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Aliases for C11orf71 Gene
Aliases for C11orf71 Gene
External Ids for C11orf71 Gene
- HGNC: 25937
- Entrez Gene: 54494
- Ensembl: ENSG00000180425
- UniProtKB: Q6IPW1
Previous GeneCards Identifiers for C11orf71 Gene
- GC11M113767
- GC11M114262
- GC11M110190
Summaries for C11orf71 Gene
GeneCards Summary for C11orf71 Gene
C11orf71 (Chromosome 11 Open Reading Frame 71) is a Protein Coding gene.
Additional gene information for C11orf71 Gene
- HGNC(25937)
- Entrez Gene(54494)
- Ensembl(ENSG00000180425)
- UniProtKB(Q6IPW1)
- Open Targets Platform(ENSG00000180425)
- Search for C11orf71 at DataMed
- Search for C11orf71 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for C11orf71 Gene
Genomics for C11orf71 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for C11orf71 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around C11orf71 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for C11orf71
- Top Transcription factor binding sites by QIAGEN in the C11orf71 gene promoter:
-
- ATF-2
- c-Jun
- CUTL1
- GATA-1
- GCNF
- GCNF-1
- GCNF-2
- GR
- POU2F1
- POU2F1a
Genomic Locations for C11orf71 Gene
Genomic Locations for C11orf71 Gene
- chr11:114,391,443-114,400,511
- (GRCh38/hg38)
- Size:
- 9,069 bases
- Orientation:
- Minus strand
- chr11:114,262,165-114,271,139
- (GRCh37/hg19)
- Size:
- 8,975 bases
- Orientation:
- Minus strand
Genomic View for C11orf71 Gene
Genes around C11orf71 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 11q23.2 by HGNC
- 11q23.2 by Entrez Gene
- 11q23.2 by Ensembl
C11orf71 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for C11orf71 Gene
Proteins for C11orf71 Gene
-
Protein details for C11orf71 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q6IPW1-CK071_HUMAN
- Recommended name:
- Uncharacterized protein C11orf71
- Protein Accession:
- Q6IPW1
- Q6IAD3
- Q9NXX1
Protein attributes for C11orf71 Gene
- Size:
- 123 amino acids
- Molecular mass:
- 13249 Da
- Quaternary structure:
- No Data Available
Protein Expression for C11orf71 Gene
Post-translational modifications for C11orf71 Gene
Other Protein References for C11orf71 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for C11orf71
- Invitrogen Antibodies for C11orf71 (AFLGC-C11orf71)
- antibodies-online: Show 17 available C11ORF71 Antibodies ranked by validation data
Protein Products
-
OriGene Purified Proteins for C11orf71
- Search Origene for MassSpec and Protein Over-expression Lysates for C11orf71
- Origene Custom Protein Services for C11orf71
- Novus Biologicals proteins for C11orf71
No data available for DME Specific Peptides for C11orf71 Gene
Domains & Families for C11orf71 Gene
Gene Families for C11orf71 Gene
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for C11orf71 Gene
Function for C11orf71 Gene
Phenotypes From GWAS Catalog for C11orf71 Gene
Phenotypes for C11orf71 Gene
- MGI mutant phenotypes for C11orf71:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for C11orf71:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for C11orf71 - Select products 50% OFF >
- * C11orf71 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for C11orf71
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for C11orf71
-
Santa Cruz Biotechnology (SCBT) CRISPR for C11orf71
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for C11orf71
- Browse OriGene Inhibitory RNA Products For C11orf71
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C11orf71
Clone Products
- Applied Biological Materials (abm): Clones for C11orf71 - Select products 50% OFF >
- * C11orf71 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for C11orf71
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for C11orf71
Cell Line Products
-
Horizon Cell Lines for C11orf71
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C11orf71 Gene
Localization for C11orf71 Gene
| Compartment | Confidence |
|---|---|
| extracellular | 1 |
| mitochondrion | 1 |
| nucleus | 1 |
| cytosol | 1 |
- Nucleoplasm (3)
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C11orf71 Gene
Pathways & Interactions for C11orf71 Gene
Interacting Proteins for C11orf71 Gene
No data available for Pathways by source and SIGNOR curated interactions for C11orf71 Gene
Transcripts for C11orf71 Gene
mRNA/cDNA for C11orf71 Gene
- 2 REFSEQ mRNAs :
- 6 NCBI additional mRNA sequence :
- 2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000325636 652 nts (view in UCSC)
- ENST00000623205 1980 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for C11orf71 - Select products 50% OFF >
- * C11orf71 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for C11orf71
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for C11orf71
-
