Aliases for C11orf45 Gene

Subcategory (RNA class) for C11orf45 Gene


Number of RNA Genes sources:

2 / 17

Aliases for C11orf45 Gene

  • Chromosome 11 Open Reading Frame 45 2 3 5
  • Putative Uncharacterized Protein C11orf45 3 4
  • Lnc-C11orf45-1 165
  • HSALNG0088130 164
  • C11orf45 5
  • MGC35558 2
  • FLJ43646 2

External Ids for C11orf45 Gene

Previous GeneCards Identifiers for C11orf45 Gene

  • GC11M128275
  • GC11M128769
  • GC11M124719

Summaries for C11orf45 Gene

GeneCards Summary for C11orf45 Gene

C11orf45 (Chromosome 11 Open Reading Frame 45) is an RNA Gene, and is affiliated with the lncRNA class.

Additional gene information for C11orf45 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for C11orf45 Gene

Genomics for C11orf45 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for C11orf45 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11J128905 Promoter/Enhancer 1.9 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas 607.7 +4.7 4690 3.7 CTCF FOXA1 ZIC2 PATZ1 EZH2 ZNF341 ZBTB44 KLF9 SP2 DPF2 C11orf45 TP53AIP1 KCNJ5 MN309310
GH11J128907 Promoter/Enhancer 1.2 EPDnew Ensembl ENCODE 617.1 +0.7 659 1.7 JUND CEBPB EZH2 JUN MAX EP300 FOSL2 RCOR1 FOS CHD2 C11orf45 MN309310 KCNJ5 TP53AIP1
GH11J128860 Enhancer 0.5 Ensembl ENCODE 28.5 +48.3 48338 1.4 CTCF ZFX C11orf45 KCNJ5 KCNJ1 LOC107984409 lnc-C11orf45-3-002 FLI1
GH11J128890 Promoter/Enhancer 1.8 EPDnew Ensembl ENCODE CraniofacialAtlas 6.7 +16.5 16523 5.6 PRDM10 REST KDM1A PRDM1 ZIC2 ZSCAN4 SP1 EZH2 ZNF600 ZNF341 KCNJ5 lnc-C11orf45-2 TP53AIP1 C11orf45
GH11J128936 Enhancer 0.9 Ensembl ENCODE CraniofacialAtlas 12 -27.5 -27493 1.6 TEAD4 POLR2A SOX13 RFX3 RAD21 YY1 ATF2 RFX1 TAF1 SP1 KCNJ5 C11orf45 ARHGAP32 RF00017-1062 TP53AIP1 lnc-ARHGAP32-3
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around C11orf45 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for C11orf45

Top Transcription factor binding sites by QIAGEN in the C11orf45 gene promoter:
  • E47
  • GATA-2
  • HOXA5
  • Nkx2-5
  • SRY
  • STAT1
  • STAT1beta
  • STAT2
  • STAT3
  • STAT4

Genomic Locations for C11orf45 Gene

Genomic Locations for C11orf45 Gene
9,956 bases
Minus strand
6,471 bases
Minus strand

Genomic View for C11orf45 Gene

Genes around C11orf45 on UCSC Golden Path with GeneCards custom track
C11orf45 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
C11orf45 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C11orf45 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C11orf45 Gene

Proteins for C11orf45 Gene

  • Protein details for C11orf45 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Putative uncharacterized protein C11orf45
    Protein Accession:
    Secondary Accessions:
    • B2RAD0

    Protein attributes for C11orf45 Gene

    145 amino acids
    Molecular mass:
    15559 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C11orf45 Gene

Post-translational modifications for C11orf45 Gene

  • Glycosylation at Asn98
  • Modification sites at PhosphoSitePlus

Other Protein References for C11orf45 Gene

No data available for DME Specific Peptides for C11orf45 Gene

Domains & Families for C11orf45 Gene

Gene Families for C11orf45 Gene

Human Protein Atlas (HPA):
  • Predicted secreted proteins

Protein Domains for C11orf45 Gene

genes like me logo Genes that share domains with C11orf45: view

No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for C11orf45 Gene

Function for C11orf45 Gene

Phenotypes From GWAS Catalog for C11orf45 Gene

genes like me logo Genes that share phenotypes with C11orf45: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C11orf45

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C11orf45 Gene

Localization for C11orf45 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C11orf45 Gene


Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C11orf45 gene
Compartment Confidence
extracellular 4
cytosol 2
mitochondrion 1
nucleus 0

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for C11orf45 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
genes like me logo Genes that share ontologies with C11orf45: view

Pathways & Interactions for C11orf45 Gene

PathCards logo

SuperPathways for C11orf45 Gene

No Data Available

Interacting Proteins for C11orf45 Gene

Gene Ontology (GO) - Biological Process for C11orf45 Gene


No data available for Pathways by source and SIGNOR curated interactions for C11orf45 Gene

Drugs & Compounds for C11orf45 Gene

No Compound Related Data Available

Transcripts for C11orf45 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for C11orf45 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS0000EF3149_9606 lncRNA 3624 1

Ensembl: ENST00000669709 (view in UCSC) ,

URS0000EF39E2_9606 lncRNA 609 1

Ensembl: ENST00000524878 (view in UCSC) ,

URS00008B6806_9606 lncRNA 515 2

LncBook: HSALNT0183277,

LNCipedia: lnc-C11orf45-1:2,

URS00008B2387_9606 lncRNA 3558 1

LNCipedia: lnc-C11orf45-1:1,

C11orf45 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for C11orf45 Gene

5 NCBI additional mRNA sequence :
3 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C11orf45

Alternative Splicing Database (ASD) splice patterns (SP) for C11orf45 Gene

No ASD Table

Relevant External Links for C11orf45 Gene

GeneLoc Exon Structure for

Expression for C11orf45 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for C11orf45 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for C11orf45

SOURCE GeneReport for Unigene cluster for C11orf45 Gene:


Evidence on tissue expression from TISSUES for C11orf45 Gene

  • Lung(4.1)
genes like me logo Genes that share expression patterns with C11orf45: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for C11orf45 Gene

Orthologs for C11orf45 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for C11orf45 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C11H11orf45 30
  • 99.31 (n)
C11orf45 31
  • 98 (a)
Species where no ortholog for C11orf45 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Cow (Bos Taurus)
  • Dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Mouse (Mus musculus)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for C11orf45 Gene

Gene Tree for C11orf45 (if available)
Gene Tree for C11orf45 (if available)

Paralogs for C11orf45 Gene

No data available for Paralogs for C11orf45 Gene

Variants for C11orf45 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for C11orf45 Gene

SNP ID Clinical significance and condition Chr 11 pos Variation AA Info Type

Additional dbSNP identifiers (rs#s) for C11orf45 Gene

Structural Variations from Database of Genomic Variants (DGV) for C11orf45 Gene

Variant ID Type Subtype PubMed ID
nsv468892 CNV loss 19166990
nsv556563 CNV loss 21841781

Variation tolerance for C11orf45 Gene

Residual Variation Intolerance Score: 73.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.26; 25.18% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for C11orf45 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C11orf45 Gene

Disorders for C11orf45 Gene

No disorders were found for C11orf45 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C11orf45 Gene

Publications for C11orf45 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
  2. A reference map of the human binary protein interactome. (PMID: 32296183) Luck K … Calderwood MA (Nature 2020) 3
  3. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) Oláh J … Ovádi J (The Journal of biological chemistry 2011) 3
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 4

Products for C11orf45 Gene

Sources for C11orf45 Gene