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Aliases for C16orf54 Gene
Aliases for C16orf54 Gene
External Ids for C16orf54 Gene
- HGNC: 26649
- Entrez Gene: 283897
- Ensembl: ENSG00000185905
- UniProtKB: Q6UWD8
Previous GeneCards Identifiers for C16orf54 Gene
- GC16M029662
- GC16M029663
- GC16M029753
- GC16M027414
Summaries for C16orf54 Gene
GeneCards Summary for C16orf54 Gene
C16orf54 (Chromosome 16 Open Reading Frame 54) is a Protein Coding gene. Diseases associated with C16orf54 include Central Nervous System Germ Cell Tumor.
Additional gene information for C16orf54 Gene
- HGNC(26649)
- Entrez Gene(283897)
- Ensembl(ENSG00000185905)
- UniProtKB(Q6UWD8)
- Open Targets Platform(ENSG00000185905)
- Search for C16orf54 at DataMed
- Search for C16orf54 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for C16orf54 Gene
Genomics for C16orf54 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for C16orf54 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around C16orf54 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for C16orf54
- Top Transcription factor binding sites by QIAGEN in the C16orf54 gene promoter:
-
- AML1a
- E2F
- E2F-1
- E2F-2
- E2F-3a
- E2F-4
- E2F-5
- E47
- LCR-F1
- Tal-1
Genomic Locations for C16orf54 Gene
Genomic Locations for C16orf54 Gene
- chr16:29,742,463-29,745,990
- (GRCh38/hg38)
- Size:
- 3,528 bases
- Orientation:
- Minus strand
- chr16:29,753,784-29,757,340
- (GRCh37/hg19)
- Size:
- 3,557 bases
- Orientation:
- Minus strand
Genomic View for C16orf54 Gene
Genes around C16orf54 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 16p11.2 by HGNC
- 16p11.2 by Entrez Gene
- 16p11.2 by Ensembl
C16orf54 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for C16orf54 Gene
Proteins for C16orf54 Gene
-
Protein details for C16orf54 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q6UWD8-CP054_HUMAN
- Recommended name:
- Transmembrane protein C16orf54
- Protein Accession:
- Q6UWD8
- A6NJR6
- Q8NAB0
Protein attributes for C16orf54 Gene
- Size:
- 224 amino acids
- Molecular mass:
- 24360 Da
- Quaternary structure:
- No Data Available
Protein Expression for C16orf54 Gene
Post-translational modifications for C16orf54 Gene
Other Protein References for C16orf54 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for C16orf54
- Invitrogen Antibodies for C16orf54 (AFLGC-C16orf54)
- antibodies-online: Show 9 available C16ORF54 Antibodies ranked by validation data
-
Biorbyt antibodies for C16orf54
Protein Products
-
OriGene Purified Proteins for C16orf54
- Search Origene for MassSpec and Protein Over-expression Lysates for C16orf54
- Origene Custom Protein Services for C16orf54
- Novus Biologicals proteins for C16orf54
No data available for DME Specific Peptides for C16orf54 Gene
Domains & Families for C16orf54 Gene
Gene Families for C16orf54 Gene
- Human Protein Atlas (HPA):
-
- Predicted membrane proteins
Suggested Antigen Peptide Sequences for C16orf54 Gene
- GenScript: Design optimal peptide antigens:
-
- Transmembrane protein C16orf54 (CP054_HUMAN)
No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for C16orf54 Gene
Function for C16orf54 Gene
Phenotypes From GWAS Catalog for C16orf54 Gene
Phenotypes for C16orf54 Gene
- GenomeRNAi human phenotypes for C16orf54:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for C16orf54 - Select products 50% OFF >
- * C16orf54 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for C16orf54
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for C16orf54
-
Santa Cruz Biotechnology (SCBT) CRISPR for C16orf54
miRNA for C16orf54 Gene
- miRTarBase miRNAs that target C16orf54
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for C16orf54
- Browse OriGene Inhibitory RNA Products For C16orf54
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C16orf54
Clone Products
- Applied Biological Materials (abm): Clones for C16orf54 - Select products 50% OFF >
- * C16orf54 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for C16orf54
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for C16orf54
Cell Line Products
-
Horizon Cell Lines for C16orf54
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C16orf54 Gene
Localization for C16orf54 Gene
Subcellular locations from UniProtKB/Swiss-Prot for C16orf54 Gene
- Membrane. Single-pass membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 2 |
| mitochondrion | 1 |
| peroxisome | 1 |
| cytosol | 1 |
| nucleus | 0 |
| golgi apparatus | 0 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for C16orf54 Gene
Pathways & Interactions for C16orf54 Gene
Interacting Proteins for C16orf54 Gene
Selected Interacting proteins:
Q6UWD8-CP054_HUMAN
ENSP00000327506
for C16orf54 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for C16orf54
No data available for Pathways by source and SIGNOR curated interactions for C16orf54 Gene
Transcripts for C16orf54 Gene
mRNA/cDNA for C16orf54 Gene
- 1 REFSEQ mRNAs :
- 6 NCBI additional mRNA sequence :
- 1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000329410 2569 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for C16orf54 - Select products 50% OFF >
- * C16orf54 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for C16orf54
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for C16orf54
-
Santa Cruz Biotechnology (SCBT) CRISPR for C16orf54
