Aliases for C11orf71 Gene
Aliases for C11orf71 Gene
External Ids for C11orf71 Gene
- HGNC: 25937
- Entrez Gene: 54494
- Ensembl: ENSG00000180425
- UniProtKB: Q6IPW1
Previous GeneCards Identifiers for C11orf71 Gene
- GC11M113767
- GC11M114262
- GC11M110190
Summaries for C11orf71 Gene
GeneCards Summary for C11orf71 Gene
C11orf71 (Chromosome 11 Open Reading Frame 71) is a Protein Coding gene.
Additional gene information for C11orf71 Gene
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C11orf71 Gene
Genomics for C11orf71 Gene
GeneHancer (GH) Regulatory Elements for C11orf71 Gene
Promoters and enhancers for C11orf71 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around C11orf71 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for C11orf71 Gene
Genomic Locations for C11orf71 Gene
- chr11:114,391,443-114,400,550
- (GRCh38/hg38)
- Size:
- 9,108 bases
- Orientation:
- Minus strand
- chr11:114,262,165-114,271,139
- (GRCh37/hg19)
Genomic View for C11orf71 Gene
Genes around C11orf71 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 11q23.2 by Entrez Gene
- 11q23.2 by HGNC
- 11q23.2 by Ensembl
C11orf71 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for C11orf71 Gene
Proteins for C11orf71 Gene
-
Protein details for C11orf71 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q6IPW1-CK071_HUMAN
- Recommended name:
- Uncharacterized protein C11orf71
- Protein Accession:
- Q6IPW1
- Q6IAD3
- Q9NXX1
Protein attributes for C11orf71 Gene
- Size:
- 123 amino acids
- Molecular mass:
- 13249 Da
- Quaternary structure:
- No Data Available
Protein Expression for C11orf71 Gene
Post-translational modifications for C11orf71 Gene
Other Protein References for C11orf71 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for C11orf71
- Invitrogen Antibodies for C11orf71
- Search GeneTex for Antibodies for C11orf71
Protein Products
-
OriGene Purified Proteins for C11orf71
- Search Origene for MassSpec and Protein Over-expression Lysates for C11orf71
- Origene Custom Protein Services for C11orf71
- Novus Biologicals proteins for C11orf71
- Search GeneTex for Proteins for C11orf71
Assay Products
No data available for DME Specific Peptides for C11orf71 Gene
Domains & Families for C11orf71 Gene
Gene Families for C11orf71 Gene
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Graphical View of Domain Structure for InterPro Entry
No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C11orf71 Gene
Function for C11orf71 Gene
Phenotypes From GWAS Catalog for C11orf71 Gene
Phenotypes for C11orf71 Gene
- GenomeRNAi human phenotypes for C11orf71:
-
- Decreased viability after ionizing radiation
- Decreased ionizing radiation sensitivity
- Decreased viability
- no effect
- Increased vaccinia virus (VACV) infection
- Mildly decreased CFP-tsO45G cell surface transport
- Decreased hepcidin::fluc mRNA expression
- Decreased NF-kappaB reporter expression
- Increased viability
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for C11orf71
-
CRISPR Products
-
OriGene CRISPR knockouts for C11orf71
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for C11orf71
- genomics-online: gRNA clones - Search results for 53 available C11ORF71 gene related products
- Overview of 53 available C11ORF71 gene related products
- Applied Biological Materials CRISPR for C11orf71
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for C11orf71
- GenScript: Design CRISPR guide RNA sequences for C11orf71
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for C11orf71
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- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C11orf71
- genomics-online: shRNA clones - Search results for 53 available C11ORF71 gene related products
- Overview of 53 available C11ORF71 gene related products
Clone Products
- VectorBuilder custom plasmid, inducible vectors for C11orf71
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C11orf71
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for C11orf71
- Applied Biological Materials Clones for C11orf71
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for C11orf71
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C11orf71 Gene
Localization for C11orf71 Gene
| Compartment | Confidence |
|---|---|
| nucleus | 2 |
| cytosol | 2 |
| extracellular | 1 |
| mitochondrion | 1 |
- Nucleoplasm (3)
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C11orf71 Gene
Pathways & Interactions for C11orf71 Gene
No Data Available
Interacting Proteins for C11orf71 Gene
GPS-Prot Interaction Network for C11orf71
No data available for Pathways by source and SIGNOR curated interactions for C11orf71 Gene
Transcripts for C11orf71 Gene
mRNA/cDNA for C11orf71 Gene
- (111) Selected AceView cDNA sequences:
- (4) Additional mRNA sequences :
- (2) REFSEQ mRNAs :
- (2) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000325636 652 bps (uc284mzn.1)
- ENST00000623205 1980 bps (uc001pou.7)
Unigene Clusters for C11orf71 Gene
- Chromosome 11 open reading frame 71:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for C11orf71
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for C11orf71
- genomics-online: gRNA clones - Search results for 53 available C11ORF71 gene related products
- Overview of 53 available C11ORF71 gene related products
- Applied Biological Materials CRISPR for C11orf71
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for C11orf71
