous GeneCards Identifiers for C19orf24 Gene

  • GC19P001228
  • GC19P001229
  • GC19P001049
  • GC19P001276
  • GC19P001278
  • GC19P001282
  • GC19P001289
  • GC19P001292
  • GC19P001294
  • GC19P001325
  • GC19P001302
  • GC19P001304
  • GC19P001309
  • GC19P001311
  • GC19P001313
  • GC19P001315
  • GC19P001318
  • GC19P001322

Summaries for C19orf24 Gene

GeneCards Summary for C19orf24 Gene

C19orf24 (Chromosome 19 Open Reading Frame 24) is a Protein Coding gene.

Additional gene information for C19orf24 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C19orf24 Gene

Genomics for C19orf24 Gene

GeneHancer (GH) Regulatory Elements for C19orf24 Gene

Promoters and enhancers for C19orf24 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J001236 Promoter/Enhancer 2.7 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 645.9 -18.7 -18718 41.2 HDGF MTA3 SP1 ZFX CC2D1A ZNF652 ELF3 CTCF MNT SIX5 CIRBP C19orf24 MIDN CBARP ATP5F1D SF3A2 TMEM259 TCF3 LOC100288123 DAZAP1
GH19J001278 Promoter 0.7 EPDnew 600.7 +3.3 3254 0.1 ZNF692 HIC1 C19orf24 EFNA2
GH19J001382 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE dbSUPER 21.1 +108.6 108580 3 ZNF473 ZFX SP1 ELF3 MNT SIX5 CBFA2T2 ZNF148 NKRF MLLT1 PIR43938 NDUFS7 PIR60228 TRF-GAA1-6 TRN-GTT2-6 CIRBP SF3A2 TMEM259 DAZAP1 LOC100288123
GH19J001437 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 21.1 +164.0 163962 4.3 HDGF ZFX SP1 CC2D1A CTCF ELF3 ZKSCAN8 MNT NKRF POLR2A RPS15 ENSG00000268798 SF3A2 TMEM259 TCF3 LOC100288123 DAZAP1 GRIN3B PTBP1 ENSG00000267317
GH19J001442 Promoter/Enhancer 2.5 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 13 +169.2 169235 4.1 ZFX CTCF ELF3 CBFA2T2 NKRF POLR2A ZNF121 ZNF384 ZSCAN21 AHR APC2 SF3A2 C19orf24 DAZAP1 C19orf25 PCSK4 REEP6 CIRBP GRIN3B SCAMP4
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around C19orf24 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the C19orf24 gene promoter:
  • AP-1
  • Chx10
  • GR
  • GR-alpha
  • NF-kappaB
  • NF-kappaB1
  • p53
  • Pax-4a
  • Sox9

Genomic Locations for C19orf24 Gene

Genomic Locations for C19orf24 Gene
3,724 bases
Plus strand
4,223 bases
Plus strand

Genomic View for C19orf24 Gene

Genes around C19orf24 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C19orf24 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C19orf24 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C19orf24 Gene

Proteins for C19orf24 Gene

  • Protein details for C19orf24 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized membrane protein C19orf24
    Protein Accession:
    Secondary Accessions:
    • Q9NWS2

    Protein attributes for C19orf24 Gene

    132 amino acids
    Molecular mass:
    14249 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAA91305.1; Type=Miscellaneous discrepancy; Evidence={ECO:0000305};

neXtProt entry for C19orf24 Gene

Post-translational modifications for C19orf24 Gene

  • Glycosylation at isoforms=47
  • Modification sites at PhosphoSitePlus

Other Protein References for C19orf24 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C19orf24 Gene

Domains & Families for C19orf24 Gene

Gene Families for C19orf24 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Predicted membrane proteins

Protein Domains for C19orf24 Gene


Suggested Antigen Peptide Sequences for C19orf24 Gene

GenScript: Design optimal peptide antigens:
  • Uncharacterized membrane protein C19orf24 (CS024_HUMAN)
  • Chromosome 19 open reading frame 24, isoform CRA_a (D6W5Y7_HUMAN)

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C19orf24: view

No data available for UniProtKB/Swiss-Prot for C19orf24 Gene

Function for C19orf24 Gene

Phenotypes From GWAS Catalog for C19orf24 Gene

genes like me logo Genes that share phenotypes with C19orf24: view

Animal Model Products

CRISPR Products

Clone Products

  • Applied Biological Materials (abm): Clones for C19orf24 - Now 50% OFF >
  • * C19orf24 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
  • * C19orf24 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C19orf24 Gene

