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Aliases for C11orf80 Gene
Aliases for C11orf80 Gene
External Ids for C11orf80 Gene
- HGNC: 26197
- Entrez Gene: 79703
- Ensembl: ENSG00000173715
- OMIM: 616109
- UniProtKB: Q8N6T0
Previous GeneCards Identifiers for C11orf80 Gene
- GC11P066269
- GC11P066512
- GC11P062840
Summaries for C11orf80 Gene
GeneCards Summary for C11orf80 Gene
C11orf80 (Chromosome 11 Open Reading Frame 80) is a Protein Coding gene. Diseases associated with C11orf80 include Hydatidiform Mole, Recurrent, 4 and Hydatidiform Mole, Recurrent, 1.
UniProtKB/Swiss-Prot Summary for C11orf80 Gene
-
[Isoform 3]: Component of a topoisomerase 6 complex specifically required for meiotic recombination. Together with SPO11, mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination. The complex promotes relaxation of negative and positive supercoiled DNA and DNA decatenation through cleavage and ligation cycles.
Additional gene information for C11orf80 Gene
- HGNC(26197)
- Entrez Gene(79703)
- Ensembl(ENSG00000173715)
- OMIM(616109)
- UniProtKB(Q8N6T0)
- Open Targets Platform(ENSG00000173715)
- Monarch Initiative
- Search for C11orf80 at DataMed
- Search for C11orf80 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for C11orf80 Gene
Genomics for C11orf80 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for C11orf80 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around C11orf80 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for C11orf80
- Top Transcription factor binding sites by QIAGEN in the C11orf80 gene promoter:
-
- AP-2alpha
- AP-2alphaA
- AP-2beta
- AP-4
- GR
- GR-alpha
- LCR-F1
- RSRFC4
- Sox9
- Spz1
Genomic Locations for C11orf80 Gene
Genomic Locations for C11orf80 Gene
- chr11:66,744,451-66,843,516
- (GRCh38/hg38)
- Size:
- 99,066 bases
- Orientation:
- Plus strand
- chr11:66,511,922-66,610,987
- (GRCh37/hg19)
- Size:
- 99,066 bases
- Orientation:
- Plus strand
Genomic View for C11orf80 Gene
Genes around C11orf80 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 11q13.2 by HGNC
- 11q13.2 by Entrez Gene
- 11q13.2 by Ensembl
C11orf80 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for C11orf80 Gene
Proteins for C11orf80 Gene
-
Protein details for C11orf80 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8N6T0-TO6BL_HUMAN
- Recommended name:
- Type 2 DNA topoisomerase 6 subunit B-like
- Protein Accession:
- Q8N6T0
- Q9H677
Protein attributes for C11orf80 Gene
- Size:
- 577 amino acids
- Molecular mass:
- 64047 Da
- Quaternary structure:
-
- [Isoform 3]: Heterotetramer of SPO11 and 2 TOP6BL chains. Interacts with SPO11.
- SequenceCaution:
-
- Sequence=AAH28240.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305}; Sequence=BAB15387.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
- Miscellaneous:
-
- Expansion of a polymorphic CGG repeat within the 5'-UTR of this gene may be the cause of folate-sensitive fragile site FRA11A. The expansion is identified in the 15-year-old proband with mental retardation as well as in phenotypically normal members of the family.
- [Isoform 1]: Contains a signal peptide sequence at position 1-23.
