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Aliases for C11orf45 Gene
Data sources for C11orf45 Gene:
Subcategory (RNA class) for C11orf45 Gene
lncRNA
Aliases for C11orf45 Gene
- Chromosome 11 Open Reading Frame 45 (HGNC, NCBI Entrez Gene, Ensembl)
- Putative Uncharacterized Protein C11orf45 (UniProtKB/Swiss-Prot)
- Lnc-C11orf45-1 (LNCipedia)
- HSALNG0088130 (LncBook)
- C11orf45 (Ensembl)
- MGC35558 (HGNC)
- FLJ43646 (HGNC)
External Ids for C11orf45 Gene
- HGNC: 28584
- NCBI Entrez Gene: 219833
- Ensembl: ENSG00000174370
- UniProtKB/Swiss-Prot: Q8TAV5
Previous GeneCards Identifiers for C11orf45 Gene
- GC11M128275
- GC11M128769
- GC11M124719
Summaries for C11orf45 Gene
GeneCards Summary for C11orf45 Gene
C11orf45 (Chromosome 11 Open Reading Frame 45) is an RNA Gene, and is affiliated with the lncRNA class.
Additional gene information for C11orf45 Gene
- HGNC (28584)
- NCBI Entrez Gene (219833)
- Ensembl (ENSG00000174370)
- UniProtKB/Swiss-Prot (Q8TAV5)
- Open Targets Platform(ENSG00000174370)
- Search for C11orf45 at DataMed
- Search for C11orf45 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for C11orf45 Gene
Genomics for C11orf45 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for C11orf45 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around C11orf45 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for C11orf45
- Top Transcription factor binding sites by QIAGEN in the C11orf45 gene promoter:
-
- E47
- GATA-2
- HOXA5
- Nkx2-5
- SRY
- STAT1
- STAT1beta
- STAT2
- STAT3
- STAT4
Genomic Locations for C11orf45 Gene
Latest Assembly
- chr11:128,899,564-128,906,231
- (GRCh38/hg38)
- Size:
- 6,668 bases
- Orientation:
- Minus strand
Previous Assembly
- chr11:128,769,460-128,776,126
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 6,667 bases
- Orientation:
- Minus strand
- chr11:128,769,460-128,775,930
- (GRCh37/hg19 by Ensembl)
- Size:
- 6,471 bases
- Orientation:
- Minus strand
Genomic View for C11orf45 Gene
Genes around C11orf45 on UCSC Golden Path with GeneCards custom track
C11orf45 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path
- Cytogenetic band:
-
- 11q24.3 by HGNC
- 11q24.3 by Entrez Gene
- 11q24.3 by Ensembl
C11orf45 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for C11orf45 Gene
Proteins for C11orf45 Gene
-
Protein details for C11orf45 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8TAV5-CK045_HUMAN
- Recommended name:
- Putative uncharacterized protein C11orf45
- Protein Accession:
- Q8TAV5
- B2RAD0
Protein attributes for C11orf45 Gene
- Size:
- 145 amino acids
- Molecular mass:
- 15559 Da
- Quaternary structure:
- No Data Available
Post-translational modifications for C11orf45 Gene
Other Protein References for C11orf45 Gene
- ENSEMBL proteins:
Antibodies for research
- Novus Biologicals Antibodies for C11orf45
- Invitrogen Antibodies for C11orf45 (AFLGC-C11orf45)
- antibodies-online: Show 6 available C11ORF45 Antibodies ranked by validation data
Protein products for research
-
OriGene Purified Proteins for C11orf45
- Search Origene for MassSpec and Protein Over-expression Lysates for C11orf45
- Origene Custom Protein Services for C11orf45
Assay products for research
No data available for DME Specific Peptides for C11orf45 Gene
Domains & Families for C11orf45 Gene
Gene Families for C11orf45 Gene
- Human Protein Atlas (HPA):
-
- Predicted secreted proteins
No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for C11orf45 Gene
Function for C11orf45 Gene
Phenotypes From GWAS Catalog for C11orf45 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 32296183 |
Phenotypes for C11orf45 Gene
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for C11orf45 - Starting at $85 >
- * C11orf45 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for C11orf45
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for C11orf45
-
Santa Cruz Biotechnology (SCBT) CRISPR for C11orf45
miRNA for C11orf45 Gene
- miRTarBase miRNAs that target C11orf45
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for C11orf45
- Browse OriGene Inhibitory RNA Products For C11orf45
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C11orf45
Clone products for research
- Applied Biological Materials (abm): Clones for C11orf45 - Starting at $45 >
- * C11orf45 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for C11orf45
Cell Lines for research
-
Horizon Cell Lines for C11orf45
No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C11orf45 Gene
Localization for C11orf45 Gene
Subcellular locations from UniProtKB/Swiss-Prot for C11orf45 Gene
- Secreted.
