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Aliases for C16orf87 Gene

Aliases for C16orf87 Gene

  • Chromosome 16 Open Reading Frame 87 2 3 5

External Ids for C16orf87 Gene

Previous GeneCards Identifiers for C16orf87 Gene

  • GC16M045394
  • GC16M032725

Summaries for C16orf87 Gene

GeneCards Summary for C16orf87 Gene

C16orf87 (Chromosome 16 Open Reading Frame 87) is a Protein Coding gene.

Additional gene information for C16orf87 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C16orf87 Gene

Genomics for C16orf87 Gene

GeneHancer (GH) Regulatory Elements for C16orf87 Gene

Promoters and enhancers for C16orf87 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16I046828 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 550.8 +0.9 943 3.4 PKNOX1 MLX ARNT ARID4B SIN3A DMAP1 YBX1 YY1 ZNF766 ZNF207 C16orf87 SHCBP1 GC16P046804
GH16I046832 Enhancer 0.7 ENCODE 550.8 -1.5 -1533 0.2 SOX13 SAP130 ARID4B ZNF384 CEBPG ZNF644 RARA NR2F6 CREM GATAD2A C16orf87 VPS35 ORC6 GPT2 CKBP1
GH16I046756 Enhancer 1.2 FANTOM5 ENCODE dbSUPER 6.5 +74.0 73999 1.7 CTCF TEAD4 ZSCAN4 ZIC2 CTBP1 POLR2A CBFA2T2 RCOR1 CHD2 EZH2 SHCBP1 C16orf87 ORC6 GC16M046768 MYLK3 GC16P046705
GH16I046727 Enhancer 0.4 dbSUPER 4.2 +100.3 100268 6.8 NFIA ZNF449 SHCBP1 MYLK3 VPS35 ORC6 ANKRD26P1 C16orf87 GC16P046705 GC16M046768
GH16I046826 Enhancer 0.5 Ensembl 0.8 +4.6 4601 0.4 SCRT1 SCRT2 JUNB CEBPB FOS SP7 C16orf87 GC16P046804
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around C16orf87 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the C16orf87 gene promoter:

Genomic Locations for C16orf87 Gene

Genomic Locations for C16orf87 Gene
chr16:46,796,607-46,831,411
(GRCh38/hg38)
Size:
34,805 bases
Orientation:
Minus strand
chr16:46,830,519-46,865,323
(GRCh37/hg19)

Genomic View for C16orf87 Gene

Genes around C16orf87 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C16orf87 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C16orf87 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C16orf87 Gene

Proteins for C16orf87 Gene

  • Protein details for C16orf87 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6PH81-CP087_HUMAN
    Recommended name:
    UPF0547 protein C16orf87
    Protein Accession:
    Q6PH81
    Secondary Accessions:
    • Q63HN9

    Protein attributes for C16orf87 Gene

    Size:
    154 amino acids
    Molecular mass:
    17799 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C16orf87 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C16orf87 Gene

Post-translational modifications for C16orf87 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C16orf87 Gene

No data available for DME Specific Peptides for C16orf87 Gene

Domains & Families for C16orf87 Gene

Gene Families for C16orf87 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for C16orf87 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for C16orf87 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6PH81

UniProtKB/Swiss-Prot:

CP087_HUMAN :
  • Belongs to the UPF0547 family.
Family:
  • Belongs to the UPF0547 family.
genes like me logo Genes that share domains with C16orf87: view

Function for C16orf87 Gene

Gene Ontology (GO) - Molecular Function for C16orf87 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 23752268
genes like me logo Genes that share ontologies with C16orf87: view

Phenotypes for C16orf87 Gene

genes like me logo Genes that share phenotypes with C16orf87: view

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C16orf87 Gene

Localization for C16orf87 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C16orf87 gene
Compartment Confidence
nucleus 4
plasma membrane 1
extracellular 1
mitochondrion 1
cytosol 1

Subcellular locations from the

Human Protein Atlas (HPA)

