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Aliases for C17orf77 Gene
Aliases for C17orf77 Gene
External Ids for C17orf77 Gene
- HGNC: 26480
- Entrez Gene: 146723
- Ensembl: ENSG00000182352
- UniProtKB: Q96MU5
Previous GeneCards Identifiers for C17orf77 Gene
- GC17P070093
- GC17P072581
- GC17P067990
- GC17P074586
Summaries for C17orf77 Gene
GeneCards Summary for C17orf77 Gene
C17orf77 (Chromosome 17 Open Reading Frame 77) is a Protein Coding gene.
Additional gene information for C17orf77 Gene
No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for C17orf77 Gene
Genomics for C17orf77 Gene
GeneHancer (GH) Regulatory Elements for C17orf77 Gene
Promoters and enhancers for C17orf77 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH17J074593 | Promoter | 0.3 | EPDnew | 0.4 | +7.6 | 7608 | 0.1 | CD300LD C17orf77 ENSG00000261222 LOC101928343 | ||
| GH17J074592 | Promoter | 0.3 | Ensembl | 0.4 | +7.4 | 7422 | 0.2 | CD300LD SUMO2 C17orf77 piR-51845-001 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around C17orf77 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the C17orf77 gene promoter:
-
- AML1a
- AREB6
- Bach1
- FOXF2
- HNF-4alpha1
- HNF-4alpha2
- LCR-F1
- SRF
- SRF (504 AA)
- USF1
Genomic Locations for C17orf77 Gene
Genomic Locations for C17orf77 Gene
- chr17:74,584,679-74,594,209
- (GRCh38/hg38)
- Size:
- 9,531 bases
- Orientation:
- Plus strand
- chr17:72,580,818-72,590,348
- (GRCh37/hg19)
- Size:
- 9,531 bases
- Orientation:
- Plus strand
Genomic View for C17orf77 Gene
Genes around C17orf77 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 17q25.1 by HGNC
- 17q25.1 by Entrez Gene
- 17q25.1 by Ensembl
C17orf77 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for C17orf77 Gene
Proteins for C17orf77 Gene
-
Protein details for C17orf77 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q96MU5-CQ077_HUMAN
- Recommended name:
- Uncharacterized protein C17orf77
- Protein Accession:
- Q96MU5
Protein attributes for C17orf77 Gene
- Size:
- 243 amino acids
- Molecular mass:
- 26264 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=AK056444; Type=Erroneous termination; Positions=207; Note=Translated as Cys.; Evidence={ECO:0000305};
Post-translational modifications for C17orf77 Gene
Other Protein References for C17orf77 Gene
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for C17orf77
- antibodies-online: Show 18 available C17ORF77 Antibodies ranked by validation data
Protein Products
-
OriGene Purified Proteins for C17orf77
- Search Origene for MassSpec and Protein Over-expression Lysates for C17orf77
- Origene Custom Protein Services for C17orf77
- Novus Biologicals lysates for C17orf77
No data available for DME Specific Peptides for C17orf77 Gene
Domains & Families for C17orf77 Gene
No data available for Gene Families , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for C17orf77 Gene
Function for C17orf77 Gene
Phenotypes for C17orf77 Gene
- GenomeRNAi human phenotypes for C17orf77:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
-
OriGene CRISPR knockouts for C17orf77
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for C17orf77
- genomics-online: gRNA clones - Search for available C17ORF77 gRNA products
- Overview of 27 available C17ORF77 gene related products
- Applied Biological Materials (abm): CRISPR Clones for C17orf77 - Select products 50% OFF >
- * C17orf77 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * C17orf77 CRISPR applications: KO, Activation, Repression, and more - Browse All
-
Santa Cruz Biotechnology (SCBT) CRISPR for C17orf77
miRNA for C17orf77 Gene
- miRTarBase miRNAs that target C17orf77
-
- hsa-mir-148b-3p (MIRT019426)
- hsa-mir-3613-3p (MIRT644604)
- hsa-mir-5003-3p (MIRT644605)
- hsa-mir-548b-3p (MIRT644606)
- hsa-mir-3133 (MIRT644607)
- hsa-mir-5582-3p (MIRT644608)
- hsa-mir-548x-3p (MIRT644609)
- hsa-mir-548j-3p (MIRT644610)
- hsa-mir-548aq-3p (MIRT644611)
- hsa-mir-548am-3p (MIRT644612)
- hsa-mir-548aj-3p (MIRT644613)
- hsa-mir-548ah-3p (MIRT644614)
- hsa-mir-548ae-3p (MIRT644615)
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for C17orf77
- Browse OriGene Inhibitory RNA Products For C17orf77
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C17orf77
- genomics-online: shRNA clones - Search for available C17ORF77 shRNA products
- Overview of 27 available C17ORF77 gene related products
Clone Products
- Sino Biological Human cDNA Clone for C17orf77
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for C17orf77
- Applied Biological Materials (abm): Clones for C17orf77 - Select products 50% OFF >
- * C17orf77 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * C17orf77 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
Cell Line Products
-
Horizon Cell Lines for C17orf77
No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C17orf77 Gene
Localization for C17orf77 Gene
Subcellular locations from UniProtKB/Swiss-Prot for C17orf77 Gene
- Secreted.
