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Aliases for C10orf91 Gene

Subcategory (RNA class) for C10orf91 Gene

ncRNA

Quality Score for this RNA gene is

3

Aliases for C10orf91 Gene

  • Chromosome 10 Open Reading Frame 91 (Putative) 2 3
  • Chromosome 10 Open Reading Frame 91 2 5

External Ids for C10orf91 Gene

Previous GeneCards Identifiers for C10orf91 Gene

  • GC10P133694
  • GC10P134108
  • GC10P134257
  • GC10P127810

Summaries for C10orf91 Gene

GeneCards Summary for C10orf91 Gene

C10orf91 (Chromosome 10 Open Reading Frame 91 (Putative)) is an RNA Gene, and is affiliated with the ncRNA class.

Additional gene information for C10orf91 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C10orf91 Gene

Genomics for C10orf91 Gene

GeneHancer (GH) Regulatory Elements for C10orf91 Gene

Promoters and enhancers for C10orf91 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10I132442 Enhancer 0.4 Ensembl dbSUPER 550.8 -1.4 -1426 0.2 C10orf91 LOC105378568
GH10I132392 Promoter/Enhancer 2.8 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 19 -35.9 -35925 32.2 HDGF PKNOX1 CLOCK SMAD1 ARID4B NEUROD1 SIN3A YBX1 DMAP1 ZBTB7B PWWP2B TUBGCP2 ENSG00000235245 C10orf91 ZNF511 STK32C LOC105378568 PAOX PPP2R2D MTG1
GH10I132443 Enhancer 1.5 FANTOM5 ENCODE dbSUPER 12.9 +2.1 2095 5.4 HDGF ARID4B ZNF48 GLIS2 KLF7 RUNX3 DEK SP3 SP5 NCOA1 C10orf91 JAKMIP3 LOC105378569
GH10I132334 Promoter/Enhancer 1.5 Ensembl ENCODE 11.5 -108.1 -108071 3 HDGF PKNOX1 FEZF1 DMAP1 ZNF2 ZNF766 ZNF143 FOS SP3 NFYC LRRC27 STK32C C10orf91 LOC105378568 PWWP2B GC10P132333
GH10I132375 Enhancer 1 Ensembl ENCODE dbSUPER 11.3 -68.3 -68300 1.3 ZNF687 USF1 L3MBTL2 MAX ELF1 GABPA GABPB1 MBD1 ZBTB33 NR2F6 LOC105378568 STK32C PWWP2B C10orf91 GC10P132333 LRRC27
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around C10orf91 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the C10orf91 gene promoter:

Genomic Locations for C10orf91 Gene

Genomic Locations for C10orf91 Gene
chr10:132,444,327-132,449,408
(GRCh38/hg38)
Size:
5,082 bases
Orientation:
Plus strand
chr10:134,257,831-134,262,912
(GRCh37/hg19)

Genomic View for C10orf91 Gene

Genes around C10orf91 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C10orf91 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C10orf91 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C10orf91 Gene

Proteins for C10orf91 Gene

  • Protein details for C10orf91 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5T1B1-CJ091_HUMAN
    Recommended name:
    Uncharacterized protein C10orf91
    Protein Accession:
    Q5T1B1
    Secondary Accessions:
    • Q8N0T7

    Protein attributes for C10orf91 Gene

    Size:
    145 amino acids
    Molecular mass:
    15403 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C10orf91 Gene

Post-translational modifications for C10orf91 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C10orf91 Gene

REFSEQ proteins:

No data available for DME Specific Peptides for C10orf91 Gene

Domains & Families for C10orf91 Gene

Protein Domains for C10orf91 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C10orf91: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C10orf91 Gene

Function for C10orf91 Gene

Phenotypes From GWAS Catalog for C10orf91 Gene

Phenotypes for C10orf91 Gene

genes like me logo Genes that share phenotypes with C10orf91: view

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C10orf91 Gene

Localization for C10orf91 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C10orf91 gene
Compartment Confidence
nucleus 3
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for C10orf91 Gene

Pathways & Interactions for C10orf91 Gene

SuperPathways for C10orf91 Gene

No Data Available

Interacting Proteins for C10orf91 Gene

Gene Ontology (GO) - Biological Process for C10orf91 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C10orf91 Gene

Drugs & Compounds for C10orf91 Gene

No Compound Related Data Available

Transcripts for C10orf91 Gene

mRNA/cDNA for C10orf91 Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(4) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C10orf91 Gene

Chromosome 10 open reading frame 91:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for C10orf91 Gene

No ASD Table

Relevant External Links for C10orf91 Gene

GeneLoc Exon Structure for
C10orf91
ECgene alternative splicing isoforms for
C10orf91

Expression for C10orf91 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C10orf91 Gene

mRNA differential expression in normal tissues according to GTEx for C10orf91 Gene

This gene is overexpressed in Esophagus - Mucosa (x7.0), Bladder (x6.5), and Skin - Not Sun Exposed (Suprapubic) (x4.1).

NURSA nuclear receptor signaling pathways regulating expression of C10orf91 Gene:

C10orf91

SOURCE GeneReport for Unigene cluster for C10orf91 Gene:

Hs.375059
genes like me logo Genes that share expression patterns with C10orf91: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C10orf91 Gene

Orthologs for C10orf91 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for C10orf91 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C10orf91 34
  • 95 (a)
OneToOne
Species where no ortholog for C10orf91 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C10orf91 Gene

ENSEMBL:
Gene Tree for C10orf91 (if available)
TreeFam:
Gene Tree for C10orf91 (if available)

Paralogs for C10orf91 Gene

No data available for Paralogs for C10orf91 Gene

Variants for C10orf91 Gene

Sequence variations from dbSNP and Humsavar for C10orf91 Gene

SNP ID Clin Chr 10 pos Variation AA Info Type
rs1000339227 -- 132,446,210(+) G/C intron_variant
rs1000367801 -- 132,446,588(+) C/T intron_variant
rs1000413187 -- 132,444,133(+) T/C upstream_transcript_variant
rs1001083251 -- 132,444,940(+) C/T upstream_transcript_variant
rs1001353631 -- 132,445,584(+) C/T intron_variant

Structural Variations from Database of Genomic Variants (DGV) for C10orf91 Gene

Variant ID Type Subtype PubMed ID
dgv121n27 CNV loss 19166990
dgv1458n54 CNV loss 21841781
esv2759791 CNV loss 17122850
esv3624986 CNV gain 21293372
nsv1054934 CNV gain 25217958
nsv1143659 CNV deletion 24896259
nsv470976 CNV loss 18288195
nsv552518 CNV loss 21841781
nsv832031 CNV loss 17160897
nsv951890 CNV deletion 24416366

Variation tolerance for C10orf91 Gene

Residual Variation Intolerance Score: 51.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.65; 31.58% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for C10orf91 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C10orf91

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C10orf91 Gene

Disorders for C10orf91 Gene

Additional Disease Information for C10orf91

No disorders were found for C10orf91 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C10orf91 Gene

Publications for C10orf91 Gene

  1. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P … Rogers J (Nature 2004) 3 4 58
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 58
  4. Genome-wide association study of chronic periodontitis in a general German population. (PMID: 24024966) Teumer A … Kocher T (Journal of clinical periodontology 2013) 3 58
  5. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P … Vidal M (Genomics 2007) 3 58

Products for C10orf91 Gene

Sources for C10orf91 Gene

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