Aliases for C16orf92 Gene

Aliases for C16orf92 Gene

  • Chromosome 16 Open Reading Frame 92 2 3 5
  • Uncharacterized Protein C16orf92 3 4
  • C16orf92 5
  • FLJ25404 2
  • FIMP 3

External Ids for C16orf92 Gene

Previous GeneCards Identifiers for C16orf92 Gene

  • GC16P029944
  • GC16P030034
  • GC16P027695
  • GC16P030035
  • GC16P030069

Summaries for C16orf92 Gene

GeneCards Summary for C16orf92 Gene

C16orf92 (Chromosome 16 Open Reading Frame 92) is a Protein Coding gene. Diseases associated with C16orf92 include Central Nervous System Germ Cell Tumor.

Additional gene information for C16orf92 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for C16orf92 Gene

Genomics for C16orf92 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for C16orf92 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around C16orf92 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for C16orf92

Top Transcription factor binding sites by QIAGEN in the C16orf92 gene promoter:
  • ARP-1
  • C/EBPalpha
  • CHOP-10
  • Egr-3
  • Evi-1
  • FOXO4
  • GR
  • GR-alpha
  • MAZR
  • RORalpha1

Genomic Locations for C16orf92 Gene

Genomic Locations for C16orf92 Gene
chr16:30,023,322-30,027,736
(GRCh38/hg38)
Size:
4,415 bases
Orientation:
Plus strand
chr16:30,034,655-30,039,057
(GRCh37/hg19)
Size:
4,403 bases
Orientation:
Plus strand

Genomic View for C16orf92 Gene

Genes around C16orf92 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C16orf92 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C16orf92 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C16orf92 Gene

Proteins for C16orf92 Gene

  • Protein details for C16orf92 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96LL3-CP092_HUMAN
    Recommended name:
    Uncharacterized protein C16orf92
    Protein Accession:
    Q96LL3
    Secondary Accessions:
    • Q494R8

    Protein attributes for C16orf92 Gene

    Size:
    132 amino acids
    Molecular mass:
    14383 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C16orf92 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C16orf92 Gene

Post-translational modifications for C16orf92 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C16orf92 Gene

No data available for DME Specific Peptides for C16orf92 Gene

Domains & Families for C16orf92 Gene

Gene Families for C16orf92 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Predicted membrane proteins

Protein Domains for C16orf92 Gene

InterPro:
ProtoNet:
genes like me logo Genes that share domains with C16orf92: view

No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for C16orf92 Gene

Function for C16orf92 Gene

Phenotypes From GWAS Catalog for C16orf92 Gene

Phenotypes for C16orf92 Gene

genes like me logo Genes that share phenotypes with C16orf92: view

Animal Models for C16orf92 Gene

MGI Knock Outs for C16orf92:

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C16orf92

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for C16orf92 Gene

Localization for C16orf92 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C16orf92 Gene

Membrane. Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C16orf92 gene
Compartment Confidence
plasma membrane 1
extracellular 1
cytosol 1
mitochondrion 0
peroxisome 0
nucleus 0

Gene Ontology (GO) - Cellular Components for C16orf92 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with C16orf92: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for C16orf92 Gene

Pathways & Interactions for C16orf92 Gene

PathCards logo

SuperPathways for C16orf92 Gene

No Data Available

Gene Ontology (GO) - Biological Process for C16orf92 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C16orf92 Gene

Drugs & Compounds for C16orf92 Gene

No Compound Related Data Available

Transcripts for C16orf92 Gene

mRNA/cDNA for C16orf92 Gene

3 REFSEQ mRNAs :
7 NCBI additional mRNA sequence :
4 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C16orf92

Alternative Splicing Database (ASD) splice patterns (SP) for C16orf92 Gene

ExUns: 1 ^ 2a · 2b ^ 3 ^ 4
SP1:
SP2: -

Relevant External Links for C16orf92 Gene

GeneLoc Exon Structure for
C16orf92

Expression for C16orf92 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for C16orf92 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C16orf92 Gene

This gene is overexpressed in Testis (x37.6) and Brain - Cerebellum (x4.6).

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for C16orf92

SOURCE GeneReport for Unigene cluster for C16orf92 Gene:

Hs.651588
genes like me logo Genes that share expression patterns with C16orf92: view

Primer Products

No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C16orf92 Gene

Orthologs for C16orf92 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C16orf92 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia C16H16orf92 30
  • 99.09 (n)
C16orf92 31
  • 99 (a)
OneToOne
Dog
(Canis familiaris)
Mammalia C6H16orf92 30
  • 78.48 (n)
C16orf92 31
  • 54 (a)
OneToOne
Cow
(Bos Taurus)
Mammalia C25H16orf92 30
  • 78.18 (n)
Rat
(Rattus norvegicus)
Mammalia RGD1563217 30
  • 75.15 (n)
Mouse
(Mus musculus)
Mammalia 4930451I11Rik 30 17 31
  • 73.39 (n)
OneToOne
Species where no ortholog for C16orf92 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for C16orf92 Gene

ENSEMBL:
Gene Tree for C16orf92 (if available)
TreeFam:
Gene Tree for C16orf92 (if available)

Paralogs for C16orf92 Gene

No data available for Paralogs for C16orf92 Gene

Variants for C16orf92 Gene

Additional dbSNP identifiers (rs#s) for C16orf92 Gene

Structural Variations from Database of Genomic Variants (DGV) for C16orf92 Gene

Variant ID Type Subtype PubMed ID
nsv1160384 CNV duplication 26073780

Variation tolerance for C16orf92 Gene

Residual Variation Intolerance Score: 68.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.54; 11.68% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for C16orf92 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C16orf92

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for C16orf92 Gene

Disorders for C16orf92 Gene

MalaCards: The human disease database

(1) MalaCards diseases for C16orf92 Gene - From: DISEASES

Disorder Aliases PubMed IDs
central nervous system germ cell tumor
  • central nervous system germ cell tumour
- elite association - COSMIC cancer census association via MalaCards
genes like me logo Genes that share disorders with C16orf92: view

No data available for UniProtKB/Swiss-Prot and Genatlas for C16orf92 Gene

Publications for C16orf92 Gene

  1. A reference map of the human binary protein interactome. (PMID: 32296183) Luck K … Calderwood MA (Nature 2020) 3
  2. Biological insights from 108 schizophrenia-associated genetic loci. (PMID: 25056061) Schizophrenia Working Group of the Psychiatric Genomics Consortium (Nature 2014) 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3

Products for C16orf92 Gene

Sources for C16orf92 Gene