C11orf71 Gene (Protein Coding)

Chromosome 11 Open Reading Frame 71

GC11M114391
GIFtS:
28

Aliases for C11orf71 Gene

Aliases for C11orf71 Gene

  • Chromosome 11 Open Reading Frame 71 2 3 5
  • Uncharacterized Protein C11orf71 3 4
  • Up-Regulated In Lung Cancer 7 3
  • URLC7 3

External Ids for C11orf71 Gene

Previous GeneCards Identifiers for C11orf71 Gene

  • GC11M113767
  • GC11M114262
  • GC11M110190

Summaries for C11orf71 Gene

GeneCards Summary for C11orf71 Gene

C11orf71 (Chromosome 11 Open Reading Frame 71) is a Protein Coding gene.

Additional gene information for C11orf71 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for C11orf71 Gene

Genomics for C11orf71 Gene

GeneHancer (GH) Regulatory Elements for C11orf71 Gene

Promoters and enhancers for C11orf71 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around C11orf71 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for C11orf71

Top Transcription factor binding sites by QIAGEN in the C11orf71 gene promoter:
  • ATF-2
  • c-Jun
  • CUTL1
  • GATA-1
  • GCNF
  • GCNF-1
  • GCNF-2
  • GR
  • POU2F1
  • POU2F1a

Genomic Locations for C11orf71 Gene

Genomic Locations for C11orf71 Gene
chr11:114,391,443-114,400,550
(GRCh38/hg38)
Size:
9,108 bases
Orientation:
Minus strand
chr11:114,262,165-114,271,139
(GRCh37/hg19)
Size:
8,975 bases
Orientation:
Minus strand

Genomic View for C11orf71 Gene

Genes around C11orf71 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C11orf71 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C11orf71 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for C11orf71 Gene

Proteins for C11orf71 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

  • Protein details for C11orf71 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6IPW1-CK071_HUMAN
    Recommended name:
    Uncharacterized protein C11orf71
    Protein Accession:
    Q6IPW1
    Secondary Accessions:
    • Q6IAD3
    • Q9NXX1

    Protein attributes for C11orf71 Gene

    Size:
    123 amino acids
    Molecular mass:
    13249 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C11orf71 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C11orf71 Gene

Protein Expression for C11orf71 Gene

See protein expression from ProteomicsDB, MOPED, PaxDb, and MaxQB

Post-translational modifications for C11orf71 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C11orf71 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C11orf71 Gene

Domains & Families for C11orf71 Gene

Gene Families for C11orf71 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for C11orf71 Gene

InterPro:
ProtoNet:
genes like me logo Genes that share domains with C11orf71: view

No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for C11orf71 Gene

Function for C11orf71 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Phenotypes From GWAS Catalog for C11orf71 Gene

genes like me logo Genes that share phenotypes with C11orf71: view

Animal Model Products

CRISPR Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C11orf71 Gene

Localization for C11orf71 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C11orf71 gene
Compartment Confidence
extracellular 1
mitochondrion 1
nucleus 1
cytosol 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nucleoplasm (3)
See all subcellular structures

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C11orf71 Gene

Pathways & Interactions for C11orf71 Gene

PathCards logo

SuperPathways for C11orf71 Gene

No Data Available

Interacting Proteins for C11orf71 Gene

Selected Interacting proteins: Q6IPW1-CK071_HUMAN for C11orf71 Gene via IID

GPS-Prot Interaction Network for C11orf71
;

Gene Ontology (GO) - Biological Process for C11orf71 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C11orf71 Gene

Drugs & Compounds for C11orf71 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for C11orf71 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for C11orf71 Gene

2 REFSEQ mRNAs :
6 NCBI additional mRNA sequence :
2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for C11orf71 Gene

No ASD Table

Relevant External Links for C11orf71 Gene

GeneLoc Exon Structure for
C11orf71

Expression for C11orf71 Gene

Products:

  1. Primer
  2. Gene Expression Assay

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for C11orf71 Gene

mRNA expression in normal human tissues for C11orf71 Gene
mRNA expression by BioGPS for C11orf71 GenemRNA expression by GTEx for C11orf71 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for C11orf71 Gene

This gene is overexpressed in Heart (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C11orf71 Gene



Protein tissue co-expression partners for C11orf71 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for C11orf71

SOURCE GeneReport for Unigene cluster for C11orf71 Gene:

Hs.715083
genes like me logo Genes that share expression patterns with C11orf71: view

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C11orf71 Gene

Orthologs for C11orf71 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C11orf71 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
 Mammalia C11H11orf71 30
  • 99.09 (n)
C11orf71 31
  • 99 (a)
 OneToOne
cow
(Bos Taurus)
 Mammalia C15H11orf71 31 30
  • 79.24 (n)
 OneToOne
rat
(Rattus norvegicus)
 Mammalia RGD1563941 30
  • 75.52 (n)
mouse
(Mus musculus)
 Mammalia Gm5617 17 31 30
  • 75.22 (n)
dog
(Canis familiaris)
 Mammalia C11orf71 31
  • 59 (a)
 OneToOne
Species where no ortholog for C11orf71 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C11orf71 Gene

ENSEMBL:
Gene Tree for C11orf71 (if available)
TreeFam:
Gene Tree for C11orf71 (if available)

Paralogs for C11orf71 Gene

No data available for Paralogs for C11orf71 Gene

Variants for C11orf71 Gene

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  1. SNP Genotyping and Copy Number Assay

Additional dbSNP identifiers (rs#s) for C11orf71 Gene

Structural Variations from Database of Genomic Variants (DGV) for C11orf71 Gene

Variant ID Type Subtype PubMed ID
esv3548365 CNV deletion 23714750

Variation tolerance for C11orf71 Gene

Residual Variation Intolerance Score: 75.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.38; 27.25% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for C11orf71 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C11orf71

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for C11orf71 Gene

Disorders for C11orf71 Gene

Additional Disease Information for C11orf71

ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for C11orf71 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C11orf71 Gene

Publications for C11orf71 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 54
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 54
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 54
  4. Toward an understanding of the protein interaction network of the human liver. (PMID: 21988832) Wang J … Yang X (Molecular systems biology 2011) 3 54
  5. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) Oláh J … Ovádi J (The Journal of biological chemistry 2011) 3 54

ExternalLinks

View latest publications for C11orf71 gene in Mastermind

Products for C11orf71 Gene

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