| Compartment | Confidence |
|---|---|
| extracellular | 3 |
| cytosol | 1 |
| nucleus | 0 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for C17orf77 Gene
Transcripts for C17orf77 Gene
mRNA/cDNA for C17orf77 Gene
- (2) REFSEQ mRNAs :
- (2) Additional mRNA sequences :
- (5) Selected AceView cDNA sequences:
- (3) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000524389 641 bps (ENST00000524389.5)
- ENST00000392620 2525 bps (ENST00000392620.5)
- ENST00000328023 2470 bps (ENST00000328023.2)
- (3) RNACentral transcripts :
- (1) LNCipedia transcripts :
- (1) LncBook transcripts :
CRISPR Products
-
OriGene CRISPR knockouts for C17orf77
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for C17orf77
- genomics-online: gRNA clones - Search for available C17ORF77 gRNA products
- Overview of 27 available C17ORF77 gene related products
- Applied Biological Materials (abm): CRISPR Clones for C17orf77 - Select products 50% OFF >
- * C17orf77 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * C17orf77 CRISPR applications: KO, Activation, Repression, and more - Browse All
-
Santa Cruz Biotechnology (SCBT) CRISPR for C17orf77
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for C17orf77
- Browse OriGene Inhibitory RNA Products For C17orf77
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C17orf77
- genomics-online: shRNA clones - Search for available C17ORF77 shRNA products
- Overview of 27 available C17ORF77 gene related products
Clone Products
- Sino Biological Human cDNA Clone for C17orf77
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for C17orf77
- Applied Biological Materials (abm): Clones for C17orf77 - Select products 50% OFF >
- * C17orf77 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * C17orf77 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
Expression for C17orf77 Gene
mRNA differential expression in normal tissues according to GTEx for C17orf77 Gene
This gene is overexpressed in Breast - Mammary Tissue (x26.1), Colon - Transverse (x11.2), Small Intestine - Terminal Ileum (x10.4), and Cervix - Ectocervix (x5.2).
NURSA nuclear receptor signaling pathways regulating expression of C17orf77 Gene:
C17orf77SOURCE GeneReport for Unigene cluster for C17orf77 Gene:
Hs.350775Primer Products
-
OriGene qPCR primer pairs for C17orf77
- genomics-online: primer clones - Search for available C17ORF77 Primer products
- Overview of 27 available C17ORF77 gene related products
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C17orf77 Gene
Orthologs for C17orf77 Gene
This gene was present in the common ancestor of human and chimp.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | C17H17orf77 32 |
|
||
| C17orf77 33 |
|
OneToOne |
- Species where no ortholog for C17orf77 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- cow (Bos Taurus)
- dog (Canis familiaris)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- mouse (Mus musculus)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for C17orf77 Gene
No data available for Paralogs for C17orf77 Gene
Variants for C17orf77 Gene
| SNP ID | Clin | Chr 17 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000238531 | -- | 74,589,102(+) | C/G | intron_variant | |
| rs1000650393 | -- | 74,585,147(+) | G/A/T | intron_variant | |
| rs1000765123 | -- | 74,584,916(+) | T/A | genic_upstream_transcript_variant, splice_donor_variant, upstream_transcript_variant | |
| rs1001324339 | -- | 74,594,035(+) | A/G | 3_prime_UTR_variant | |
| rs1001522897 | -- | 74,583,591(+) | T/C | upstream_transcript_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv3282n100 | CNV | gain | 25217958 |
| dgv372n27 | CNV | gain | 19166990 |
| dgv5768n54 | CNV | gain | 21841781 |
| dgv5774n54 | CNV | gain | 21841781 |
| esv2751770 | CNV | gain | 17911159 |
| esv2761978 | CNV | gain | 21179565 |
| esv33995 | CNV | loss | 17666407 |
| esv3573820 | CNV | gain | 25503493 |
| esv3641230 | CNV | gain | 21293372 |
| esv3641244 | CNV | gain | 21293372 |
| nsv517569 | CNV | gain+loss | 19592680 |
Residual Variation Intolerance Score:
94.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
6.14;
75.65% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for C17orf77 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- C17orf77
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C17orf77 Gene
Disorders for C17orf77 Gene
Additional Disease Information for C17orf77
No disorders were found for C17orf77 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C17orf77 Gene
Publications for C17orf77 Gene
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 56
- DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PMID: 16625196) Zody MC … Nusbaum C (Nature 2006) 4 56