Protein Expression for C11orf80 Gene
Post-translational modifications for C11orf80 Gene
Other Protein References for C11orf80 Gene
Antibody Products
- Creative Diagnostics Anti-C11ORF80 (aa 40-137) polyclonal antibody
- Novus Biologicals Antibodies for C11orf80
- Invitrogen Antibodies for C11orf80 (AFLGC-C11orf80)
- antibodies-online: Show 4 available C11ORF80 Antibodies ranked by validation data
Protein Products
-
OriGene Purified Proteins for C11orf80
- Search Origene for MassSpec and Protein Over-expression Lysates for C11orf80
- Origene Custom Protein Services for C11orf80
No data available for DME Specific Peptides for C11orf80 Gene
Domains & Families for C11orf80 Gene
Gene Families for C11orf80 Gene
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for C11orf80 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for C11orf80 Gene
- GenScript: Design optimal peptide antigens:
-
- cDNA FLJ55941 (B4DXL1_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q8N6T0UniProtKB/Swiss-Prot:
TO6BL_HUMAN :- [Isoform 3]: Despite a weak sequence similarity, retains most of the structural features of the ancestral archaeal Top6B subunit (AC O05207), including the transducer domain that interacts with the SPO11 subunit and the ATP-binding fold, also named GHKL fold.
- Belongs to the TOP6B-like family.
- Domain:
-
- [Isoform 3]: Despite a weak sequence similarity, retains most of the structural features of the ancestral archaeal Top6B subunit (AC O05207), including the transducer domain that interacts with the SPO11 subunit and the ATP-binding fold, also named GHKL fold.
- Family:
-
- Belongs to the TOP6B-like family.
Function for C11orf80 Gene
Molecular function for C11orf80 Gene
- UniProtKB/Swiss-Prot Function:
- [Isoform 3]: Component of a topoisomerase 6 complex specifically required for meiotic recombination. Together with SPO11, mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination. The complex promotes relaxation of negative and positive supercoiled DNA and DNA decatenation through cleavage and ligation cycles.
Phenotypes From GWAS Catalog for C11orf80 Gene
Phenotypes for C11orf80 Gene
- MGI mutant phenotypes for C11orf80:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for C11orf80:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for C11orf80 - Select products 50% OFF >
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-
OriGene CRISPR knockouts for C11orf80
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for C11orf80
-
Santa Cruz Biotechnology (SCBT) CRISPR for C11orf80
miRNA for C11orf80 Gene
- miRTarBase miRNAs that target C11orf80
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for C11orf80
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Clone Products
- Applied Biological Materials (abm): Clones for C11orf80 - Select products 50% OFF >
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- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for C11orf80
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for C11orf80
Cell Line Products
-
Horizon Cell Lines for C11orf80
No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C11orf80 Gene
Localization for C11orf80 Gene
Subcellular locations from UniProtKB/Swiss-Prot for C11orf80 Gene
- Chromosome. Note=Localizes to meiotic chromosomes. {ECO:0000250 UniProtKB:J3QMY9}.
| Compartment | Confidence |
|---|---|
| cytoskeleton | 2 |
| nucleus | 2 |
| mitochondrion | 1 |
| cytosol | 1 |
| plasma membrane | 0 |
| peroxisome | 0 |
| endoplasmic reticulum | 0 |
| golgi apparatus | 0 |
- Centrosome (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005694 | chromosome | IEA | -- |
Pathways & Interactions for C11orf80 Gene
Interacting Proteins for C11orf80 Gene
| Symbol | External ID(s) | Details |
|---|---|---|
| SPO11 |
GPS-Prot Interaction Network for C11orf80
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007131 | reciprocal meiotic recombination | IBA,ISS | -- |
| GO:0042138 | meiotic DNA double-strand break formation | IBA,ISS | -- |
| GO:0051321 | meiotic cell cycle | IEA | -- |
No data available for Pathways by source and SIGNOR curated interactions for C11orf80 Gene
Transcripts for C11orf80 Gene
mRNA/cDNA for C11orf80 Gene
- 2 REFSEQ mRNAs :
- 6 NCBI additional mRNA sequence :
- 19 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000534325 583 nts (view in UCSC)
