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Aliases for C17orf100 Gene

Aliases for C17orf100 Gene

  • Chromosome 17 Open Reading Frame 100 2 3 5
  • Uncharacterized Protein C17orf100 3
  • HCG1985469 3

External Ids for C17orf100 Gene

Previous GeneCards Identifiers for C17orf100 Gene

  • GC17P006497
  • GC17P006564

Summaries for C17orf100 Gene

GeneCards Summary for C17orf100 Gene

C17orf100 (Chromosome 17 Open Reading Frame 100) is a Protein Coding gene.

Additional gene information for C17orf100 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C17orf100 Gene

Genomics for C17orf100 Gene

GeneHancer (GH) Regulatory Elements for C17orf100 Gene

Promoters and enhancers for C17orf100 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17J006649 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 650.7 -0.2 -213 3.1 HDGF PKNOX1 CLOCK MLX ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 KIAA0753 C17orf100 MED31 PIR47256 DVL2 ENSG00000261996 SENP3 NEURL4 SNORD10 SNORA48
GH17J006699 Enhancer 0.9 ENCODE 10.8 +48.9 48850 1.8 FOXA2 MLX ARID4B ZNF48 ETS1 YY1 TCF12 SLC30A9 NFKBIZ RXRA XAF1 C17orf100 MED31 FBXO39 GC17M006685 SLC13A5
GH17J006913 Enhancer 0.9 Ensembl ENCODE 10.3 +262.4 262423 0.9 CTCF RB1 RAD21 CC2D1A POLR2A BRD9 ARID2 SMC3 ZNF143 CREM ALOX12 ALOX12-AS1 RNASEK RNASEK-C17orf49 MIR195 BCL6B SLC16A11 C17orf100 MED31 SLC13A5
GH17J006599 Enhancer 0.8 Ensembl ENCODE 11 -52.1 -52097 1.2 L3MBTL2 MAX MAFG MNT ZNF316 FOXK2 SMARCA4 IKZF1 NFE2 EMSY RNA5SP435 GC17M006601 KIAA0753 PITPNM3 TXNDC17 C17orf100 MED31 SLC13A5 GC17M006460
GH17J006843 Enhancer 0.6 ENCODE 10.2 +191.7 191739 0.2 CTCF ZNF654 RFX1 REST RAD21 SMC3 ZNF143 ZNF24 ALOX12 ALOX12-AS1 RNASEK RNASEK-C17orf49 SLC13A5 C17orf100 MED31 XAF1 SLC16A11 ALOX12P2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around C17orf100 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the C17orf100 gene promoter:

Genomic Locations for C17orf100 Gene

Genomic Locations for C17orf100 Gene
chr17:6,651,718-6,693,202
(GRCh38/hg38)
Size:
41,485 bases
Orientation:
Plus strand
chr17:6,554,971-6,556,791
(GRCh37/hg19)

Genomic View for C17orf100 Gene

Genes around C17orf100 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C17orf100 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C17orf100 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C17orf100 Gene

Proteins for C17orf100 Gene

  • Protein details for C17orf100 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A8MU93-CQ100_HUMAN
    Recommended name:
    Uncharacterized protein C17orf100
    Protein Accession:
    A8MU93
    Secondary Accessions:
    • D3DTM5

    Protein attributes for C17orf100 Gene

    Size:
    118 amino acids
    Molecular mass:
    13000 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C17orf100 Gene

Post-translational modifications for C17orf100 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C17orf100 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C17orf100 Gene

Domains & Families for C17orf100 Gene

Gene Families for C17orf100 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for C17orf100 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C17orf100: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C17orf100 Gene

Function for C17orf100 Gene

Phenotypes From GWAS Catalog for C17orf100 Gene

genes like me logo Genes that share phenotypes with C17orf100: view

Animal Model Products

miRNA for C17orf100 Gene

miRTarBase miRNAs that target C17orf100

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C17orf100 Gene

Localization for C17orf100 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C17orf100 gene
Compartment Confidence
nucleus 3

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytokinetic bridge (2)
  • Cytosol (2)
  • Nucleus (2)
See all subcellular structures

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C17orf100 Gene

Pathways & Interactions for C17orf100 Gene

SuperPathways for C17orf100 Gene

No Data Available

Interacting Proteins for C17orf100 Gene

Gene Ontology (GO) - Biological Process for C17orf100 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C17orf100 Gene

Drugs & Compounds for C17orf100 Gene

No Compound Related Data Available

Transcripts for C17orf100 Gene

mRNA/cDNA for C17orf100 Gene

(57) Selected AceView cDNA sequences:
(5) Additional mRNA sequences :
(1) REFSEQ mRNAs :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C17orf100 Gene

Chromosome 17 open reading frame 100:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for C17orf100 Gene

No ASD Table

Relevant External Links for C17orf100 Gene

GeneLoc Exon Structure for
C17orf100
ECgene alternative splicing isoforms for
C17orf100

Expression for C17orf100 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C17orf100 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C17orf100 Gene



NURSA nuclear receptor signaling pathways regulating expression of C17orf100 Gene:

C17orf100

SOURCE GeneReport for Unigene cluster for C17orf100 Gene:

Hs.262480
genes like me logo Genes that share expression patterns with C17orf100: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C17orf100 Gene

Orthologs for C17orf100 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C17orf100 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C17H17orf100 33
  • 98.87 (n)
cow
(Bos Taurus)
Mammalia C19H17orf100 33
  • 82.77 (n)
mouse
(Mus musculus)
Mammalia 4930563E22Rik 16 33
  • 79.58 (n)
rat
(Rattus norvegicus)
Mammalia LOC100912483 33
  • 77.4 (n)
Species where no ortholog for C17orf100 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C17orf100 Gene

ENSEMBL:
Gene Tree for C17orf100 (if available)
TreeFam:
Gene Tree for C17orf100 (if available)

Paralogs for C17orf100 Gene

No data available for Paralogs for C17orf100 Gene

Variants for C17orf100 Gene

Sequence variations from dbSNP and Humsavar for C17orf100 Gene

SNP ID Clin Chr 17 pos Variation AA Info Type
rs1000372565 -- 6,650,580(+) G/T upstream_transcript_variant
rs1000769204 -- 6,650,698(+) C/A upstream_transcript_variant
rs1002785708 -- 6,653,647(+) C/T downstream_transcript_variant
rs1004149025 -- 6,650,972(+) T/A upstream_transcript_variant
rs1005366114 -- 6,650,248(+) A/C upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for C17orf100 Gene

Variant ID Type Subtype PubMed ID
nsv574278 CNV gain 21841781

Variation tolerance for C17orf100 Gene

Gene Damage Index Score: 0.84; 17.63% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for C17orf100 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C17orf100

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C17orf100 Gene

Disorders for C17orf100 Gene

Additional Disease Information for C17orf100

No disorders were found for C17orf100 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C17orf100 Gene

Publications for C17orf100 Gene

  1. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PMID: 16625196) Zody MC … Nusbaum C (Nature 2006) 4 58
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 58
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58
  4. The sequence of the human genome. (PMID: 11181995) Venter JC … Zhu X (Science (New York, N.Y.) 2001) 3 58

Products for C17orf100 Gene

Sources for C17orf100 Gene

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