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Aliases for C17orf78 Gene
Aliases for C17orf78 Gene
External Ids for C17orf78 Gene
- HGNC: 26831
- Entrez Gene: 284099
- Ensembl: ENSG00000278505
- UniProtKB: Q8N4C9
Previous GeneCards Identifiers for C17orf78 Gene
- GC17P032808
- GC17P035732
- GC17P031670
Summaries for C17orf78 Gene
GeneCards Summary for C17orf78 Gene
C17orf78 (Chromosome 17 Open Reading Frame 78) is a Protein Coding gene.
Additional gene information for C17orf78 Gene
- HGNC(26831)
- Entrez Gene(284099)
- Ensembl(ENSG00000278505)
- UniProtKB(Q8N4C9)
- Open Targets Platform(ENSG00000278505)
- Search for C17orf78 at DataMed
- Search for C17orf78 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for C17orf78 Gene
Genomics for C17orf78 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for C17orf78 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around C17orf78 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for C17orf78
- Top Transcription factor binding sites by QIAGEN in the C17orf78 gene promoter:
-
- AP-1
- ATF-2
- c-Jun
- C/EBPbeta
- Cart-1
- CREB
- deltaCREB
- E2F
- E2F-1
- GATA-2
Genomic Locations for C17orf78 Gene
Genomic Locations for C17orf78 Gene
- chr17:37,375,332-37,392,708
- (GRCh38/hg38)
- Size:
- 17,377 bases
- Orientation:
- Plus strand
- chr17:35,732,928-35,749,662
- (GRCh37/hg19)
- Size:
- 16,735 bases
- Orientation:
- Plus strand
Genomic View for C17orf78 Gene
Genes around C17orf78 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 17q12 by HGNC
- 17q12 by Entrez Gene
- 17q12 by Ensembl
C17orf78 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for C17orf78 Gene
Proteins for C17orf78 Gene
-
Protein details for C17orf78 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8N4C9-CQ078_HUMAN
- Recommended name:
- Uncharacterized protein C17orf78
- Protein Accession:
- Q8N4C9
- Q8N8D2
Protein attributes for C17orf78 Gene
- Size:
- 275 amino acids
- Molecular mass:
- 30555 Da
- Quaternary structure:
- No Data Available
Post-translational modifications for C17orf78 Gene
Other Protein References for C17orf78 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for C17orf78
- Novus Biologicals Antibodies for C17orf78
- Invitrogen Antibodies for C17orf78 (AFLGC-C17orf78)
- antibodies-online: Show 3 available C17orf78 Antibodies ranked by validation data
-
Biorbyt antibodies for C17orf78
Protein Products
-
OriGene Purified Proteins for C17orf78
- Search Origene for MassSpec and Protein Over-expression Lysates for C17orf78
- Origene Custom Protein Services for C17orf78
- Novus Biologicals lysates for C17orf78
No data available for DME Specific Peptides for C17orf78 Gene
Domains & Families for C17orf78 Gene
Gene Families for C17orf78 Gene
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Predicted membrane proteins
No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for C17orf78 Gene
Function for C17orf78 Gene
Phenotypes From GWAS Catalog for C17orf78 Gene
Phenotypes for C17orf78 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for C17orf78 - Select products 50% OFF >
- * C17orf78 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for C17orf78
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for C17orf78
-
Santa Cruz Biotechnology (SCBT) CRISPR for C17orf78
miRNA for C17orf78 Gene
- miRTarBase miRNAs that target C17orf78
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for C17orf78
- Browse OriGene Inhibitory RNA Products For C17orf78
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C17orf78
Clone Products
- Applied Biological Materials (abm): Clones for C17orf78 - Select products 50% OFF >
- * C17orf78 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene ORF clones in human for C17orf78
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for C17orf78
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for C17orf78
Cell Line Products
-
Horizon Cell Lines for C17orf78
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C17orf78 Gene
Localization for C17orf78 Gene
Subcellular locations from UniProtKB/Swiss-Prot for C17orf78 Gene
- Membrane. Single-pass membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 2 |
| extracellular | 1 |
| cytosol | 1 |
| cytoskeleton | 0 |
| mitochondrion | 0 |
| peroxisome | 0 |
| nucleus | 0 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for C17orf78 Gene
Transcripts for C17orf78 Gene
mRNA/cDNA for C17orf78 Gene
- 2 REFSEQ mRNAs :
- 3 NCBI additional mRNA sequence :
- 2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000611038 1675 nts (view in UCSC)
- ENST00000615133 1920 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for C17orf78 - Select products 50% OFF >
- * C17orf78 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for C17orf78
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for C17orf78
-
Santa Cruz Biotechnology (SCBT) CRISPR for C17orf78
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for C17orf78
- Browse OriGene Inhibitory RNA Products For C17orf78
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C17orf78
Clone Products
- Applied Biological Materials (abm): Clones for C17orf78 - Select products 50% OFF >
- * C17orf78 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene ORF clones in human for C17orf78
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for C17orf78
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for C17orf78
Relevant External Links for C17orf78 Gene
- GeneLoc Exon Structure for
- C17orf78
Expression for C17orf78 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
mRNA differential expression in normal tissues according to GTEx for C17orf78 Gene
This gene is overexpressed in Small Intestine - Terminal Ileum (x44.0).
