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Aliases for C10orf95 Gene

Aliases for C10orf95 Gene

  • Chromosome 10 Open Reading Frame 95 2 3 5
  • Uncharacterized Protein C10orf95 3

External Ids for C10orf95 Gene

Previous GeneCards Identifiers for C10orf95 Gene

  • GC10M103875
  • GC10M104199
  • GC10M097843

Summaries for C10orf95 Gene

GeneCards Summary for C10orf95 Gene

C10orf95 (Chromosome 10 Open Reading Frame 95) is a Protein Coding gene.

Additional gene information for C10orf95 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C10orf95 Gene

Genomics for C10orf95 Gene

GeneHancer (GH) Regulatory Elements for C10orf95 Gene

Promoters and enhancers for C10orf95 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10J102449 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 658.6 -1.6 -1637 8 PKNOX1 FOXA2 ARNT ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF766 C10orf95 RPARP-AS1 PPRC1 PCGF6 PDCD11 GBF1 MFSD13A SFXN2 CYP17A1-AS1 CUEDC2
GH10J102393 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 11.2 +55.8 55767 4.7 HDGF PKNOX1 SMAD1 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF213 E2F8 NFKB2 PPRC1 GBF1 SFXN2 C10orf95 MFSD13A ELOVL3 TAF5 PITX3 RPARP-AS1
GH10J102501 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 11.3 -51.8 -51846 4.6 HDGF PKNOX1 CLOCK FOXA2 ARNT ARID4B SIN3A DMAP1 ZNF2 ZBTB7B ACTR1A SUFU MFSD13A PDCD11 TAF5 PPRC1 PCGF6 RNU6-43P C10orf95 PSD
GH10J102595 Enhancer 1.7 FANTOM5 Ensembl ENCODE dbSUPER 10.6 -149.1 -149128 11.2 FOXA2 MLX ARID4B DMAP1 ZNF2 YY1 ZNF766 ZNF143 FOS SP5 MFSD13A SFXN2 ACTR1A SUFU C10orf95 PSD FBXL15 CUEDC2 MIR146B ARL3
GH10J102578 Enhancer 1.1 Ensembl ENCODE dbSUPER 10.8 -128.5 -128509 2.3 ZBTB21 CEBPG ZIC2 ZNF335 ZNF121 ZFHX2 ZNF316 VEZF1 SCRT2 MAFK MFSD13A ACTR1A SUFU C10orf95 NFKB2 AS3MT RPL23AP58 GC10P102592 GC10M102383 GC10M102382
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around C10orf95 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the C10orf95 gene promoter:
  • NRSF form 1
  • NRSF form 2
  • c-Jun
  • MZF-1
  • AP-1
  • c-Fos
  • CBF(2)
  • CBF-A
  • CBF-B
  • CBF-C

Genomic Locations for C10orf95 Gene

Genomic Locations for C10orf95 Gene
chr10:102,449,837-102,451,543
(GRCh38/hg38)
Size:
1,707 bases
Orientation:
Minus strand
chr10:104,209,594-104,211,300
(GRCh37/hg19)
Size:
1,707 bases
Orientation:
Minus strand

Genomic View for C10orf95 Gene

Genes around C10orf95 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C10orf95 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C10orf95 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C10orf95 Gene

Proteins for C10orf95 Gene

  • Protein details for C10orf95 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H7T3-CJ095_HUMAN
    Recommended name:
    Uncharacterized protein C10orf95
    Protein Accession:
    Q9H7T3
    Secondary Accessions:
    • A0AVQ7

    Protein attributes for C10orf95 Gene

    Size:
    257 amino acids
    Molecular mass:
    26270 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C10orf95 Gene

Post-translational modifications for C10orf95 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C10orf95 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C10orf95 Gene

Domains & Families for C10orf95 Gene

Gene Families for C10orf95 Gene

Human Protein Atlas (HPA):
  • Predicted secreted proteins

Protein Domains for C10orf95 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C10orf95: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C10orf95 Gene

Function for C10orf95 Gene

Phenotypes From GWAS Catalog for C10orf95 Gene

Gene Ontology (GO) - Molecular Function for C10orf95 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 21572394
genes like me logo Genes that share ontologies with C10orf95: view
genes like me logo Genes that share phenotypes with C10orf95: view

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C10orf95 Gene

Localization for C10orf95 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C10orf95 gene
Compartment Confidence
nucleus 4
extracellular 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for C10orf95 Gene

Pathways & Interactions for C10orf95 Gene

SuperPathways for C10orf95 Gene

No Data Available

Interacting Proteins for C10orf95 Gene

Gene Ontology (GO) - Biological Process for C10orf95 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C10orf95 Gene

Drugs & Compounds for C10orf95 Gene

No Compound Related Data Available

Transcripts for C10orf95 Gene

mRNA/cDNA for C10orf95 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(24) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C10orf95 Gene

Chromosome 10 open reading frame 95:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for C10orf95 Gene

No ASD Table

Relevant External Links for C10orf95 Gene

GeneLoc Exon Structure for
C10orf95
ECgene alternative splicing isoforms for
C10orf95

Expression for C10orf95 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C10orf95 Gene

Protein differential expression in normal tissues from HIPED for C10orf95 Gene

This gene is overexpressed in Fetal gut (63.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C10orf95 Gene



Protein tissue co-expression partners for C10orf95 Gene

NURSA nuclear receptor signaling pathways regulating expression of C10orf95 Gene:

C10orf95

SOURCE GeneReport for Unigene cluster for C10orf95 Gene:

Hs.225084
genes like me logo Genes that share expression patterns with C10orf95: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C10orf95 Gene

Orthologs for C10orf95 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for C10orf95 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C10orf95 34
  • 97 (a)
OneToOne
Species where no ortholog for C10orf95 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C10orf95 Gene

ENSEMBL:
Gene Tree for C10orf95 (if available)
TreeFam:
Gene Tree for C10orf95 (if available)

Paralogs for C10orf95 Gene

No data available for Paralogs for C10orf95 Gene

Variants for C10orf95 Gene

Sequence variations from dbSNP and Humsavar for C10orf95 Gene

SNP ID Clin Chr 10 pos Variation AA Info Type
rs1000311109 -- 102,450,330(-) G/C 3_prime_UTR_variant
rs1001039711 -- 102,451,346(-) C/A/T intron_variant
rs1001606031 -- 102,450,249(-) C/G/T 3_prime_UTR_variant
rs1001645490 -- 102,449,948(-) T/C 3_prime_UTR_variant
rs1001824160 -- 102,449,474(-) C/G downstream_transcript_variant

Variation tolerance for C10orf95 Gene

Gene Damage Index Score: 8.28; 85.14% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for C10orf95 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C10orf95

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for C10orf95 Gene

Disorders for C10orf95 Gene

Additional Disease Information for C10orf95

No disorders were found for C10orf95 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C10orf95 Gene

Publications for C10orf95 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  2. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P … Rogers J (Nature 2004) 3 4 58
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  4. Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array. (PMID: 23535732) Eeles RA … Easton DF (Nature genetics 2013) 3 58
  5. Nogo-B receptor is necessary for cellular dolichol biosynthesis and protein N-glycosylation. (PMID: 21572394) Harrison KD … Sessa WC (The EMBO journal 2011) 3 58

Products for C10orf95 Gene

Sources for C10orf95 Gene

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