| Compartment | Confidence |
|---|---|
| extracellular | 4 |
| cytosol | 2 |
| mitochondrion | 1 |
| nucleus | 0 |
- Cytosol (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | IEA | -- |
Transcripts for C11orf45 Gene
Non-coding RNA (ncRNA) Transcripts from RNAcentral for C11orf45 Gene
| RNAcentral Transcript ID | Subcategory | Length (nts) | # of Sources | Source Identifiers and Annotations |
|---|---|---|---|---|
| URS0001BBE58E_9606 | lncRNA | 3636 | 1 |
RefSeq: NR_169216, |
| URS0001BBE3EB_9606 | lncRNA | 3595 | 1 |
RefSeq: NR_169215, |
| URS0001BBE59D_9606 | lncRNA | 3558 | 1 |
RefSeq: NR_045767, |
| URS0001BBE644_9606 | lncRNA | 3538 | 1 |
RefSeq: NR_169217, |
| URS0000EF39E2_9606 | lncRNA | 609 | 1 |
Ensembl: ENST00000524878 (view in UCSC) , |
C11orf45 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path
Additional transcripts not in RNAcentral for C11orf45 Gene
- 3 REFSEQ mRNAs :
- 5 NCBI additional mRNA sequence :
- 1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000310799 3624 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for C11orf45 - Starting at $85 >
- * C11orf45 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for C11orf45
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for C11orf45
-
Santa Cruz Biotechnology (SCBT) CRISPR for C11orf45
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for C11orf45
- Browse OriGene Inhibitory RNA Products For C11orf45
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C11orf45
Clone products for research
- Applied Biological Materials (abm): Clones for C11orf45 - Starting at $45 >
- * C11orf45 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for C11orf45
Relevant External Links for C11orf45 Gene
- GeneLoc Exon Structure for
- C11orf45
Expression for C11orf45 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for C11orf45
SOURCE GeneReport for Unigene cluster for C11orf45 Gene:
Hs.689860Evidence on tissue expression from TISSUES for C11orf45 Gene
- Lung(4.1)
Primer products for research
-
OriGene qPCR primer pairs for C11orf45
Gene Expression Assays for research
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for C11orf45 Gene
Orthologs for C11orf45 Gene
This gene was present in the common ancestor of human and chimp.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | C11H11orf45 30 |
|
||
| C11orf45 31 |
|
OneToOne |
- Species where no ortholog for C11orf45 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- Cow (Bos Taurus)
- Dog (Canis familiaris)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Mouse (Mus musculus)
- Oppossum (Monodelphis domestica)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rat (Rattus norvegicus)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
- Zebrafish (Danio rerio)
Paralogs for C11orf45 Gene
No data available for Paralogs for C11orf45 Gene
Variants for C11orf45 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for C11orf45 Gene
| SNP ID | Clinical significance and condition | Chr 11 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs78838391 | Benign: not provided | 128,902,706(-) |
T/C NM_000890.5(KCNJ5):c.-10-8558T>C |
NON_CODING_TRANSCRIPT_VARIANT,INTRON |
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
Residual Variation Intolerance Score:
73.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.26;
25.18% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for C11orf45 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- C11orf45
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C11orf45 Gene
Disorders for C11orf45 Gene
Additional Disease Information for C11orf45
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No disorders were found for C11orf45 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C11orf45 Gene
Publications for C11orf45 Gene
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
- A reference map of the human binary protein interactome. (PMID: 32296183) Luck K … Calderwood MA (Nature 2020) 3
- Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) Oláh J … Ovádi J (The Journal of biological chemistry 2011) 3
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 4
ExternalLinks
Products for C11orf45 Gene
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for C11orf45
- Search Origene for MassSpec and Protein Over-expression Lysates for C11orf45
- Origene Custom Protein Services for C11orf45
- Origene shrna, sirna, and RNAi products in human, mouse, rat for C11orf45
- Browse OriGene Inhibitory RNA Products For C11orf45
- OriGene qPCR primer pairs for C11orf45
- OriGene CRISPR knockouts for C11orf45
- OriGene ORF clones in human for C11orf45
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For C11orf45
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for C11orf45
- Novus Biologicals proteins and lysates for C11orf45
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Invitrogen Antibodies for C11orf45 (AFLGC-C11orf45)
- antibodies-online: Show 6 available C11ORF45 Antibodies ranked by validation data
- antibodies-online: Search results for available C11ORF45 related products ranked by validation data
- antibodies-online: Search results for available C11ORF45 related products ranked by validation data
- Horizon Cell Lines for C11orf45
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for C11orf45
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for C11orf45
- Search GeneCopoeia for miRNA 3'UTR Target clone products for C11orf45
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C11orf45
Sources for C11orf45 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Mar-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) MedlinePlus Genetics
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNAcentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Open Targets Platform
- (175) 5SRRNADB
- (176) snoDB
- (177) MirGeneDB