ExternalLinks
Products for C17orf77 Gene
- Custom Antibody ServicesOriGene Antibodies for C17orf77
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for C17orf77
- Search Origene for MassSpec and Protein Over-expression Lysates for C17orf77
- Origene Custom Protein Services for C17orf77
- Origene sirna, shrna, and RNAi products in human, mouse, rat for C17orf77
- Browse OriGene Inhibitory RNA Products For C17orf77
- OriGene qPCR primer pairs for C17orf77
- OriGene CRISPR knockouts for C17orf77
- OriGene ORF clones in human for C17orf77
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For C17orf77
- Sino Biological Human cDNA Clone for C17orf77
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals lysates for C17orf77
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- antibodies-online: Show 18 available C17ORF77 Antibodies ranked by validation data
- antibodies-online: Search results for available C17ORF77 related products ranked by validation data
- antibodies-online: Search results for available C17ORF77 related products ranked by validation data
- Horizon Cell Lines for C17orf77
- genomics-online: cdna clones - Search for available C17ORF77 CDNA products
- Overview of 27 available C17ORF77 gene related products
- orf clones - Search for available C17ORF77 ORF products
- Overview of 27 available C17ORF77 gene related products
- genomics-online: gRNA clones - Search for available C17ORF77 gRNA products
- Overview of 27 available C17ORF77 gene related products
- genomics-online: primer clones - Search for available C17ORF77 Primer products
- Overview of 27 available C17ORF77 gene related products
- genomics-online: shRNA clones - Search for available C17ORF77 shRNA products
- Overview of 27 available C17ORF77 gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for C17orf77
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for C17orf77
- Search GeneCopoeia for miRNA 3'UTR Target clone products for C17orf77
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C17orf77
Sources for C17orf77 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) CGAP SAGE
- (31) SOURCE
- (32) HomoloGene
- (33) PanEnsembl
- (34) euGenes
- (35) SGD
- (36) FlyBase
- (37) WormBase
- (38) Pseudogene
- (39) DGV
- (40) dbSNP
- (41) GenAtlas
- (42) HGMD
- (43) GAD
- (44) BGMUT
- (45) HuGE
- (46) Atlas
- (47) GenBank
- (48) H-invDB
- (49) HORDE
- (50) HUGE
- (51) IMGT
- (52) Leiden
- (53) miRBase
- (54) DME
- (55) OriGene
- (56) PubMed
- (57) R&D Systems
- (58) TGDB
- (59) Tocris
- (60) Abcam
- (61) Novus Biologicals
- (62) ProSpec
- (63) Sino Biological
- (64) GenScript
- (65) Qiagen
- (66) OCA
- (67) Proteopedia
- (68) MOPED
- (69) neXtProt
- (70) Reactome
- (71) GeneGo (Thomson Reuters)
- (72) DISEASES
- (73) SIMAP
- (74) GenomeRNAi
- (75) LifeMap
- (76) miRTarBase
- (77) MalaCards
- (78) Invitrogen
- (79) BitterDB
- (80) ESI-BIO
- (81) RefSeq
- (82) BioSystems
- (83) MaxQB
- (84) IUPHAR
- (85) BioGPS
- (86) Illumina
- (87) COMPARTMENTS
- (88) HOMER
- (89) PaxDb
- (90) ApexBio
- (91) Addgene
- (92) antibodies-online
- (93) CYP
- (94) NONCODE
- (95) TreeFam
- (96) PathCards
- (97) GeneReviews
- (98) GeneTex
- (99) Taconic Biosciences
- (100) GTEx
- (101) ProteomicsDB
- (102) SCBT
- (103) DGIdb
- (104) ClinicalTrials
- (105) RVIS
- (106) SIGNOR
- (107) diseasecard
- (108) NIH Rare Diseases
- (109) Orphanet
- (110) UMLS
- (111) GTR
- (112) Disease Ontology
- (113) Genetics Home Reference
- (114) MeSH
- (115) MedlinePlus
- (116) CDC
- (117) NINDS
- (118) NCBI Bookshelf
- (119) ClinVar
- (120) Gene Damage Index
- (121) HPO
- (122) UDN
- (123) VISTA
- (124) FANTOM5
- (125) ENCODE
- (126) ProSci
- (127) Horizon
- (128) NURSA
- (129) IID
- (130) VectorBuilder
- (131) SNPedia
- (132) BRCA Exchange
- (133) CIViC
- (134) ProteoGenix
- (135) dbSUPER
- (136) TISSUES
- (137) Gene ORGANizer
- (138) abm
- (139) Human Protein Atlas
- (140) GWAS Catalog
- (141) Monarch Initiative
- (142) DataMed
- (143) HumanCyc
- (144) genomics-online
- (145) UCNEbase
- (146) EPDnew
- (147) Applied Biosystems
- (148) GlyConnect
- (149) Aminode
- (150) GeneCopoeia
- (151) GPS-Prot
- (152) RNACentral
- (153) LncRNADisease
- (154) LOVD
- (155) miR2Disease
- (156) DiseaseEnhancer
- (157) Boster Bio
- (158) Biorbyt
- (159) Biocompare
- (160) Mastermind
- (161) CTD^2 Dashboard
- (162) CraniofacialAtlas
- (163) GeneImprint
- (164) Synthego
- (165) Bio Basic
- (166) ENA
- (167) GtRNAdb
- (168) LncBase
- (169) LncBook
- (170) LNCipedia
- (171) LncRNAdb
- (172) Modomics
- (173) PDBe
- (174) Rfam
- (175) SILVA
- (176) snOPY
- (177) SRPDB
- (178) GENCODE
- (179) TarBase
- (180) MyBioSource