- ENST00000524551 548 nts (view in UCSC)
- ENST00000525908 2135 nts (view in UCSC)
- ENST00000527634 1666 nts (view in UCSC)
- ENST00000527368 812 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for C11orf80 - Select products 50% OFF >
- * C11orf80 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for C11orf80
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for C11orf80
-
Santa Cruz Biotechnology (SCBT) CRISPR for C11orf80
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for C11orf80
- Browse OriGene Inhibitory RNA Products For C11orf80
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C11orf80
Clone Products
- Applied Biological Materials (abm): Clones for C11orf80 - Select products 50% OFF >
- * C11orf80 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for C11orf80
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for C11orf80
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | ^ | 9a | · | 9b | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13a | · | 13b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | ||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | ||||||||||||||||||||||||||||||||||||
| SP4: | |||||||||||||||||||||||||||||||||||||||
| SP5: | |||||||||||||||||||||||||||||||||||||||
| SP6: | - | ||||||||||||||||||||||||||||||||||||||
| SP7: | - | - | - | ||||||||||||||||||||||||||||||||||||
| SP8: |
Relevant External Links for C11orf80 Gene
- GeneLoc Exon Structure for
- C11orf80
Expression for C11orf80 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Thymus (Hematopoietic System)
- Double Positive Thymocytes Thymus
-
Blood (Cardiovascular System)
- Double Positive Thymocytes Thymus
This gene is overexpressed in Tlymphocyte (46.7) and Heart (22.3).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C11orf80 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for C11orf80
SOURCE GeneReport for Unigene cluster for C11orf80 Gene:
Hs.292088mRNA Expression by UniProt/SwissProt for C11orf80 Gene:
Q8N6T0-TO6BL_HUMAN
Tissue specificity:
Detected in lung, spleen,colon and in skeletal muscle. Expressed in the ovaries, Fallopian tubes and uterus (PubMed:30388401).
Evidence on tissue expression from TISSUES for C11orf80 Gene
- Nervous system(4.3)
Primer Products
-
OriGene qPCR primer pairs for C11orf80
-
OriGene qPCR primer pairs and template standards for C11orf80
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for C11orf80 Gene
Orthologs for C11orf80 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | C11H11orf80 30 |
|
||
| C11orf80 31 |
|
OneToOne | |||
| Cow (Bos Taurus) |
Mammalia | C29H11orf80 30 |
|
||
| C11orf80 31 |
|
OneToOne | |||
| Dog (Canis familiaris) |
Mammalia | C18H11orf80 30 |
|
||
| C11orf80 31 |
|
OneToOne | |||
| Mouse (Mus musculus) |
Mammalia | Gm960 30 17 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | C11orf80 31 |
|
OneToOne | |
| Zebrafish (Danio rerio) |
Actinopterygii | zgc:195212 30 |
|
||
| C14H11orf80 31 |
|
OneToOne |
- Species where no ortholog for C11orf80 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Oppossum (Monodelphis domestica)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rat (Rattus norvegicus)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Paralogs for C11orf80 Gene
(42) SIMAP similar genes for C11orf80 Gene using alignment to 13 proteins:
- CK080_HUMAN
- B4DXL1_HUMAN
- C9JZP8_HUMAN
- E9PIE7_HUMAN
- E9PJS1_HUMAN
- E9PKM2_HUMAN
- E9PMI8_HUMAN
- E9PMU2_HUMAN
- E9PNG9_HUMAN
- H0YD22_HUMAN
- H0YD55_HUMAN
- H0YDL3_HUMAN
- H0YE21_HUMAN
No data available for Paralogs for C11orf80 Gene
Variants for C11orf80 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for C11orf80 Gene
| SNP ID | Clinical significance and condition | Chr 11 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 791631 | Benign: not provided | 66,842,947(+) | G/A | MISSENSE_VARIANT | |
| rs1449401018 | Uncertain Significance: HYDATIDIFORM MOLE, RECURRENT, 4 | 66,822,606(+) | T/C | MISSENSE_VARIANT | |
| rs779402951 | Pathogenic: HYDATIDIFORM MOLE, RECURRENT, 4 | 66,801,039(+) | A/AT | NONSENSE | |
| VAR_082606 | Hydatidiform mole, recurrent, 4 (HYDM4) [MIM:618432] | p.Ser401Pro |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2665794 | CNV | deletion | 23128226 |
| esv2744640 | CNV | deletion | 23290073 |
| esv2744642 | CNV | deletion | 23290073 |