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for C17orf78
SOURCE GeneReport for Unigene cluster for C17orf78 Gene:
Hs.439154Evidence on tissue expression from TISSUES for C17orf78 Gene
- Intestine(4.4)
Primer Products
-
OriGene qPCR primer pairs for C17orf78
Gene Expression Assay Products
No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for C17orf78 Gene
Orthologs for C17orf78 Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | C17H17orf78 30 |
|
||
| Dog (Canis familiaris) |
Mammalia | C9H17orf78 30 |
|
||
| Cow (Bos Taurus) |
Mammalia | C19H17orf78 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Gm11437 30 17 |
|
||
| Rat (Rattus norvegicus) |
Mammalia | LOC102552988 30 |
|
- Species where no ortholog for C17orf78 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Oppossum (Monodelphis domestica)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
- Zebrafish (Danio rerio)
Paralogs for C17orf78 Gene
No data available for Paralogs for C17orf78 Gene
Variants for C17orf78 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for C17orf78 Gene
| SNP ID | Clinical significance and condition | Chr 17 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1714987 | - | p.Thr152Ser |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv3157n100 | CNV | gain | 25217958 |
| esv2667392 | CNV | deletion | 23128226 |
| esv2758687 | CNV | gain | 17122850 |
| esv32692 | CNV | loss | 17666407 |
| esv3640487 | CNV | gain | 21293372 |
| esv3640489 | CNV | loss | 21293372 |
| nsv574928 | CNV | loss | 21841781 |
Residual Variation Intolerance Score:
64.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
5.28;
70.36% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for C17orf78 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- C17orf78
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C17orf78 Gene
Disorders for C17orf78 Gene
Additional Disease Information for C17orf78
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No disorders were found for C17orf78 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C17orf78 Gene
Publications for C17orf78 Gene
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 2 3 4
- Genome-wide association study of celiac disease in North America confirms FRMD4B as new celiac locus. (PMID: 24999842) Garner C … Neuhausen SL (PloS one 2014) 3
- GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer. (PMID: 23535730) Pharoah PD … Sellers TA (Nature genetics 2013) 3
- Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey SD … DREAM investigators (Diabetes care 2010) 3
- Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. (PMID: 19913121) Talmud PJ … BRIGHT Consortium (American journal of human genetics 2009) 3
ExternalLinks
Products for C17orf78 Gene
- Custom Antibody ServicesOriGene Antibodies for C17orf78
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for C17orf78
- Search Origene for MassSpec and Protein Over-expression Lysates for C17orf78
- Origene Custom Protein Services for C17orf78
- Origene shrna, sirna, and RNAi products in human, mouse, rat for C17orf78
- Browse OriGene Inhibitory RNA Products For C17orf78
- OriGene qPCR primer pairs for C17orf78
- OriGene CRISPR knockouts for C17orf78
- OriGene ORF clones in human for C17orf78
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For C17orf78
- Sino Biological Human cDNA Clone for C17orf78
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for C17orf78
- Novus Biologicals lysates for C17orf78
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Invitrogen Antibodies for C17orf78 (AFLGC-C17orf78)
- VectorBuilder Custom and pre-made DNA vectors for C17orf78 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for C17orf78 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for C17orf78 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for C17orf78 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for C17orf78
- antibodies-online: Show 3 available C17orf78 Antibodies ranked by validation data
- antibodies-online: Search results for available C17orf78 related products ranked by validation data
- antibodies-online: Search results for available C17orf78 related products ranked by validation data
- Horizon Cell Lines for C17orf78
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for C17orf78
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for C17orf78
- Search GeneCopoeia for miRNA 3'UTR Target clone products for C17orf78
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C17orf78
- Biorbyt antibodies for C17orf78
Sources for C17orf78 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB