C11orf96 Gene (Protein Coding)

Chromosome 11 Open Reading Frame 96

GC11P043947
GIFtS:
27
See more...

Aliases for C11orf96 Gene

Aliases for C11orf96 Gene

  • Chromosome 11 Open Reading Frame 96 2 3 5
  • AG2 2 3 4
  • Uncharacterized Protein C11orf96 3 4
  • Protein Ag2 Homolog 3 4
  • C11orf96 5

External Ids for C11orf96 Gene

Previous GeneCards Identifiers for C11orf96 Gene

  • GC11P043673

Summaries for C11orf96 Gene

GeneCards Summary for C11orf96 Gene

C11orf96 (Chromosome 11 Open Reading Frame 96) is a Protein Coding gene.

Additional gene information for C11orf96 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for C11orf96 Gene

Genomics for C11orf96 Gene

GeneHancer (GH) Regulatory Elements Pubs

Download GeneHancer 2017 data
Promoters and enhancers for C11orf96 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around C11orf96 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for C11orf96

Genomic Locations for C11orf96 Gene

Genomic Locations for C11orf96 Gene
chr11:43,925,342-43,943,878
(GRCh38/hg38)
Size:
18,537 bases
Orientation:
Plus strand
chr11:43,946,892-43,965,888
(GRCh37/hg19)
Size:
18,997 bases
Orientation:
Plus strand

Genomic View for C11orf96 Gene

Genes around C11orf96 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C11orf96 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C11orf96 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for C11orf96 Gene

Proteins for C11orf96 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

  • Protein details for C11orf96 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q7Z7L8-CK096_HUMAN
    Recommended name:
    Uncharacterized protein C11orf96
    Protein Accession:
    Q7Z7L8

    Protein attributes for C11orf96 Gene

    Size:
    435 amino acids
    Molecular mass:
    46114 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C11orf96 Gene

Protein Expression for C11orf96 Gene

See protein expression from ProteomicsDB, MOPED, PaxDb, and MaxQB

Post-translational modifications for C11orf96 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C11orf96 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C11orf96 Gene

Domains & Families for C11orf96 Gene

Gene Families for C11orf96 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for C11orf96 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for C11orf96 Gene

GenScript: Design optimal peptide antigens:
  • Protein Ag2 homolog (CK096_HUMAN)
genes like me logo Genes that share domains with C11orf96: view

No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for C11orf96 Gene

Function for C11orf96 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Phenotypes From GWAS Catalog for C11orf96 Gene

Phenotypes for C11orf96 Gene

GenomeRNAi human phenotypes for C11orf96:
genes like me logo Genes that share phenotypes with C11orf96: view

Animal Model Products

CRISPR Products

miRNA for C11orf96 Gene

miRTarBase miRNAs that target C11orf96

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C11orf96

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C11orf96 Gene

Localization for C11orf96 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C11orf96 gene
Compartment Confidence
extracellular 2
nucleus 2
cytosol 2
mitochondrion 1
peroxisome 0

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (2)
  • Focal adhesion sites (2)
  • Nucleoplasm (2)
See all subcellular structures

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C11orf96 Gene

Pathways & Interactions for C11orf96 Gene

PathCards logo

SuperPathways for C11orf96 Gene

No Data Available

Interacting Proteins for C11orf96 Gene

Gene Ontology (GO) - Biological Process for C11orf96 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C11orf96 Gene

Drugs & Compounds for C11orf96 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for C11orf96 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for C11orf96 Gene

1 REFSEQ mRNAs :
1 NCBI additional mRNA sequence :
2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C11orf96

Alternative Splicing Database (ASD) splice patterns (SP) for C11orf96 Gene

No ASD Table

Relevant External Links for C11orf96 Gene

GeneLoc Exon Structure for
C11orf96

Expression for C11orf96 Gene

Products:

  1. Primer
  2. Gene Expression Assay

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for C11orf96 Gene

mRNA expression in normal human tissues for C11orf96 Gene
mRNA expression by GTEx for C11orf96 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for C11orf96 Gene

This gene is overexpressed in Gallbladder (16.5), Liver, secretome (14.1), Heart (9.6), Testis (8.0), and Uterus (7.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C11orf96 Gene



Protein tissue co-expression partners for C11orf96 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for C11orf96

SOURCE GeneReport for Unigene cluster for C11orf96 Gene:

Hs.530443

Evidence on tissue expression from TISSUES for C11orf96 Gene

  • Lung(3)
  • Kidney(2.8)
genes like me logo Genes that share expression patterns with C11orf96: view

Primer Products

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for C11orf96 Gene

Orthologs for C11orf96 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C11orf96 Gene

Organism Taxonomy Gene Similarity Type Details
Cow
(Bos Taurus)
 Mammalia C15H11orf96 30
  • 96.42 (n)
Mouse
(Mus musculus)
 Mammalia Gm13889 30 17
  • 95.59 (n)
Rat
(Rattus norvegicus)
 Mammalia RGD1564664 30
  • 93.66 (n)
Chicken
(Gallus gallus)
 Aves C5H11ORF96 30
  • 85.28 (n)
Tropical Clawed Frog
(Silurana tropicalis)
 Amphibia LOC100495977 30
  • 73.94 (n)
Zebrafish
(Danio rerio)
 Actinopterygii LOC100330987 30
  • 63.37 (n)
C25H11orf96 31
  • 54 (a)
 OneToOne
Species where no ortholog for C11orf96 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for C11orf96 Gene

ENSEMBL:
Gene Tree for C11orf96 (if available)
TreeFam:
Gene Tree for C11orf96 (if available)

Paralogs for C11orf96 Gene

No data available for Paralogs for C11orf96 Gene

Variants for C11orf96 Gene

Products:

  1. SNP Genotyping and Copy Number Assay

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for C11orf96 Gene

SNP ID Clinical significance and condition Chr 11 pos Variation AA Info Type
rs12796438 - p.Arg110Ser
rs12796667 - p.Arg144Cys
rs12797684 - p.Ser47Pro
rs12798337 - p.Phe151Ser
rs1973717 - p.Thr26Ala

Additional dbSNP identifiers (rs#s) for C11orf96 Gene

Structural Variations from Database of Genomic Variants (DGV) for C11orf96 Gene

Variant ID Type Subtype PubMed ID
dgv1109n100 CNV gain 25217958
esv3626156 CNV gain 21293372
nsv832138 CNV gain 17160897

Variation tolerance for C11orf96 Gene

Gene Damage Index Score: 8.43; 85.64% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for C11orf96 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C11orf96

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C11orf96 Gene

Disorders for C11orf96 Gene

Additional Disease Information for C11orf96

Genetic Association Database
(GAD)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform

No disorders were found for C11orf96 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C11orf96 Gene

Publications for C11orf96 Gene

  1. An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. (PMID: 24275569) Bian Y … Zou H (Journal of proteomics 2014) 4
  2. Toward a comprehensive characterization of a human cancer cell phosphoproteome. (PMID: 23186163) Zhou H … Mohammed S (Journal of proteome research 2013) 4
  3. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PMID: 21406692) Rigbolt KT … Blagoev B (Science signaling 2011) 4
  4. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor TD … Sakaki Y (Nature 2006) 4
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4

ExternalLinks

View latest publications for C11orf96 gene in Mastermind

Products for C11orf96 Gene

Sources for C11orf96 Gene