Santa Cruz Biotechnology (SCBT) CRISPR for C11orf71
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for C11orf71
- Browse OriGene Inhibitory RNA Products For C11orf71
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C11orf71
Clone Products
- Applied Biological Materials (abm): Clones for C11orf71 - Select products 50% OFF >
- * C11orf71 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for C11orf71
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for C11orf71
Relevant External Links for C11orf71 Gene
- GeneLoc Exon Structure for
- C11orf71
Expression for C11orf71 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Hair (Integumentary System)
- Fetal Matrix Cells Hair Follicle
-
Epithelial Cells
- Fetal Matrix Cells Hair Follicle
-
Prostate (Endocrine System)
-
Testis (Reproductive System)
This gene is overexpressed in Heart (69.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C11orf71 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for C11orf71
SOURCE GeneReport for Unigene cluster for C11orf71 Gene:
Hs.715083Primer Products
-
OriGene qPCR primer pairs for C11orf71
-
OriGene qPCR primer pairs and template standards for C11orf71
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C11orf71 Gene
Orthologs for C11orf71 Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | C11H11orf71 30 |
|
||
| C11orf71 31 |
|
OneToOne | |||
| Cow (Bos Taurus) |
Mammalia | C15H11orf71 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | RGD1563941 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Gm5617 30 17 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | C11orf71 31 |
|
OneToOne |
- Species where no ortholog for C11orf71 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Oppossum (Monodelphis domestica)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
- Zebrafish (Danio rerio)
Paralogs for C11orf71 Gene
No data available for Paralogs for C11orf71 Gene
Variants for C11orf71 Gene
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3548365 | CNV | deletion | 23714750 |
Residual Variation Intolerance Score:
75.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.38;
27.25% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for C11orf71 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- C11orf71
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for C11orf71 Gene
Disorders for C11orf71 Gene
Additional Disease Information for C11orf71
No disorders were found for C11orf71 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C11orf71 Gene
Publications for C11orf71 Gene
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3
- Toward an understanding of the protein interaction network of the human liver. (PMID: 21988832) Wang J … Yang X (Molecular systems biology 2011) 3
- Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) Oláh J … Ovádi J (The Journal of biological chemistry 2011) 3
ExternalLinks
Products for C11orf71 Gene
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for C11orf71
- Search Origene for MassSpec and Protein Over-expression Lysates for C11orf71
- Origene Custom Protein Services for C11orf71
- Origene shrna, sirna, and RNAi products in human, mouse, rat for C11orf71
- Browse OriGene Inhibitory RNA Products For C11orf71
- OriGene qPCR primer pairs for C11orf71
- OriGene qPCR primer pairs and template standards for C11orf71
- OriGene CRISPR knockouts for C11orf71
- OriGene ORF clones in human for C11orf71
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For C11orf71
- Sino Biological Human cDNA Clone for C11orf71
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for C11orf71
- Novus Biologicals proteins for C11orf71
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Invitrogen Antibodies for C11orf71 (AFLGC-C11orf71)
- VectorBuilder Custom and pre-made DNA vectors for C11orf71 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for C11orf71 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for C11orf71 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for C11orf71 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for C11orf71
- antibodies-online: Show 17 available C11ORF71 Antibodies ranked by validation data
- antibodies-online: Search results for available C11ORF71 related products ranked by validation data
- antibodies-online: Search results for available C11ORF71 related products ranked by validation data
- Horizon Cell Lines for C11orf71
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for C11orf71
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for C11orf71
- Search GeneCopoeia for miRNA 3'UTR Target clone products for C11orf71
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C11orf71
Sources for C11orf71 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB