Aliases for C11orf16 Gene

Aliases for C11orf16 Gene

  • Chromosome 11 Open Reading Frame 16 2 3 5
  • Uncharacterized Protein C11orf16 3 4
  • C11orf16 5

External Ids for C11orf16 Gene

Previous GeneCards Identifiers for C11orf16 Gene

  • GC11P009967
  • GC11M009632
  • GC11M008980
  • GC11M008905
  • GC11M008898
  • GC11M008611
  • GC11M008941

Summaries for C11orf16 Gene

GeneCards Summary for C11orf16 Gene

C11orf16 (Chromosome 11 Open Reading Frame 16) is a Protein Coding gene. Diseases associated with C11orf16 include Adenofibroma.

Gene Wiki entry for C11orf16 Gene

Additional gene information for C11orf16 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for C11orf16 Gene

Genomics for C11orf16 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for C11orf16 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around C11orf16 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for C11orf16

Top Transcription factor binding sites by QIAGEN in the C11orf16 gene promoter:
  • AML1a
  • AP-1
  • AP-4
  • ATF-2
  • c-Jun
  • COMP1
  • ER-alpha
  • NRSF form 2
  • RORalpha1

Genomic Locations for C11orf16 Gene

Genomic Locations for C11orf16 Gene
12,931 bases
Minus strand
12,931 bases
Minus strand

Genomic View for C11orf16 Gene

Genes around C11orf16 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C11orf16 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C11orf16 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C11orf16 Gene

Proteins for C11orf16 Gene

  • Protein details for C11orf16 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C11orf16
    Protein Accession:
    Secondary Accessions:
    • Q53FB2
    • Q8N6Y9

    Protein attributes for C11orf16 Gene

    467 amino acids
    Molecular mass:
    51609 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C11orf16 Gene


neXtProt entry for C11orf16 Gene

Post-translational modifications for C11orf16 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C11orf16 Gene

No data available for DME Specific Peptides for C11orf16 Gene

Domains & Families for C11orf16 Gene

Gene Families for C11orf16 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for C11orf16 Gene

genes like me logo Genes that share domains with C11orf16: view

No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for C11orf16 Gene

Function for C11orf16 Gene

Phenotypes From GWAS Catalog for C11orf16 Gene

genes like me logo Genes that share phenotypes with C11orf16: view

Animal Model Products

CRISPR Products

miRNA for C11orf16 Gene

miRTarBase miRNAs that target C11orf16

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C11orf16

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C11orf16 Gene

Localization for C11orf16 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C11orf16 gene
Compartment Confidence
peroxisome 1
nucleus 1
cytosol 1
extracellular 0
mitochondrion 0

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for C11orf16 Gene

Pathways & Interactions for C11orf16 Gene

PathCards logo

SuperPathways for C11orf16 Gene

No Data Available

Interacting Proteins for C11orf16 Gene

STRING Interaction Network Preview (showing top 1 STRING interactants - click image to see details)
STRING Interaction Network
Selected Interacting proteins: Q9NQ32-CK016_HUMAN ENSP00000318999 for C11orf16 Gene via MINT STRING IID

Gene Ontology (GO) - Biological Process for C11orf16 Gene


No data available for Pathways by source and SIGNOR curated interactions for C11orf16 Gene

Drugs & Compounds for C11orf16 Gene

No Compound Related Data Available

Transcripts for C11orf16 Gene

mRNA/cDNA for C11orf16 Gene

5 NCBI additional mRNA sequence :
6 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C11orf16

Alternative Splicing Database (ASD) splice patterns (SP) for C11orf16 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b · 3c ^ 4a · 4b · 4c ^ 5a · 5b ^ 6 ^ 7 ^ 8
SP1: - - - -
SP2: - - - - -
SP3: - -
SP4: -
SP5: - -

Relevant External Links for C11orf16 Gene

GeneLoc Exon Structure for

Expression for C11orf16 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for C11orf16 Gene

mRNA differential expression in normal tissues according to GTEx for C11orf16 Gene

This gene is overexpressed in Fallopian Tube (x11.0), Cervix - Endocervix (x8.5), Testis (x8.0), and Lung (x6.7).

Protein differential expression in normal tissues from HIPED for C11orf16 Gene

This gene is overexpressed in Pancreatic juice (54.3) and Adipocyte (14.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C11orf16 Gene

Protein tissue co-expression partners for C11orf16 Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for C11orf16

SOURCE GeneReport for Unigene cluster for C11orf16 Gene:

genes like me logo Genes that share expression patterns with C11orf16: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C11orf16 Gene

Orthologs for C11orf16 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C11orf16 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C11H11orf16 30
  • 98.5 (n)
C11orf16 31
  • 97 (a)
(Bos Taurus)
Mammalia C15H11orf16 30
  • 79.18 (n)
C11ORF16 31
  • 65 (a)
(Canis familiaris)
Mammalia C21H11orf16 30
  • 77.9 (n)
C11orf16 31
  • 60 (a)
(Rattus norvegicus)
Mammalia LOC499240 30
  • 74.49 (n)
(Mus musculus)
Mammalia BC051019 30 17 31
  • 73.37 (n)
(Monodelphis domestica)
Mammalia C11orf16 31
  • 45 (a)
(Gallus gallus)
Aves C11ORF16 30
  • 51.51 (n)
C11orf16 31
  • 34 (a)
(Anolis carolinensis)
Reptilia C11orf16 31
  • 56 (a)
Species where no ortholog for C11orf16 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for C11orf16 Gene

Gene Tree for C11orf16 (if available)
Gene Tree for C11orf16 (if available)

Paralogs for C11orf16 Gene

No data available for Paralogs for C11orf16 Gene

Variants for C11orf16 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for C11orf16 Gene

SNP ID Clinical significance and condition Chr 11 pos Variation AA Info Type
rs11042127 - p.Val210Leu
rs2568076 - p.Pro144Leu

Additional dbSNP identifiers (rs#s) for C11orf16 Gene

Structural Variations from Database of Genomic Variants (DGV) for C11orf16 Gene

Variant ID Type Subtype PubMed ID
esv2759803 CNV gain 17122850
nsv435923 CNV deletion 17901297
nsv499766 OTHER inversion 21111241
nsv7215 OTHER inversion 18451855
nsv832062 CNV loss 17160897

Variation tolerance for C11orf16 Gene

Residual Variation Intolerance Score: 76.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 9.11; 87.71% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for C11orf16 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C11orf16 Gene

Disorders for C11orf16 Gene

MalaCards: The human disease database

(1) MalaCards diseases for C11orf16 Gene - From: DISEASES

Disorder Aliases PubMed IDs
- elite association - COSMIC cancer census association via MalaCards
genes like me logo Genes that share disorders with C11orf16: view

No data available for UniProtKB/Swiss-Prot and Genatlas for C11orf16 Gene

Publications for C11orf16 Gene

  1. Comparative genomic sequencing reveals a strikingly similar architecture of a conserved syntenic region on human chromosome 11p15.3 (including gene ST5) and mouse chromosome 7. (PMID: 11528127) Amid C … Schmidt ER (Cytogenetics and cell genetics 2001) 2 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
  3. A reference map of the human binary protein interactome. (PMID: 32296183) Luck K … Calderwood MA (Nature 2020) 3
  4. Gsk3β and Tomm20 are substrates of the SCFFbxo7/PARK15 ubiquitin ligase associated with Parkinson's disease. (PMID: 27503909) Teixeira FR … Laman H (The Biochemical journal 2016) 3
  5. A Y2H-seq approach defines the human protein methyltransferase interactome. (PMID: 23455924) Weimann M … Stelzl U (Nature methods 2013) 3

Products for C11orf16 Gene

  • Biorbyt antibodies for C11orf16

Sources for C11orf16 Gene