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Aliases for C18orf12 Gene

Aliases for C18orf12 Gene

  • Chromosome 18 Open Reading Frame 12 2 3 5
  • Uncharacterized Protein C18orf12 3 4
  • Protein HEIL1 4
  • HsT2508 3
  • HEIL1 3

External Ids for C18orf12 Gene

Previous GeneCards Identifiers for C18orf12 Gene

  • GC18P044030
  • GC18U900187
  • GC18P045778

Summaries for C18orf12 Gene

GeneCards Summary for C18orf12 Gene

C18orf12 (Chromosome 18 Open Reading Frame 12) is a Protein Coding gene.

Additional gene information for C18orf12 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C18orf12 Gene

Genomics for C18orf12 Gene

GeneHancer (GH) Regulatory Elements for C18orf12 Gene

Promoters and enhancers for C18orf12 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH18J048254 Enhancer 0.5 Ensembl 0.7 +3.8 3805 3.8 RBAK FOXA2 ZNF26 ZNF507 L3MBTL2 C18orf12 ZBTB7C
GH18J048264 Enhancer 0.7 Ensembl ENCODE 0.4 +12.2 12219 1.4 MAFK RFX1 ZNF316 MAFG MAFF EMSY C18orf12 ZBTB7C
GH18J048239 Enhancer 0.5 Ensembl ENCODE 0.4 -13.6 -13568 1.2 EGR2 GC18P048237 C18orf12 ZBTB7C
GH18J048408 Promoter/Enhancer 1.8 EPDnew Ensembl ENCODE 0.1 +157.0 157005 3.4 ZSCAN21 SP7 KLF14 PRDM1 GLIS2 PKNOX1 ZBTB8A ZNF600 PRDM10 ZIC2 ZBTB7C C18orf12
GH18J048308 Enhancer 0.8 Ensembl ENCODE 0.2 +56.0 56004 0.6 NFIB MYC CTBP1 ZNF217 DPF2 GATA3 MAZ ZNF687 SMARCE1 C18orf12 ZBTB7C
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around C18orf12 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the C18orf12 gene promoter:
  • ATF
  • ATF-2
  • C/EBPalpha
  • Cart-1
  • CREB
  • CUTL1
  • HNF-1
  • HNF-1A
  • Nkx2-5

Genomic Locations for C18orf12 Gene

Genomic Locations for C18orf12 Gene
chr18:48,252,296-48,252,837
(GRCh38/hg38)
Size:
542 bases
Orientation:
Plus strand
chr18:45,778,672-45,779,208
(GRCh37/hg19)
Size:
537 bases
Orientation:
Plus strand

Genomic View for C18orf12 Gene

Genes around C18orf12 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C18orf12 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C18orf12 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C18orf12 Gene

Proteins for C18orf12 Gene

  • Protein details for C18orf12 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96KH6-CR012_HUMAN
    Recommended name:
    Uncharacterized protein C18orf12
    Protein Accession:
    Q96KH6

    Protein attributes for C18orf12 Gene

    Size:
    178 amino acids
    Molecular mass:
    19680 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C18orf12 Gene

Post-translational modifications for C18orf12 Gene

No Post-translational modifications

Other Protein References for C18orf12 Gene

REFSEQ proteins:

No data available for DME Specific Peptides for C18orf12 Gene

Domains & Families for C18orf12 Gene

Protein Domains for C18orf12 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for C18orf12 Gene

GenScript: Design optimal peptide antigens:
  • Protein HEIL1 (CR012_HUMAN)

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C18orf12: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C18orf12 Gene

Function for C18orf12 Gene

Phenotypes From GWAS Catalog for C18orf12 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C18orf12 Gene

Localization for C18orf12 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for C18orf12 Gene

Pathways & Interactions for C18orf12 Gene

PathCards logo

SuperPathways for C18orf12 Gene

No Data Available

Interacting Proteins for C18orf12 Gene

Gene Ontology (GO) - Biological Process for C18orf12 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C18orf12 Gene

Drugs & Compounds for C18orf12 Gene

No Compound Related Data Available

Transcripts for C18orf12 Gene

mRNA/cDNA for C18orf12 Gene

(2) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Unigene Clusters for C18orf12 Gene

Chromosome 18 open reading frame 12:
Representative Sequences:

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for C18orf12 Gene

No ASD Table

Relevant External Links for C18orf12 Gene

GeneLoc Exon Structure for
C18orf12
ECgene alternative splicing isoforms for
C18orf12

Expression for C18orf12 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C18orf12 Gene

mRNA differential expression in normal tissues according to GTEx for C18orf12 Gene

This gene is overexpressed in Testis (x42.6), Cervix - Endocervix (x5.3), and Nerve - Tibial (x5.1).

NURSA nuclear receptor signaling pathways regulating expression of C18orf12 Gene:

C18orf12

SOURCE GeneReport for Unigene cluster for C18orf12 Gene:

Hs.334493
genes like me logo Genes that share expression patterns with C18orf12: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C18orf12 Gene

Orthologs for C18orf12 Gene

Evolution for C18orf12 Gene

ENSEMBL:
Gene Tree for C18orf12 (if available)
TreeFam:
Gene Tree for C18orf12 (if available)

No data available for Orthologs for C18orf12 Gene

Paralogs for C18orf12 Gene

No data available for Paralogs for C18orf12 Gene

Variants for C18orf12 Gene

Sequence variations from dbSNP and Humsavar for C18orf12 Gene

SNP ID Clin Chr 18 pos Variation AA Info Type
rs1001393065 -- 48,251,778(+) A/G upstream_transcript_variant
rs1003312798 -- 48,251,552(+) C/T upstream_transcript_variant
rs1003596373 -- 48,250,607(+) A/C upstream_transcript_variant
rs1004137374 -- 48,250,401(+) C/T upstream_transcript_variant
rs1007218115 -- 48,250,617(+) C/A upstream_transcript_variant

Additional Variant Information for C18orf12 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C18orf12

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for C18orf12 Gene

Disorders for C18orf12 Gene

Additional Disease Information for C18orf12

No disorders were found for C18orf12 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C18orf12 Gene

Publications for C18orf12 Gene

  1. Genome-wide association study in Han Chinese identifies three novel loci for human height. (PMID: 23456168) Hao Y … Gu D (Human genetics 2013) 3 58

Products for C18orf12 Gene

Sources for C18orf12 Gene

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