- GenScript: Design CRISPR guide RNA sequences for C11orf71
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for C11orf71
- Browse OriGene Inhibitory RNA Products For C11orf71
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C11orf71
- genomics-online: shRNA clones - Search results for 53 available C11ORF71 gene related products
- Overview of 53 available C11ORF71 gene related products
Clone Products
- VectorBuilder custom plasmid, inducible vectors for C11orf71
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C11orf71
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for C11orf71
- Applied Biological Materials Clones for C11orf71
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for C11orf71 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Epithelial Cells
- Fetal Matrix Cells Hair Follicle
-
Hair (Integumentary System)
- Fetal Matrix Cells Hair Follicle
-
Testis (Reproductive System)
-
Prostate (Endocrine System)
This gene is overexpressed in Heart (69.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C11orf71 Gene
NURSA nuclear receptor signaling pathways regulating expression of C11orf71 Gene:
C11orf71SOURCE GeneReport for Unigene cluster for C11orf71 Gene:
Hs.715083Primer Products
-
OriGene qPCR primer pairs and template standards for C11orf71
-
OriGene qPCR primer pairs for C11orf71
- genomics-online: primer clones - Search results for 53 available C11ORF71 gene related products
- Overview of 53 available C11ORF71 gene related products
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C11orf71 Gene
Orthologs for C11orf71 Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | C11H11orf71 33 |
|
||
| C11orf71 34 |
|
OneToOne | |||
| cow (Bos Taurus) |
Mammalia | C15H11orf71 34 33 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | RGD1563941 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Gm5617 16 34 33 |
|
||
| dog (Canis familiaris) |
Mammalia | C11orf71 34 |
|
OneToOne |
- Species where no ortholog for C11orf71 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for C11orf71 Gene
No data available for Paralogs for C11orf71 Gene
Variants for C11orf71 Gene
| SNP ID | Clin | Chr 11 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000122162 | -- | 114,400,453(-) | G/A | 5_prime_UTR_variant | |
| rs1000142686 | -- | 114,399,283(-) | G/A | 3_prime_UTR_variant, intron_variant | |
| rs1000369583 | -- | 114,392,892(-) | C/T | genic_downstream_transcript_variant, intron_variant | |
| rs1000794307 | -- | 114,401,256(-) | G/A | upstream_transcript_variant | |
| rs1001064391 | -- | 114,393,629(-) | T/C | genic_downstream_transcript_variant, intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3548365 | CNV | deletion | 23714750 |
Residual Variation Intolerance Score:
75.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.38;
27.25% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for C11orf71 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- C11orf71
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C11orf71 Gene
Disorders for C11orf71 Gene
Additional Disease Information for C11orf71
No disorders were found for C11orf71 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C11orf71 Gene
Publications for C11orf71 Gene
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 58
- Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) Oláh J … Ovádi J (The Journal of biological chemistry 2011) 3 58
- Toward an understanding of the protein interaction network of the human liver. (PMID: 21988832) Wang J … Yang X (Molecular systems biology 2011) 3 58
Products for C11orf71 Gene
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- Custom Assay Services
- OriGene Purified Proteins for C11orf71
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- OriGene qPCR primer pairs and template standards for C11orf71
- OriGene qPCR primer pairs for C11orf71
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- Sino Biological Transfection Reagent
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- Novus Biologicals Antibodies for C11orf71
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- Browse Antibodies
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- VectorBuilder custom plasmid, inducible vectors for C11orf71
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C11orf71
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneTex for Antibodies for C11orf71
- Search GeneTex for Proteins for C11orf71
- Horizon Cell Lines for C11orf71
- genomics-online: cdna clones - Search results for 53 available C11ORF71 gene related products
- Overview of 53 available C11ORF71 gene related products
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- Overview of 53 available C11ORF71 gene related products
- genomics-online: gRNA clones - Search results for 53 available C11ORF71 gene related products
- Overview of 53 available C11ORF71 gene related products
- genomics-online: primer clones - Search results for 53 available C11ORF71 gene related products
- Overview of 53 available C11ORF71 gene related products
- genomics-online: shRNA clones - Search results for 53 available C11ORF71 gene related products
- Overview of 53 available C11ORF71 gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for C11orf71
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Sources for C11orf71 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio