Aliases for C16orf86 Gene

Aliases for C16orf86 Gene

  • Chromosome 16 Open Reading Frame 86 2 3 5
  • Uncharacterized Protein C16orf86 3 4

External Ids for C16orf86 Gene

Previous GeneCards Identifiers for C16orf86 Gene

  • GC16P066259
  • GC16P067701
  • GC16P053573

Summaries for C16orf86 Gene

GeneCards Summary for C16orf86 Gene

C16orf86 (Chromosome 16 Open Reading Frame 86) is a Protein Coding gene.

Additional gene information for C16orf86 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for C16orf86 Gene

Genomics for C16orf86 Gene

GeneHancer (GH) Regulatory Elements for C16orf86 Gene

Promoters and enhancers for C16orf86 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around C16orf86 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for C16orf86

Top Transcription factor binding sites by QIAGEN in the C16orf86 gene promoter:
  • AML1a
  • GATA-1
  • Nkx2-5
  • Pax-5

Genomic Locations for C16orf86 Gene

Genomic Locations for C16orf86 Gene
1,953 bases
Plus strand
1,945 bases
Plus strand

Genomic View for C16orf86 Gene

Genes around C16orf86 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C16orf86 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C16orf86 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C16orf86 Gene

Proteins for C16orf86 Gene

  • Protein details for C16orf86 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C16orf86
    Protein Accession:
    Secondary Accessions:
    • B5MCW6

    Protein attributes for C16orf86 Gene

    317 amino acids
    Molecular mass:
    33511 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAC85694.1; Type=Miscellaneous discrepancy; Note=Intron retention.; Evidence={ECO:0000305};

neXtProt entry for C16orf86 Gene

Post-translational modifications for C16orf86 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C16orf86 Gene

No data available for DME Specific Peptides for C16orf86 Gene

Domains & Families for C16orf86 Gene

Gene Families for C16orf86 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for C16orf86 Gene

genes like me logo Genes that share domains with C16orf86: view

No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for C16orf86 Gene

Function for C16orf86 Gene

Phenotypes From GWAS Catalog for C16orf86 Gene

genes like me logo Genes that share phenotypes with C16orf86: view

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C16orf86 Gene

Localization for C16orf86 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C16orf86 gene
Compartment Confidence
nucleus 2
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for C16orf86 Gene

Pathways & Interactions for C16orf86 Gene

PathCards logo

SuperPathways for C16orf86 Gene

No Data Available

Interacting Proteins for C16orf86 Gene


Gene Ontology (GO) - Biological Process for C16orf86 Gene


No data available for Pathways by source and SIGNOR curated interactions for C16orf86 Gene

Drugs & Compounds for C16orf86 Gene

No Compound Related Data Available

Transcripts for C16orf86 Gene

mRNA/cDNA for C16orf86 Gene

8 NCBI additional mRNA sequence :
6 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for C16orf86 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4
SP2: -
SP3: -
SP4: - -

Relevant External Links for C16orf86 Gene

GeneLoc Exon Structure for

Expression for C16orf86 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for C16orf86 Gene

mRNA differential expression in normal tissues according to GTEx for C16orf86 Gene

This gene is overexpressed in Testis (x6.7), Brain - Cerebellum (x5.3), and Brain - Cerebellar Hemisphere (x4.2).

Protein differential expression in normal tissues from HIPED for C16orf86 Gene

This gene is overexpressed in Testis (58.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C16orf86 Gene

Protein tissue co-expression partners for C16orf86 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for C16orf86

SOURCE GeneReport for Unigene cluster for C16orf86 Gene:

genes like me logo Genes that share expression patterns with C16orf86: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C16orf86 Gene

Orthologs for C16orf86 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C16orf86 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C16H16orf86 30
  • 98.84 (n)
C16orf86 31
  • 98 (a)
(Canis familiaris)
Mammalia C5H16orf86 30
  • 81.81 (n)
C16orf86 31
  • 71 (a)
(Bos Taurus)
Mammalia C18H16orf86 30
  • 79.01 (n)
C16orf86 31
  • 71 (a)
(Rattus norvegicus)
Mammalia RGD1561415 30
  • 76.08 (n)
(Mus musculus)
Mammalia 4933405L10Rik 17 31 30
  • 74.12 (n)
Species where no ortholog for C16orf86 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C16orf86 Gene

Gene Tree for C16orf86 (if available)
Gene Tree for C16orf86 (if available)

Paralogs for C16orf86 Gene

No data available for Paralogs for C16orf86 Gene

Variants for C16orf86 Gene

Additional dbSNP identifiers (rs#s) for C16orf86 Gene

Structural Variations from Database of Genomic Variants (DGV) for C16orf86 Gene

Variant ID Type Subtype PubMed ID
nsv522852 CNV gain 19592680
nsv524363 CNV loss 19592680
nsv952046 CNV deletion 24416366

Variation tolerance for C16orf86 Gene

Residual Variation Intolerance Score: 59.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.12; 22.69% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for C16orf86 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for C16orf86 Gene

Disorders for C16orf86 Gene

Additional Disease Information for C16orf86

No disorders were found for C16orf86 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C16orf86 Gene

Publications for C16orf86 Gene

  1. Biological insights from 108 schizophrenia-associated genetic loci. (PMID: 25056061) Schizophrenia Working Group of the Psychiatric Genomics Consortium (Nature 2014) 3 54
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 4 54
  3. The sequence and analysis of duplication-rich human chromosome 16. (PMID: 15616553) Martin J … Pennacchio LA (Nature 2004) 4 54
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 54

Products for C16orf86 Gene

Sources for C16orf86 Gene