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Aliases for C12orf77 Gene
Aliases for C12orf77 Gene
External Ids for C12orf77 Gene
- HGNC: 27282
- Entrez Gene: 196415
- Ensembl: ENSG00000226397
- UniProtKB: C9JDV5
Previous GeneCards Identifiers for C12orf77 Gene
- GC12M025038
- GC12M025146
- GC12M024916
Summaries for C12orf77 Gene
GeneCards Summary for C12orf77 Gene
C12orf77 (Chromosome 12 Open Reading Frame 77) is a Protein Coding gene.
Additional gene information for C12orf77 Gene
- HGNC(27282)
- Entrez Gene(196415)
- Ensembl(ENSG00000226397)
- UniProtKB(C9JDV5)
- Open Targets Platform(ENSG00000226397)
- Search for C12orf77 at DataMed
- Search for C12orf77 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for C12orf77 Gene
Genomics for C12orf77 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for C12orf77 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around C12orf77 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for C12orf77
Genomic Locations for C12orf77 Gene
Genomic Locations for C12orf77 Gene
- chr12:24,993,424-25,006,403
- (GRCh38/hg38)
- Size:
- 12,980 bases
- Orientation:
- Minus strand
- chr12:25,146,358-25,150,453
- (GRCh37/hg19)
- Size:
- 4,096 bases
- Orientation:
- Minus strand
Genomic View for C12orf77 Gene
Genes around C12orf77 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 12p12.1 by HGNC
- 12p12.1 by Entrez Gene
- 12p12.1 by Ensembl
C12orf77 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for C12orf77 Gene
Proteins for C12orf77 Gene
-
Protein details for C12orf77 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- C9JDV5-CL097_HUMAN
- Recommended name:
- Putative uncharacterized protein C12orf77
- Protein Accession:
- C9JDV5
Protein attributes for C12orf77 Gene
- Size:
- 145 amino acids
- Molecular mass:
- 16178 Da
- Quaternary structure:
- No Data Available
Post-translational modifications for C12orf77 Gene
Other Protein References for C12orf77 Gene
- REFSEQ proteins:
Antibody Products
- Creative Diagnostics Anti-C12orf77 polyclonal antibody
Protein Products
-
OriGene Purified Proteins for C12orf77
- Search Origene for MassSpec and Protein Over-expression Lysates for C12orf77
- Origene Custom Protein Services for C12orf77
No data available for DME Specific Peptides for C12orf77 Gene
Domains & Families for C12orf77 Gene
No data available for Gene Families , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for C12orf77 Gene
Function for C12orf77 Gene
Phenotypes From GWAS Catalog for C12orf77 Gene
Phenotypes for C12orf77 Gene
- GenomeRNAi human phenotypes for C12orf77:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for C12orf77 - Select products 50% OFF >
- * C12orf77 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for C12orf77
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for C12orf77
-
Santa Cruz Biotechnology (SCBT) CRISPR for C12orf77
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for C12orf77
- Browse OriGene Inhibitory RNA Products For C12orf77
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C12orf77
Clone Products
- Applied Biological Materials (abm): Clones for C12orf77 - Select products 50% OFF >
- * C12orf77 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene ORF clones in human for C12orf77
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for C12orf77
Cell Line Products
-
Horizon Cell Lines for C12orf77
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C12orf77 Gene
Localization for C12orf77 Gene
| Compartment | Confidence |
|---|---|
| plasma membrane | 1 |
| extracellular | 1 |
| nucleus | 1 |
| cytosol | 1 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for C12orf77 Gene
Transcripts for C12orf77 Gene
mRNA/cDNA for C12orf77 Gene
- 1 REFSEQ mRNAs :
- 3 NCBI additional mRNA sequence :
- 3 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000623395 1516 nts (view in UCSC)
- ENST00000549262 1443 nts (view in UCSC)
- ENST00000434912 675 nts (view in UCSC)
- 5 RNACentral transcripts :
- 5 LNCipedia transcripts :
- 1 NONCODE transcripts :
- 1 LncBook transcripts :
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for C12orf77 - Select products 50% OFF >
- * C12orf77 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for C12orf77
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for C12orf77
-
Santa Cruz Biotechnology (SCBT) CRISPR for C12orf77
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for C12orf77
- Browse OriGene Inhibitory RNA Products For C12orf77
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C12orf77
Clone Products
- Applied Biological Materials (abm): Clones for C12orf77 - Select products 50% OFF >
- * C12orf77 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene ORF clones in human for C12orf77
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for C12orf77
Relevant External Links for C12orf77 Gene
- GeneLoc Exon Structure for
- C12orf77
Expression for C12orf77 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for C12orf77
SOURCE GeneReport for Unigene cluster for C12orf77 Gene:
Hs.434453Primer Products
-
OriGene qPCR primer pairs for C12orf77
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C12orf77 Gene
Orthologs for C12orf77 Gene
This gene was present in the common ancestor of human and chimp.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | C12H12orf77 30 |
|
||
| C12orf77 31 |
|
OneToOne |
- Species where no ortholog for C12orf77 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- Cow (Bos Taurus)
- Dog (Canis familiaris)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Mouse (Mus musculus)
- Oppossum (Monodelphis domestica)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rat (Rattus norvegicus)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
- Zebrafish (Danio rerio)
Paralogs for C12orf77 Gene
No data available for Paralogs for C12orf77 Gene
Variants for C12orf77 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for C12orf77 Gene
| SNP ID | Clinical significance and condition | Chr 12 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs864161 | - | p.Leu131Phe |
Residual Variation Intolerance Score:
72.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.11;
38.54% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for C12orf77 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- C12orf77
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C12orf77 Gene
Disorders for C12orf77 Gene
Additional Disease Information for C12orf77
- Genetic Association Database
- (GAD)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No disorders were found for C12orf77 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C12orf77 Gene
Publications for C12orf77 Gene
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3
- Genome-wide association with bone mass and geometry in the Framingham Heart Study. (PMID: 17903296) Kiel DP … Karasik D (BMC medical genetics 2007) 41
- The finished DNA sequence of human chromosome 12. (PMID: 16541075) Scherer SE … Baylor College of Medicine Human Genome Sequencing Center Sequence Production Team (Nature 2006) 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4
ExternalLinks
Products for C12orf77 Gene
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for C12orf77
- Search Origene for MassSpec and Protein Over-expression Lysates for C12orf77
- Origene Custom Protein Services for C12orf77
- Origene shrna, sirna, and RNAi products in human, mouse, rat for C12orf77
- Browse OriGene Inhibitory RNA Products For C12orf77
- OriGene qPCR primer pairs for C12orf77
- OriGene CRISPR knockouts for C12orf77
- OriGene ORF clones in human for C12orf77
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For C12orf77
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- VectorBuilder Custom and pre-made DNA vectors for C12orf77 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for C12orf77 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for C12orf77 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for C12orf77 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for C12orf77
- Horizon Cell Lines for C12orf77
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for C12orf77
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for C12orf77
- Search GeneCopoeia for miRNA 3'UTR Target clone products for C12orf77
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C12orf77
Sources for C12orf77 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB