Free for academic non-profit institutions. Other users need a Commercial license
Aliases for C12orf71 Gene
Aliases for C12orf71 Gene
External Ids for C12orf71 Gene
- HGNC: 34452
- Entrez Gene: 728858
- Ensembl: ENSG00000214700
- UniProtKB: A8MTZ7
Previous GeneCards Identifiers for C12orf71 Gene
- GC12M027128
- GC12M027233
- GC12M027003
Summaries for C12orf71 Gene
GeneCards Summary for C12orf71 Gene
C12orf71 (Chromosome 12 Open Reading Frame 71) is a Protein Coding gene.
Additional gene information for C12orf71 Gene
- HGNC(34452)
- Entrez Gene(728858)
- Ensembl(ENSG00000214700)
- UniProtKB(A8MTZ7)
- Open Targets Platform(ENSG00000214700)
- Search for C12orf71 at DataMed
- Search for C12orf71 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for C12orf71 Gene
Genomics for C12orf71 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for C12orf71 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around C12orf71 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for C12orf71
- Top Transcription factor binding sites by QIAGEN in the C12orf71 gene promoter:
-
- FOXF2
- FOXO3
- FOXO3a
- FOXO3b
- FOXO4
- GATA-1
- GATA-2
- GATA-3
- LCR-F1
Genomic Locations for C12orf71 Gene
Genomic Locations for C12orf71 Gene
- chr12:27,081,057-27,084,548
- (GRCh38/hg38)
- Size:
- 3,492 bases
- Orientation:
- Minus strand
- chr12:27,233,990-27,235,455
- (GRCh37/hg19)
- Size:
- 1,466 bases
- Orientation:
- Minus strand
Genomic View for C12orf71 Gene
Genes around C12orf71 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 12p11.23 by HGNC
- 12p11.23 by Entrez Gene
- 12p11.23 by Ensembl
C12orf71 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for C12orf71 Gene
Proteins for C12orf71 Gene
-
Protein details for C12orf71 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- A8MTZ7-CL071_HUMAN
- Recommended name:
- Uncharacterized protein C12orf71
- Protein Accession:
- A8MTZ7
Protein attributes for C12orf71 Gene
- Size:
- 269 amino acids
- Molecular mass:
- 30355 Da
- Quaternary structure:
- No Data Available
Protein Expression for C12orf71 Gene
Post-translational modifications for C12orf71 Gene
Other Protein References for C12orf71 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for C12orf71
- Invitrogen Antibodies for C12orf71 (AFLGC-C12orf71)
Protein Products
-
OriGene Purified Proteins for C12orf71
- Search Origene for MassSpec and Protein Over-expression Lysates for C12orf71
- Origene Custom Protein Services for C12orf71
- Novus Biologicals proteins for C12orf71
No data available for DME Specific Peptides for C12orf71 Gene
Domains & Families for C12orf71 Gene
Gene Families for C12orf71 Gene
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for C12orf71 Gene
Function for C12orf71 Gene
Phenotypes From GWAS Catalog for C12orf71 Gene
Phenotypes for C12orf71 Gene
- MGI mutant phenotypes for C12orf71:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for C12orf71:
Animal Models for C12orf71 Gene
- MGI Knock Outs for C12orf71:
-
- 1700034J05Rik 1700034J05Rik<tm1b(KOMP)Wtsi>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for C12orf71 - Select products 50% OFF >
- * C12orf71 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for C12orf71
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for C12orf71
-
Santa Cruz Biotechnology (SCBT) CRISPR for C12orf71
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for C12orf71
- Browse OriGene Inhibitory RNA Products For C12orf71
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C12orf71
Clone Products
- Applied Biological Materials (abm): Clones for C12orf71 - Select products 50% OFF >
- * C12orf71 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene ORF clones in human for C12orf71
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for C12orf71
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for C12orf71
Cell Line Products
-
Horizon Cell Lines for C12orf71
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for C12orf71 Gene
Localization for C12orf71 Gene
| Compartment | Confidence |
|---|---|
| nucleus | 2 |
| cytosol | 2 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for C12orf71 Gene
Transcripts for C12orf71 Gene
mRNA/cDNA for C12orf71 Gene
- 1 REFSEQ mRNAs :
- 1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000429849 957 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for C12orf71 - Select products 50% OFF >
- * C12orf71 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for C12orf71
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for C12orf71
-
Santa Cruz Biotechnology (SCBT) CRISPR for C12orf71
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for C12orf71
- Browse OriGene Inhibitory RNA Products For C12orf71