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for C16orf54
- Browse OriGene Inhibitory RNA Products For C16orf54
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C16orf54
Clone Products
- Applied Biological Materials (abm): Clones for C16orf54 - Select products 50% OFF >
- * C16orf54 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for C16orf54
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for C16orf54
Relevant External Links for C16orf54 Gene
- GeneLoc Exon Structure for
- C16orf54
Expression for C16orf54 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Pancreas (Endocrine System)
- Endocrine Progenitor Cells Dorsal Pancreatic Bud
- Endocrine Progenitor Cells Ventral Pancreatic Bud
-
Epithelial Cells
- Endocrine Progenitor Cells Dorsal Pancreatic Bud
- Endocrine Progenitor Cells Ventral Pancreatic Bud
-
Blood (Hematopoietic System)
- Granulocytes Peripheral Blood
-
Extraembryonic Mesoderm (Extraembryonic Tissues)
- Extraembryonic Angioblasts Extraembryonic Capillary Plexus
-
Endothelium (Cardiovascular System)
- Extraembryonic Angioblasts Extraembryonic Capillary Plexus
mRNA differential expression in normal tissues according to GTEx for C16orf54 Gene
This gene is overexpressed in Whole Blood (x38.9).
This gene is overexpressed in CD8 Tcells (17.3), Plasma (11.5), Peripheral blood mononuclear cells (10.9), Monocytes (8.5), NK cells (7.6), and Platelet (7.4).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C16orf54 Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for C16orf54
SOURCE GeneReport for Unigene cluster for C16orf54 Gene:
Hs.331095Evidence on tissue expression from TISSUES for C16orf54 Gene
- Spleen(4.2)
Primer Products
-
OriGene qPCR primer pairs for C16orf54
Gene Expression Assay Products
No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for C16orf54 Gene
Orthologs for C16orf54 Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | C16H16orf54 30 |
|
||
| C16orf54 31 |
|
OneToOne | |||
| Cow (Bos Taurus) |
Mammalia | C25H16orf54 30 |
|
||
| C16orf54 31 |
|
OneToOne | |||
| Dog (Canis familiaris) |
Mammalia | C6H16orf54 30 |
|
||
| C16orf54 31 |
|
OneToOne | |||
| Mouse (Mus musculus) |
Mammalia | AI467606 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | LOC308990 30 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | C16orf54 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
OneToMany | |
| -- 31 |
|
OneToMany |
- Species where no ortholog for C16orf54 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
- Zebrafish (Danio rerio)
Paralogs for C16orf54 Gene
No data available for Paralogs for C16orf54 Gene
Variants for C16orf54 Gene
Gene Damage Index Score:
2.08;
38.11% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for C16orf54 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- C16orf54
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for C16orf54 Gene
Disorders for C16orf54 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| central nervous system germ cell tumor |
|
|
Search C16orf54 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for C16orf54
No data available for UniProtKB/Swiss-Prot and Genatlas for C16orf54 Gene
Publications for C16orf54 Gene
- The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark HF … Gray A (Genome research 2003) 2 3 4
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
- A reference map of the human binary protein interactome. (PMID: 32296183) Luck K … Calderwood MA (Nature 2020) 3
- Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3
ExternalLinks
Products for C16orf54 Gene
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for C16orf54
- Search Origene for MassSpec and Protein Over-expression Lysates for C16orf54
- Origene Custom Protein Services for C16orf54
- Origene shrna, sirna, and RNAi products in human, mouse, rat for C16orf54
- Browse OriGene Inhibitory RNA Products For C16orf54
- OriGene qPCR primer pairs for C16orf54
- OriGene CRISPR knockouts for C16orf54
- OriGene ORF clones in human for C16orf54
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For C16orf54
- Sino Biological Human cDNA Clone for C16orf54
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for C16orf54
- Novus Biologicals proteins for C16orf54
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Invitrogen Antibodies for C16orf54 (AFLGC-C16orf54)
- VectorBuilder Custom and pre-made DNA vectors for C16orf54 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for C16orf54 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for C16orf54 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for C16orf54 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for C16orf54
- antibodies-online: Show 9 available C16ORF54 Antibodies ranked by validation data
- antibodies-online: Search results for available C16ORF54 related products ranked by validation data
- antibodies-online: Search results for available C16ORF54 related products ranked by validation data
- Horizon Cell Lines for C16orf54
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for C16orf54
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for C16orf54
- Search GeneCopoeia for miRNA 3'UTR Target clone products for C16orf54
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C16orf54
- Biorbyt antibodies for C16orf54
Sources for C16orf54 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB