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Aliases for C17orf102 Gene

Aliases for C17orf102 Gene

  • Chromosome 17 Open Reading Frame 102 2 3 5

External Ids for C17orf102 Gene

Previous GeneCards Identifiers for C17orf102 Gene

  • GC17M029926
  • GC17M032901
  • GC17M029086

Summaries for C17orf102 Gene

GeneCards Summary for C17orf102 Gene

C17orf102 (Chromosome 17 Open Reading Frame 102) is a Protein Coding gene.

Additional gene information for C17orf102 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C17orf102 Gene

Genomics for C17orf102 Gene

GeneHancer (GH) Regulatory Elements for C17orf102 Gene

Promoters and enhancers for C17orf102 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17I034578 Promoter/Enhancer 1.6 EPDnew Ensembl ENCODE 550.8 -1.4 -1387 4.1 GLIS2 ZNF202 SP3 YY2 ZNF610 GLIS1 WT1 SP7 CTCF KLF1 TMEM132E C17orf102 LIG3 ZNF830 CCL7 GC17M034585
GH17I034412 Enhancer 1.5 FANTOM5 Ensembl ENCODE dbSUPER 10 +166.2 166200 1.8 PKNOX1 TAF9B NFRKB TCF12 CAVIN1 ELF1 ZNF592 ZNF148 MEF2D MAFF CCL2 CCL7 TMEM132E C17orf102 LIG3 ASIC2 CCL1 CCL8 GC17P034446 GC17M034364
GH17I034637 Enhancer 0.9 Ensembl ENCODE 11.8 -58.6 -58621 1.4 CTCF RB1 KLF17 ZIC2 RAD21 ARID2 SMC3 ZNF143 ZNF600 SMARCE1 C17orf102 TMEM132E GC17M034614 GC17M034729
GH17I034886 Enhancer 0.9 ENCODE 10.3 -307.6 -307568 0.2 HDAC1 PKNOX1 TCF12 ZNF766 GATA2 SIRT6 ATF7 CREM CEBPB NCOA1 C17orf102 TMEM132E GC17P034891 GC17P034858 LOC105371742
GH17I034885 Enhancer 0.9 ENCODE 10.3 -305.9 -305908 0.2 HDAC1 ATF1 SMAD1 ARNT ZBTB40 TCF12 ZNF766 GATA2 SIRT6 ETV6 C17orf102 TMEM132E GC17P034891 GC17P034858 LOC105371742
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around C17orf102 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the C17orf102 gene promoter:

Genomic Locations for C17orf102 Gene

Genomic Locations for C17orf102 Gene
chr17:34,574,123-34,579,369
(GRCh38/hg38)
Size:
5,247 bases
Orientation:
Minus strand
chr17:32,901,142-32,906,388
(GRCh37/hg19)

Genomic View for C17orf102 Gene

Genes around C17orf102 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C17orf102 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C17orf102 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C17orf102 Gene

Proteins for C17orf102 Gene

  • Protein details for C17orf102 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A2RUQ5-CQ102_HUMAN
    Recommended name:
    Uncharacterized protein C17orf102
    Protein Accession:
    A2RUQ5
    Secondary Accessions:
    • A5PKX0
    • Q6ZTB3

    Protein attributes for C17orf102 Gene

    Size:
    167 amino acids
    Molecular mass:
    17761 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C17orf102 Gene

Post-translational modifications for C17orf102 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C17orf102 Gene

REFSEQ proteins:

No data available for DME Specific Peptides for C17orf102 Gene

Domains & Families for C17orf102 Gene

Protein Domains for C17orf102 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C17orf102: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C17orf102 Gene

Function for C17orf102 Gene

Phenotypes From GWAS Catalog for C17orf102 Gene

genes like me logo Genes that share phenotypes with C17orf102: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C17orf102 Gene

Localization for C17orf102 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C17orf102 gene
Compartment Confidence
mitochondrion 2
extracellular 1
nucleus 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for C17orf102 Gene

Pathways & Interactions for C17orf102 Gene

SuperPathways for C17orf102 Gene

No Data Available

Interacting Proteins for C17orf102 Gene

Selected Interacting proteins: A2RUQ5-CQ102_HUMAN for C17orf102 Gene via IID

Gene Ontology (GO) - Biological Process for C17orf102 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C17orf102 Gene

Drugs & Compounds for C17orf102 Gene

No Compound Related Data Available

Transcripts for C17orf102 Gene

mRNA/cDNA for C17orf102 Gene

(1) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(2) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C17orf102 Gene

Chromosome 17 open reading frame 102:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for C17orf102 Gene

No ASD Table

Relevant External Links for C17orf102 Gene

GeneLoc Exon Structure for
C17orf102
ECgene alternative splicing isoforms for
C17orf102

Expression for C17orf102 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C17orf102 Gene

mRNA differential expression in normal tissues according to GTEx for C17orf102 Gene

This gene is overexpressed in Brain - Frontal Cortex (BA9) (x10.3), Brain - Cortex (x9.5), Brain - Anterior cingulate cortex (BA24) (x6.1), Brain - Hypothalamus (x5.0), Brain - Cerebellar Hemisphere (x4.3), and Brain - Cerebellum (x4.3).

Protein differential expression in normal tissues from HIPED for C17orf102 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C17orf102 Gene



Protein tissue co-expression partners for C17orf102 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of C17orf102 Gene:

C17orf102

SOURCE GeneReport for Unigene cluster for C17orf102 Gene:

Hs.514090
genes like me logo Genes that share expression patterns with C17orf102: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C17orf102 Gene

Orthologs for C17orf102 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for C17orf102 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C17H17orf102 33
  • 99.4 (n)
C17orf102 34
  • 98 (a)
OneToOne
Species where no ortholog for C17orf102 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C17orf102 Gene

ENSEMBL:
Gene Tree for C17orf102 (if available)
TreeFam:
Gene Tree for C17orf102 (if available)

Paralogs for C17orf102 Gene

No data available for Paralogs for C17orf102 Gene

Variants for C17orf102 Gene

Sequence variations from dbSNP and Humsavar for C17orf102 Gene

SNP ID Clin Chr 17 pos Variation AA Info Type
rs1000020337 -- 34,577,875(-) G/A intron_variant
rs1000167758 -- 34,578,267(-) G/C intron_variant
rs1000646060 -- 34,578,597(-) G/A intron_variant
rs1000908134 -- 34,576,760(-) A/T 3_prime_UTR_variant
rs1001694849 -- 34,576,351(-) A/T 3_prime_UTR_variant

Structural Variations from Database of Genomic Variants (DGV) for C17orf102 Gene

Variant ID Type Subtype PubMed ID
dgv3141n100 CNV gain 25217958
esv33292 CNV gain 17666407
esv3572553 CNV gain 25503493
esv3582611 CNV loss 25503493
nsv1055479 CNV gain 25217958
nsv519297 CNV gain 19592680
nsv574714 CNV gain 21841781

Variation tolerance for C17orf102 Gene

Residual Variation Intolerance Score: 80.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.82; 67.01% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for C17orf102 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C17orf102

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C17orf102 Gene

Disorders for C17orf102 Gene

Additional Disease Information for C17orf102

No disorders were found for C17orf102 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C17orf102 Gene

Publications for C17orf102 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  3. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  4. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin EL … Gygi SP (Cell 2015) 3 58
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58

Products for C17orf102 Gene

Sources for C17orf102 Gene

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