Aliases for C16orf95 Gene

Aliases for C16orf95 Gene

  • Chromosome 16 Open Reading Frame 95 2 3 5
  • Uncharacterized Protein C16orf95 3 4

External Ids for C16orf95 Gene

Previous GeneCards Identifiers for C16orf95 Gene

  • GC16M087340

Summaries for C16orf95 Gene

GeneCards Summary for C16orf95 Gene

C16orf95 (Chromosome 16 Open Reading Frame 95) is a Protein Coding gene. Diseases associated with C16orf95 include Vesicoureteral Reflux 1. An important paralog of this gene is ENSG00000131152.

Additional gene information for C16orf95 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for C16orf95 Gene

Genomics for C16orf95 Gene

GeneHancer (GH) Regulatory Elements for C16orf95 Gene

Promoters and enhancers for C16orf95 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around C16orf95 on UCSC Golden Path with GeneCards custom track

Genomic Locations for C16orf95 Gene

Genomic Locations for C16orf95 Gene
233,859 bases
Minus strand
233,859 bases
Minus strand

Genomic View for C16orf95 Gene

Genes around C16orf95 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C16orf95 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C16orf95 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C16orf95 Gene

Proteins for C16orf95 Gene

  • Protein details for C16orf95 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C16orf95
    Protein Accession:

    Protein attributes for C16orf95 Gene

    158 amino acids
    Molecular mass:
    16793 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C16orf95 Gene

Post-translational modifications for C16orf95 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C16orf95 Gene

No data available for DME Specific Peptides for C16orf95 Gene

Domains & Families for C16orf95 Gene

Gene Families for C16orf95 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for C16orf95 Gene

genes like me logo Genes that share domains with C16orf95: view

No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for C16orf95 Gene

Function for C16orf95 Gene

Phenotypes From GWAS Catalog for C16orf95 Gene

Animal Model Products

CRISPR Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C16orf95 Gene

Localization for C16orf95 Gene

Subcellular locations from the

Human Protein Atlas (HPA)
  • Endoplasmic reticulum (2)
See all subcellular structures

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for C16orf95 Gene

Pathways & Interactions for C16orf95 Gene

PathCards logo

SuperPathways for C16orf95 Gene

No Data Available

Interacting Proteins for C16orf95 Gene

Gene Ontology (GO) - Biological Process for C16orf95 Gene


No data available for Pathways by source and SIGNOR curated interactions for C16orf95 Gene

Drugs & Compounds for C16orf95 Gene

No Compound Related Data Available

Transcripts for C16orf95 Gene

mRNA/cDNA for C16orf95 Gene

(3) REFSEQ mRNAs :
(7) Additional mRNA sequences :
(7) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for C16orf95 Gene

No ASD Table

Relevant External Links for C16orf95 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C16orf95 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C16orf95 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C16orf95 Gene

This gene is overexpressed in Testis (x27.4).

Protein differential expression in normal tissues from HIPED for C16orf95 Gene

This gene is overexpressed in Lung (40.7), Fetal heart (17.2), and Urinary Bladder (11.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C16orf95 Gene

Protein tissue co-expression partners for C16orf95 Gene

NURSA nuclear receptor signaling pathways regulating expression of C16orf95 Gene:


SOURCE GeneReport for Unigene cluster for C16orf95 Gene:

genes like me logo Genes that share expression patterns with C16orf95: view

No data available for mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C16orf95 Gene

Orthologs for C16orf95 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C16orf95 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia LOC609239 32
  • 78.13 (n)
C16orf95 33
  • 53 (a)
(Bos Taurus)
Mammalia LOC100140115 32
  • 77.03 (n)
C16orf95 33
  • 48 (a)
(Mus musculus)
Mammalia 1700018B08Rik 17 33 32
  • 70.68 (n)
(Rattus norvegicus)
Mammalia LOC687560 32
  • 70.21 (n)
Species where no ortholog for C16orf95 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C16orf95 Gene

Gene Tree for C16orf95 (if available)
Gene Tree for C16orf95 (if available)

Paralogs for C16orf95 Gene

Paralogs for C16orf95 Gene

genes like me logo Genes that share paralogs with C16orf95: view

Variants for C16orf95 Gene

Sequence variations from dbSNP and Humsavar for C16orf95 Gene

SNP ID Clin Chr 16 pos Variation AA Info Type
rs1000081212 -- 87,304,642(-) C/A/G intron_variant
rs1000128223 -- 87,316,262(-) C/T intron_variant
rs1000266363 -- 87,312,596(-) G/A/T intron_variant
rs1000757766 -- 87,316,627(-) C/A intron_variant
rs1000978205 -- 87,319,152(-) C/G/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for C16orf95 Gene

Variant ID Type Subtype PubMed ID
dgv552e214 CNV loss 21293372
esv3582428 CNV loss 25503493
esv3639509 CNV gain 21293372
esv3639510 CNV gain 21293372
nsv1062525 CNV gain 25217958
nsv510694 CNV deletion 20534489
nsv833320 CNV gain 17160897

Variation tolerance for C16orf95 Gene

Gene Damage Index Score: 7.56; 82.44% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for C16orf95 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C16orf95 Gene

Disorders for C16orf95 Gene

MalaCards: The human disease database

(1) MalaCards diseases for C16orf95 Gene - From: DISEASES

Disorder Aliases PubMed IDs
vesicoureteral reflux 1
  • vur1
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for C16orf95

genes like me logo Genes that share disorders with C16orf95: view

No data available for UniProtKB/Swiss-Prot and Genatlas for C16orf95 Gene

Publications for C16orf95 Gene

  1. Identifying new associated pleiotropic SNPs with lipids by simultaneous test of multiple longitudinal traits: An Iranian family-based study. (PMID: 30658068) Hosseinzadeh N … Azizi F (Gene 2019) 2 3 56
  2. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein MY … Mann M (Cell 2015) 3 56
  3. Fine expression profiling of full-length transcripts using a size-unbiased cDNA library prepared with the vector-capping method. (PMID: 18487259) Oshikawa M … Kato S (DNA research : an international journal for rapid publication of reports on genes and genomes 2008) 3 56
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 56
  5. The LIFEdb database in 2006. (PMID: 16381901) Mehrle A … Wiemann S (Nucleic acids research 2006) 3 56

Products for C16orf95 Gene

Sources for C16orf95 Gene