This gene shares three exons in common with another gene, LBH domain containing 1 (GeneID:79081), but the encoded protein uses a reading frame that is different from that of the LBH domain containing 1 gene. [provided by RefSeq, Nov 2017] See more...

Aliases for C11orf98 Gene

Aliases for C11orf98 Gene

  • Chromosome 11 Open Reading Frame 98 2 3 5
  • Uncharacterized Protein C11orf98 3 4
  • C11orf48 3

External Ids for C11orf98 Gene

Previous HGNC Symbols for C11orf98 Gene

  • C11orf48

Previous GeneCards Identifiers for C11orf98 Gene

  • GC11M062680
  • GC11M062705
  • GC11M062950
  • GC11M062980
  • GC11M062724
  • GC11M062736
  • GC11M062749
  • GC11M062768
  • GC11M062778
  • GC11M062802
  • GC11M062821
  • GC11M062839

Summaries for C11orf98 Gene

Entrez Gene Summary for C11orf98 Gene

  • This gene shares three exons in common with another gene, LBH domain containing 1 (GeneID:79081), but the encoded protein uses a reading frame that is different from that of the LBH domain containing 1 gene. [provided by RefSeq, Nov 2017]

GeneCards Summary for C11orf98 Gene

C11orf98 (Chromosome 11 Open Reading Frame 98) is a Protein Coding gene. An important paralog of this gene is ENSG00000255432.

Additional gene information for C11orf98 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for C11orf98 Gene

Genomics for C11orf98 Gene

GeneHancer (GH) Regulatory Elements for C11orf98 Gene

Promoters and enhancers for C11orf98 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11J062664 Promoter/Enhancer 2 EPDnew Ensembl ENCODE CraniofacialAtlas 750.6 -0.7 -725 4.3 SIN3A SP1 ZBTB40 FOXA1 MLX RBPJ POLR2A NR2F6 CREB1 HCFC1 CSKMT C11orf98 ENSG00000255432 SNORA57 lnc-C11orf98-1 lnc-UQCC3-1 LBHD1 EML3 NXF1 GANAB
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around C11orf98 on UCSC Golden Path with GeneCards custom track

Genomic Locations for C11orf98 Gene

Genomic Locations for C11orf98 Gene
chr11:62,662,816-62,665,217
(GRCh38/hg38)
Size:
2,402 bases
Orientation:
Minus strand

Genomic View for C11orf98 Gene

Genes around C11orf98 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C11orf98 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C11orf98 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C11orf98 Gene

Proteins for C11orf98 Gene

  • Protein details for C11orf98 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    E9PRG8-CK098_HUMAN
    Recommended name:
    Uncharacterized protein C11orf98
    Protein Accession:
    E9PRG8
    Secondary Accessions:
    • A0A0B4J220

    Protein attributes for C11orf98 Gene

    Size:
    123 amino acids
    Molecular mass:
    14234 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C11orf98 Gene

Post-translational modifications for C11orf98 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C11orf98 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C11orf98 Gene

Domains & Families for C11orf98 Gene

Gene Families for C11orf98 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for C11orf98 Gene

InterPro:
ProtoNet:
genes like me logo Genes that share domains with C11orf98: view

No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for C11orf98 Gene

Function for C11orf98 Gene

Phenotypes From GWAS Catalog for C11orf98 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C11orf98 Gene

Localization for C11orf98 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for C11orf98 Gene

Pathways & Interactions for C11orf98 Gene

PathCards logo

SuperPathways for C11orf98 Gene

No Data Available

Interacting Proteins for C11orf98 Gene

STRING Interaction Network Preview (showing top 1 STRING interactants - click image to see details)
STRING Interaction Network
Selected Interacting proteins: ENSP00000432523 E9PRG8-CK098_HUMAN for C11orf98 Gene via STRING IID

Gene Ontology (GO) - Biological Process for C11orf98 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C11orf98 Gene

Drugs & Compounds for C11orf98 Gene

No Compound Related Data Available

Transcripts for C11orf98 Gene

mRNA/cDNA for C11orf98 Gene

(1) REFSEQ mRNAs :
(6) Additional mRNA sequences :
(3) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for C11orf98 Gene

No ASD Table

Relevant External Links for C11orf98 Gene

GeneLoc Exon Structure for
C11orf98
ECgene alternative splicing isoforms for
C11orf98

Expression for C11orf98 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

NURSA nuclear receptor signaling pathways regulating expression of C11orf98 Gene:

C11orf98
genes like me logo Genes that share expression patterns with C11orf98: view

No data available for mRNA expression in normal human tissues , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C11orf98 Gene

Orthologs for C11orf98 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C11orf98 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia C29H11orf48 32
  • 90.24 (n)
mouse
(Mus musculus)
Mammalia 1810009A15Rik 17 32
  • 84.55 (n)
rat
(Rattus norvegicus)
Mammalia LOC690349 32
  • 81.27 (n)
tropical clawed frog
(Silurana tropicalis)
Amphibia c11orf48 32
  • 63.59 (n)
Species where no ortholog for C11orf98 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C11orf98 Gene

ENSEMBL:
Gene Tree for C11orf98 (if available)
TreeFam:
Gene Tree for C11orf98 (if available)

Paralogs for C11orf98 Gene

Paralogs for C11orf98 Gene

Pseudogenes.org Pseudogenes for C11orf98 Gene

genes like me logo Genes that share paralogs with C11orf98: view

Variants for C11orf98 Gene

Sequence variations from dbSNP and Humsavar for C11orf98 Gene

SNP ID Clin Chr 11 pos Variation AA Info Type
rs1001041985 -- 62,662,455(-) T/C downstream_transcript_variant
rs1003009191 -- 62,665,794(-) C/T upstream_transcript_variant
rs1003195972 -- 62,664,525(-) T/C intron_variant
rs1003659267 -- 62,664,236(-) T/C intron_variant
rs1005090602 -- 62,666,935(-) G/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for C11orf98 Gene

Variant ID Type Subtype PubMed ID
esv3547885 CNV deletion 23714750
nsv555174 CNV gain 21841781
nsv832182 CNV gain+loss 17160897

Additional Variant Information for C11orf98 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C11orf98

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for C11orf98 Gene

Disorders for C11orf98 Gene

Additional Disease Information for C11orf98

No disorders were found for C11orf98 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C11orf98 Gene

Publications for C11orf98 Gene

  1. Identification of Microprotein-Protein Interactions via APEX Tagging. (PMID: 28589727) Chu Q … Saghatelian A (Biochemistry 2017) 2 3 56
  2. Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function. (PMID: 29467282) Heidelberger JB … Beli P (EMBO reports 2018) 3 56
  3. Quantitative mapping of RNA-mediated nuclear estrogen receptor β interactome in human breast cancer cells. (PMID: 29509190) Giurato G … Tarallo R (Scientific data 2018) 3 56
  4. An AP-MS- and BioID-compatible MAC-tag enables comprehensive mapping of protein interactions and subcellular localizations. (PMID: 29568061) Liu X … Varjosalo M (Nature communications 2018) 3 56
  5. PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation. (PMID: 30209976) Choi J … Busino L (Cell cycle (Georgetown, Tex.) 2018) 3 56

Products for C11orf98 Gene

Sources for C11orf98 Gene