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C12orf71
Clone Products
- Applied Biological Materials (abm): Clones for C12orf71 - Select products 50% OFF >
- * C12orf71 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene ORF clones in human for C12orf71
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for C12orf71
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for C12orf71
Relevant External Links for C12orf71 Gene
- GeneLoc Exon Structure for
- C12orf71
Expression for C12orf71 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Testis (Reproductive System)
- Mature Sertoli Cells Seminiferous Tubules
mRNA differential expression in normal tissues according to GTEx for C12orf71 Gene
This gene is overexpressed in Testis (x12.1).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C12orf71 Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for C12orf71
SOURCE GeneReport for Unigene cluster for C12orf71 Gene:
Hs.334003Primer Products
-
OriGene qPCR primer pairs for C12orf71
Gene Expression Assay Products
No data available for Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C12orf71 Gene
Orthologs for C12orf71 Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | C12H12orf71 30 |
|
||
| C12orf71 31 |
|
OneToOne | |||
| Dog (Canis familiaris) |
Mammalia | LOC100684484 30 |
|
||
| C12orf71 31 |
|
OneToOne | |||
| Cow (Bos Taurus) |
Mammalia | C5H12orf71 30 |
|
||
| C12orf71 31 |
|
OneToOne | |||
| Mouse (Mus musculus) |
Mammalia | 1700034J05Rik 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | LOC690784 30 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | C12orf71 31 |
|
OneToOne |
- Species where no ortholog for C12orf71 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
- Zebrafish (Danio rerio)
Paralogs for C12orf71 Gene
Pseudogenes.org Pseudogenes for C12orf71 Gene
No data available for Paralogs for C12orf71 Gene
Variants for C12orf71 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for C12orf71 Gene
| SNP ID | Clinical significance and condition | Chr 12 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs708167 | - | p.Ile140Val |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv2417n54 | CNV | gain | 21841781 |
| esv2745664 | CNV | deletion | 23290073 |
| nsv557805 | CNV | loss | 21841781 |
| nsv832356 | CNV | gain | 17160897 |
Residual Variation Intolerance Score:
73.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
5.54;
72.07% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for C12orf71 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- C12orf71
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C12orf71 Gene
Disorders for C12orf71 Gene
Additional Disease Information for C12orf71
- Genetic Association Database
- (GAD)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No disorders were found for C12orf71 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C12orf71 Gene
Publications for C12orf71 Gene
- The finished DNA sequence of human chromosome 12. (PMID: 16541075) Scherer SE … Baylor College of Medicine Human Genome Sequencing Center Sequence Production Team (Nature 2006) 4
- The sequence of the human genome. (PMID: 11181995) Venter JC … Zhu X (Science (New York, N.Y.) 2001) 3
ExternalLinks
Products for C12orf71 Gene
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for C12orf71
- Search Origene for MassSpec and Protein Over-expression Lysates for C12orf71
- Origene Custom Protein Services for C12orf71
- Origene shrna, sirna, and RNAi products in human, mouse, rat for C12orf71
- Browse OriGene Inhibitory RNA Products For C12orf71
- OriGene qPCR primer pairs for C12orf71
- OriGene CRISPR knockouts for C12orf71
- OriGene ORF clones in human for C12orf71
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For C12orf71
- Sino Biological Human cDNA Clone for C12orf71
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for C12orf71
- Novus Biologicals proteins for C12orf71
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Invitrogen Antibodies for C12orf71 (AFLGC-C12orf71)
- VectorBuilder Custom and pre-made DNA vectors for C12orf71 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for C12orf71 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for C12orf71 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for C12orf71 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for C12orf71
- Horizon Cell Lines for C12orf71
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for C12orf71
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for C12orf71
- Search GeneCopoeia for miRNA 3'UTR Target clone products for C12orf71
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C12orf71
Sources for C12orf71 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB