Aliases for C11orf74 Gene
External Ids for C11orf74 Gene
Previous GeneCards Identifiers for C11orf74 Gene
This gene encodes a protein that was identified as a cellular interacting partner of non-structural protein 10 of the severe acute respiratory syndrome coronavirus (SARS-CoV). The encoded protein may function as a negative regulator of transcription. There is a pseudogene for this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]
GeneCards Summary for C11orf74 Gene
C11orf74 (Chromosome 11 Open Reading Frame 74) is a Protein Coding gene. Diseases associated with C11orf74 include Recombinase Activating Gene 2 Deficiency and Combined Immunodeficiency With Skin Granulomas.
UniProtKB/Swiss-Prot Summary for C11orf74 Gene
Seems to play a role in ciliary BBSome localization, maybe through interaction with IFT-A complex.