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Aliases for C17orf82 Gene

Aliases for C17orf82 Gene

  • Chromosome 17 Open Reading Frame 82 2 3 5

External Ids for C17orf82 Gene

Previous GeneCards Identifiers for C17orf82 Gene

  • GC17P056844
  • GC17P059489

Summaries for C17orf82 Gene

GeneCards Summary for C17orf82 Gene

C17orf82 (Chromosome 17 Open Reading Frame 82) is a Protein Coding gene.

Additional gene information for C17orf82 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C17orf82 Gene

Genomics for C17orf82 Gene

GeneHancer (GH) Regulatory Elements for C17orf82 Gene

Promoters and enhancers for C17orf82 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17I060523 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 9.8 -886.3 -886250 3.4 HDGF PKNOX1 SMAD1 MLX ARNT ZFP64 ARID4B SIN3A DMAP1 ZNF2 APPBP2 ENSG00000259349 TBX2-AS1 C17orf82 CLTC GC17P060514
GH17I061334 Enhancer 1.4 Ensembl ENCODE dbSUPER 9.9 -76.0 -75986 2.3 FOXA2 MLX ARID4B FEZF1 DMAP1 ZNF2 YY1 SLC30A9 ZNF213 FOS GC17P061333 INTS2 APPBP2 PPM1D TBX2-AS1 MED13 NACA2 C17orf82 ENSG00000273982 BCAS3
GH17I061567 Enhancer 1.1 ENCODE dbSUPER 11.8 +157.3 157294 3.9 FOXA2 SIN3A ETS1 SLC30A9 ATF7 FOS SP5 REST PPARG KAT8 NACA2 C17orf82 INTS2 TBX4 TBX2 ENSG00000267137
GH17I061195 Enhancer 1.2 UCNEbase Ensembl ENCODE dbSUPER 10.1 -215.4 -215409 0.9 COPS2 NR2F2 CHD2 TBX2-AS1 C17orf82 GC17P061246 GC17P061247 GC17M061120 BCAS3
GH17I061574 Enhancer 0.7 ENCODE 11.8 +163.3 163294 0.2 GATAD2A CTCF ZNF654 FOXA2 SAP130 TEAD1 ARID4B REST RAD21 RFX5 C17orf82 TBX4 TBX2 NACA2 ENSG00000267137
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around C17orf82 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the C17orf82 gene promoter:

Genomic Locations for C17orf82 Gene

Genomic Locations for C17orf82 Gene
chr17:61,411,751-61,413,280
(GRCh38/hg38)
Size:
1,530 bases
Orientation:
Plus strand
chr17:59,489,112-59,490,641
(GRCh37/hg19)

Genomic View for C17orf82 Gene

Genes around C17orf82 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C17orf82 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C17orf82 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C17orf82 Gene

Proteins for C17orf82 Gene

  • Protein details for C17orf82 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q86X59-CQ082_HUMAN
    Recommended name:
    Putative uncharacterized protein C17orf82
    Protein Accession:
    Q86X59

    Protein attributes for C17orf82 Gene

    Size:
    251 amino acids
    Molecular mass:
    25393 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C17orf82 Gene

Post-translational modifications for C17orf82 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C17orf82 Gene

REFSEQ proteins:

No data available for DME Specific Peptides for C17orf82 Gene

Domains & Families for C17orf82 Gene

Protein Domains for C17orf82 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C17orf82: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C17orf82 Gene

Function for C17orf82 Gene

Phenotypes From GWAS Catalog for C17orf82 Gene

Gene Ontology (GO) - Molecular Function for C17orf82 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with C17orf82: view

Phenotypes for C17orf82 Gene

genes like me logo Genes that share phenotypes with C17orf82: view

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C17orf82 Gene

Localization for C17orf82 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C17orf82 gene
Compartment Confidence
nucleus 3
cytosol 2
extracellular 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for C17orf82 Gene

Pathways & Interactions for C17orf82 Gene

SuperPathways for C17orf82 Gene

No Data Available

Interacting Proteins for C17orf82 Gene

Gene Ontology (GO) - Biological Process for C17orf82 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C17orf82 Gene

Drugs & Compounds for C17orf82 Gene

No Compound Related Data Available

Transcripts for C17orf82 Gene

mRNA/cDNA for C17orf82 Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(4) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C17orf82 Gene

Chromosome 17 open reading frame 82:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for C17orf82 Gene

No ASD Table

Relevant External Links for C17orf82 Gene

GeneLoc Exon Structure for
C17orf82
ECgene alternative splicing isoforms for
C17orf82

Expression for C17orf82 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C17orf82 Gene

Protein differential expression in normal tissues from HIPED for C17orf82 Gene

This gene is overexpressed in Bone (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C17orf82 Gene



Protein tissue co-expression partners for C17orf82 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of C17orf82 Gene:

C17orf82

SOURCE GeneReport for Unigene cluster for C17orf82 Gene:

Hs.434459
genes like me logo Genes that share expression patterns with C17orf82: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C17orf82 Gene

Orthologs for C17orf82 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for C17orf82 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C17H17orf82 33
  • 98.78 (n)
Species where no ortholog for C17orf82 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C17orf82 Gene

ENSEMBL:
Gene Tree for C17orf82 (if available)
TreeFam:
Gene Tree for C17orf82 (if available)

Paralogs for C17orf82 Gene

No data available for Paralogs for C17orf82 Gene

Variants for C17orf82 Gene

Sequence variations from dbSNP and Humsavar for C17orf82 Gene

SNP ID Clin Chr 17 pos Variation AA Info Type
rs1000505086 -- 61,413,173(+) T/C 3_prime_UTR_variant
rs1000599579 -- 61,413,606(+) C/A/T downstream_transcript_variant
rs1001157095 -- 61,411,059(+) A/G upstream_transcript_variant
rs1001228398 -- 61,411,604(+) C/T upstream_transcript_variant
rs1001813902 -- 61,410,145(+) A/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for C17orf82 Gene

Variant ID Type Subtype PubMed ID
dgv43n68 CNV loss 17160897
nsv518130 CNV gain 19592680
nsv952350 CNV deletion 24416366

Variation tolerance for C17orf82 Gene

Residual Variation Intolerance Score: 95.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.19; 75.93% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for C17orf82 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C17orf82

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C17orf82 Gene

Disorders for C17orf82 Gene

Additional Disease Information for C17orf82

No disorders were found for C17orf82 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C17orf82 Gene

Publications for C17orf82 Gene

  1. Identification of 15 loci influencing height in a Korean population. (PMID: 19893584) Kim JJ … Lee JK (Journal of human genetics 2010) 3 44 58
  2. Phospho-tyrosine dependent protein-protein interaction network. (PMID: 25814554) Grossmann A … Stelzl U (Molecular systems biology 2015) 3 58
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin EL … Gygi SP (Cell 2015) 3 58
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3 58
  5. Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. (PMID: 23263486) Köttgen A … Gieger C (Nature genetics 2013) 3 58

Products for C17orf82 Gene

Sources for C17orf82 Gene

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