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Aliases for C17orf112 Gene

Aliases for C17orf112 Gene

  • Chromosome 17 Open Reading Frame 112 2 3 5

External Ids for C17orf112 Gene

Previous GeneCards Identifiers for C17orf112 Gene

  • GC17P051065

Summaries for C17orf112 Gene

GeneCards Summary for C17orf112 Gene

C17orf112 (Chromosome 17 Open Reading Frame 112) is a Protein Coding gene.

Additional gene information for C17orf112 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C17orf112 Gene

Genomics for C17orf112 Gene

GeneHancer (GH) Regulatory Elements for C17orf112 Gene

Promoters and enhancers for C17orf112 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17I052982 Enhancer 0.2 FANTOM5 550.8 -1.6 -1646 0.3 C17orf112 LINC02089
GH17I053032 Enhancer 0.5 ENCODE 0.2 +49.0 48965 0.2 CTCF NFIC ZNF654 NFIA NFIB RAD21 GC17M053052 C17orf112
GH17I053033 Enhancer 0.4 ENCODE 0.2 +49.2 49225 0.2 CTCF NFIC GC17M053052 C17orf112
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around C17orf112 on UCSC Golden Path with GeneCards custom track

Genomic Locations for C17orf112 Gene

Genomic Locations for C17orf112 Gene
3,668 bases
Plus strand

Genomic View for C17orf112 Gene

Genes around C17orf112 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C17orf112 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C17orf112 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C17orf112 Gene

Proteins for C17orf112 Gene

  • Protein details for C17orf112 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C17orf112
    Protein Accession:

    Protein attributes for C17orf112 Gene

    114 amino acids
    Molecular mass:
    12668 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C17orf112 Gene

Post-translational modifications for C17orf112 Gene

No Post-translational modifications

Other Protein References for C17orf112 Gene

REFSEQ proteins:

No data available for DME Specific Peptides for C17orf112 Gene

Domains & Families for C17orf112 Gene

Protein Domains for C17orf112 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C17orf112: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C17orf112 Gene

Function for C17orf112 Gene

Phenotypes From GWAS Catalog for C17orf112 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C17orf112 Gene

Localization for C17orf112 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C17orf112 gene
Compartment Confidence
nucleus 2
cytosol 2
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for C17orf112 Gene

Pathways & Interactions for C17orf112 Gene

SuperPathways for C17orf112 Gene

No Data Available

Interacting Proteins for C17orf112 Gene

Gene Ontology (GO) - Biological Process for C17orf112 Gene


No data available for Pathways by source and SIGNOR curated interactions for C17orf112 Gene

Drugs & Compounds for C17orf112 Gene

No Compound Related Data Available

Transcripts for C17orf112 Gene

mRNA/cDNA for C17orf112 Gene

(2) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C17orf112 Gene

Chromosome 17 open reading frame 112:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C17orf112 Gene

No ASD Table

Relevant External Links for C17orf112 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C17orf112 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C17orf112 Gene

mRNA differential expression in normal tissues according to GTEx for C17orf112 Gene

This gene is overexpressed in Testis (x52.9).

NURSA nuclear receptor signaling pathways regulating expression of C17orf112 Gene:


SOURCE GeneReport for Unigene cluster for C17orf112 Gene:

genes like me logo Genes that share expression patterns with C17orf112: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C17orf112 Gene

Orthologs for C17orf112 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for C17orf112 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C17H17orf112 33
  • 98.54 (n)
C17orf112 34
  • 97 (a)
Species where no ortholog for C17orf112 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C17orf112 Gene

Gene Tree for C17orf112 (if available)
Gene Tree for C17orf112 (if available)

Paralogs for C17orf112 Gene

No data available for Paralogs for C17orf112 Gene

Variants for C17orf112 Gene

Sequence variations from dbSNP and Humsavar for C17orf112 Gene

SNP ID Clin Chr 17 pos Variation AA Info Type
rs1000249466 -- 52,985,385(+) C/T upstream_transcript_variant
rs1000495477 -- 52,988,124(+) C/T downstream_transcript_variant
rs1000528520 -- 52,986,988(+) T/A intron_variant
rs1001748027 -- 52,985,794(+) T/C intron_variant
rs1002080412 -- 52,987,134(+) T/C intron_variant

Structural Variations from Database of Genomic Variants (DGV) for C17orf112 Gene

Variant ID Type Subtype PubMed ID
dgv3264n100 CNV loss 25217958
dgv5691n54 CNV loss 21841781
dgv5692n54 CNV loss 21841781
dgv5693n54 CNV loss 21841781
esv2758695 CNV loss 17122850
esv3640792 CNV loss 21293372
nsv2091 CNV insertion 18451855
nsv457834 CNV loss 19166990
nsv523579 CNV loss 19592680
nsv528447 CNV loss 19592680
nsv828046 CNV loss 20364138
nsv9571 CNV loss 18304495

Variation tolerance for C17orf112 Gene

Gene Damage Index Score: 0.00; 0.05% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for C17orf112 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C17orf112 Gene

Disorders for C17orf112 Gene

Additional Disease Information for C17orf112

No disorders were found for C17orf112 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C17orf112 Gene

Publications for C17orf112 Gene

  1. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PMID: 16625196) Zody MC … Nusbaum C (Nature 2006) 4 58
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 58

Products for C17orf112 Gene

Sources for C17orf112 Gene

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