| esv3547920 | CNV | deletion | 23714750 |
| esv3626698 | CNV | loss | 21293372 |
| nsv1134146 | CNV | deletion | 24896259 |
| nsv364 | CNV | insertion | 18451855 |
| nsv468602 | CNV | loss | 19166990 |
| nsv508638 | CNV | deletion | 20534489 |
| nsv516087 | CNV | gain | 19592680 |
| nsv555225 | CNV | loss | 21841781 |
| nsv555226 | CNV | gain | 21841781 |
| nsv951020 | CNV | deletion | 24416366 |
Residual Variation Intolerance Score:
34.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.35;
41.79% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for C11orf80 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- C11orf80
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C11orf80 Gene
Disorders for C11orf80 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| hydatidiform mole, recurrent, 4 |
|
|
| hydatidiform mole, recurrent, 1 |
|
|
Search C11orf80 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
TO6BL_HUMAN- Hydatidiform mole, recurrent, 4 (HYDM4) [MIM:618432]: A disorder characterized by excessive trophoblast development that produces a growing mass of tissue inside the uterus at the beginning of a pregnancy. It leads to abnormal pregnancies with no embryo, and cystic degeneration of the chorionic villi. {ECO:0000269 PubMed:30388401}. Note=The disease may be caused by mutations affecting the gene represented in this entry.
Additional Disease Information for C11orf80
- Genetic Association Database
- (GAD)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for Genatlas for C11orf80 Gene
Publications for C11orf80 Gene
- The TopoVIB-Like protein family is required for meiotic DNA double-strand break formation. (PMID: 26917764) Robert T … de Massy B (Science (New York, N.Y.) 2016) 2 3 4
- The molecular basis of the folate-sensitive fragile site FRA11A at 11q13. (PMID: 18160775) Debacker K … Kooy F (Cytogenetic and genome research 2007) 2 3 4
- Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. (PMID: 21926972) Psychiatric GWAS Consortium Bipolar Disorder Working Group (Nature genetics 2011) 3 41
- Causative Mutations and Mechanism of Androgenetic Hydatidiform Moles. (PMID: 30388401) Nguyen NMP … Slim R (American journal of human genetics 2018) 4
- BRCA2 mediates centrosome cohesion via an interaction with cytoplasmic dynein. (PMID: 27433848) Malik S … Nakanishi A (Cell cycle (Georgetown, Tex.) 2016) 3
ExternalLinks
Products for C11orf80 Gene
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- Custom Assay Services
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- Origene Custom Protein Services for C11orf80
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- Browse OriGene Inhibitory RNA Products For C11orf80
- OriGene qPCR primer pairs for C11orf80
- OriGene qPCR primer pairs and template standards for C11orf80
- OriGene CRISPR knockouts for C11orf80
- OriGene ORF clones in human for C11orf80
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For C11orf80
- Sino Biological Human cDNA Clone for C11orf80
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- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for C11orf80
- Novus Biologicals proteins and lysates for C11orf80
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Invitrogen Antibodies for C11orf80 (AFLGC-C11orf80)
- VectorBuilder Custom and pre-made DNA vectors for C11orf80 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for C11orf80 (ie. lentivirus, AAV, adenovirus)
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- VectorBuilder Virus packaging for C11orf80 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for C11orf80
- antibodies-online: Show 4 available C11ORF80 Antibodies ranked by validation data
- antibodies-online: Search results for available C11ORF80 related products ranked by validation data
- antibodies-online: Search results for available C11ORF80 related products ranked by validation data
- Horizon Cell Lines for C11orf80
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for C11orf80
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- Search GeneCopoeia for miRNA 3'UTR Target clone products for C11orf80
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C11orf80
Sources for C11orf80 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
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