Localization for C19orf24 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C19orf24 Gene

Membrane; Single-pass type I membrane protein.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C19orf24 gene
Compartment Confidence
extracellular 5
nucleus 2
golgi apparatus 2
cytosol 1
plasma membrane 0

Subcellular locations from the

Human Protein Atlas (HPA)
  • Golgi apparatus (2)
  • Nuclear speckles (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for C19orf24 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IDA 16847563
GO:0005737 cytoplasm IDA 16847563
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with C19orf24: view

Pathways & Interactions for C19orf24 Gene

PathCards logo

SuperPathways for C19orf24 Gene

No Data Available

Interacting Proteins for C19orf24 Gene

Gene Ontology (GO) - Biological Process for C19orf24 Gene


No data available for Pathways by source and SIGNOR curated interactions for C19orf24 Gene

Drugs & Compounds for C19orf24 Gene

No Compound Related Data Available

Transcripts for C19orf24 Gene

mRNA/cDNA for C19orf24 Gene

Unigene Clusters for C19orf24 Gene

Chromosome 19 open reading frame 24:
Representative Sequences:

CRISPR Products

Clone Products

  • Applied Biological Materials (abm): Clones for C19orf24 - Now 50% OFF >
  • * C19orf24 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
  • * C19orf24 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All

Alternative Splicing Database (ASD) splice patterns (SP) for C19orf24 Gene

No ASD Table

Relevant External Links for C19orf24 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C19orf24 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C19orf24 Gene

NURSA nuclear receptor signaling pathways regulating expression of C19orf24 Gene:


SOURCE GeneReport for Unigene cluster for C19orf24 Gene:

genes like me logo Genes that share expression patterns with C19orf24: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C19orf24 Gene

Orthologs for C19orf24 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C19orf24 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C19orf24 35
  • 98 (a)
C19H19orf24 34
  • 95.2 (n)
(Canis familiaris)
Mammalia C19orf24 35
  • 88 (a)
(Bos Taurus)
Mammalia C7H19orf24 35 34
  • 81.13 (n)
(Mus musculus)
Mammalia 1600002K03Rik 17 35 34
  • 69.18 (n)
(Rattus norvegicus)
Mammalia RGD1562114 34
  • 66.67 (n)
Species where no ortholog for C19orf24 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C19orf24 Gene

Gene Tree for C19orf24 (if available)
Gene Tree for C19orf24 (if available)

Paralogs for C19orf24 Gene

No data available for Paralogs for C19orf24 Gene

Variants for C19orf24 Gene

Sequence variations from dbSNP and Humsavar for C19orf24 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000091381 -- 1,277,843(+) C/G intron_variant
rs1000099801 -- 1,275,516(+) A/ upstream_transcript_variant
rs1000401424 -- 1,275,592(+) C/T coding_sequence_variant, synonymous_variant
rs1000465668 -- 1,279,332(+) G/T downstream_transcript_variant
rs1000754597 -- 1,279,525(+) C/T downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for C19orf24 Gene

Variant ID Type Subtype PubMed ID
dgv136n111 CNV deletion 26073780
esv1779341 CNV insertion 17803354
esv2758743 CNV gain+loss 17122850
esv3368458 CNV duplication 20981092
esv3395739 CNV insertion 20981092
esv3643389 CNV gain 21293372
esv3643390 CNV loss 21293372
esv3643391 CNV gain 21293372
esv990677 CNV insertion 20482838
nsv1055164 CNV gain 25217958
nsv1058677 CNV loss 25217958
nsv1060536 CNV gain 25217958
nsv1143898 CNV deletion 24896259
nsv1160555 CNV deletion 26073780
nsv138017 CNV insertion 16902084
nsv470103 CNV gain 18288195
nsv470104 CNV loss 18288195
nsv953941 CNV deletion 24416366
nsv9662 CNV gain 18304495

Variation tolerance for C19orf24 Gene

Gene Damage Index Score: 0.57; 12.22% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for C19orf24 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C19orf24 Gene

Disorders for C19orf24 Gene

Additional Disease Information for C19orf24

No disorders were found for C19orf24 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C19orf24 Gene

Publications for C19orf24 Gene

  1. A novel recently evolved gene C19orf24 encodes a non-classical secreted protein. (PMID: 16847563) Wang XR … Han ZG (Cellular & molecular biology letters 2006) 2 3 58
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3 58
  5. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PMID: 20068231) Olsen JV … Mann M (Science signaling 2010) 4 58

Products for C19orf24 Gene

Sources for C19orf24 Gene

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