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C16orf87 Gene

Pathways & Interactions for C16orf87 Gene

SuperPathways for C16orf87 Gene

No Data Available

Gene Ontology (GO) - Biological Process for C16orf87 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C16orf87 Gene

Drugs & Compounds for C16orf87 Gene

No Compound Related Data Available

Transcripts for C16orf87 Gene

Unigene Clusters for C16orf87 Gene

Chromosome 16 open reading frame 87:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for C16orf87 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b
SP1: - -
SP2:
SP3: - - -
SP4: -

Relevant External Links for C16orf87 Gene

GeneLoc Exon Structure for
C16orf87
ECgene alternative splicing isoforms for
C16orf87

Expression for C16orf87 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C16orf87 Gene

Protein differential expression in normal tissues from HIPED for C16orf87 Gene

This gene is overexpressed in Blymphocyte (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for C16orf87 Gene



Protein tissue co-expression partners for C16orf87 Gene

NURSA nuclear receptor signaling pathways regulating expression of C16orf87 Gene:

C16orf87

SOURCE GeneReport for Unigene cluster for C16orf87 Gene:

Hs.406551
genes like me logo Genes that share expression patterns with C16orf87: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C16orf87 Gene

Orthologs for C16orf87 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C16orf87 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C16ORF87 34
  • 100 (a)
OneToOne
C16H16orf87 33
  • 99.5 (n)
dog
(Canis familiaris)
Mammalia C16orf87 34
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C18H16orf87 33 34
  • 97.84 (n)
rat
(Rattus norvegicus)
Mammalia RGD1308706 33
  • 95.45 (n)
mouse
(Mus musculus)
Mammalia 4921524J17Rik 33 16 34
  • 95.02 (n)
oppossum
(Monodelphis domestica)
Mammalia C16orf87 34
  • 95 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C16orf87 34
  • 87 (a)
OneToOne
chicken
(Gallus gallus)
Aves C11H16ORF87 33 34
  • 86.58 (n)
tropical clawed frog
(Silurana tropicalis)
Amphibia c16orf87 33
  • 74.54 (n)
zebrafish
(Danio rerio)
Actinopterygii C7H16orf87 34
  • 77 (a)
OneToOne
zgc:92818 33
  • 71.27 (n)
Dr.14841 33
Species where no ortholog for C16orf87 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C16orf87 Gene

ENSEMBL:
Gene Tree for C16orf87 (if available)
TreeFam:
Gene Tree for C16orf87 (if available)

Paralogs for C16orf87 Gene

No data available for Paralogs for C16orf87 Gene

Variants for C16orf87 Gene

Sequence variations from dbSNP and Humsavar for C16orf87 Gene

SNP ID Clin Chr 16 pos Variation AA Info Type
rs1000035424 -- 46,814,961(-) T/C intron_variant
rs1000366018 -- 46,828,362(-) AAAAAAAA/AAAAAAAAA intron_variant
rs1000401246 -- 46,820,344(-) T/C intron_variant
rs1000432264 -- 46,820,673(-) A/G intron_variant
rs1000609758 -- 46,813,727(-) A/G intron_variant

Structural Variations from Database of Genomic Variants (DGV) for C16orf87 Gene

Variant ID Type Subtype PubMed ID
esv3571142 CNV gain 25503493
esv3638541 CNV gain 21293372
nsv1066115 CNV gain 25217958
nsv526656 CNV gain 19592680

Variation tolerance for C16orf87 Gene

Residual Variation Intolerance Score: 39.8% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for C16orf87 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C16orf87

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C16orf87 Gene

Disorders for C16orf87 Gene

Additional Disease Information for C16orf87

No disorders were found for C16orf87 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C16orf87 Gene

Publications for C16orf87 Gene

  1. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin EL … Gygi SP (Cell 2015) 3 58
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3 58
  4. The functional interactome landscape of the human histone deacetylase family. (PMID: 23752268) Joshi P … Cristea IM (Molecular systems biology 2013) 3 58
  5. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A … Hentze MW (Cell 2012) 3 58

Products for C16orf87 Gene

Sources for C16orf87 Gene

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