Aliases for C10orf120 Gene
Aliases for C10orf120 Gene
External Ids for C10orf120 Gene
- HGNC: 25707
- Entrez Gene: 399814
- Ensembl: ENSG00000183559
- UniProtKB: Q5SQS8
Previous GeneCards Identifiers for C10orf120 Gene
- GC10M123998
- GC10M124447
- GC10M118075
Summaries for C10orf120 Gene
GeneCards Summary for C10orf120 Gene
C10orf120 (Chromosome 10 Open Reading Frame 120) is a Protein Coding gene.
Additional gene information for C10orf120 Gene
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C10orf120 Gene
Genomics for C10orf120 Gene
GeneHancer (GH) Regulatory Elements for C10orf120 Gene
Promoters and enhancers for C10orf120 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH10J122699 | Promoter | 0.5 | EPDnew | 650.7 | 0.0 | -44 | 0.1 | C10orf120 DMBT1P1 | ||
| GH10J121926 | Promoter/Enhancer | 2.3 | EPDnew Ensembl ENCODE | 9.8 | +771.0 | 771017 | 5.2 | HDGF PKNOX1 FOXA2 ARNT SIN3A DMAP1 ZNF2 YY1 POLR2B ZNF766 | ATE1-AS1 ATE1 GC10M121925 ENSG00000224250 RPL19P16 LINC01153 FAM24A NSMCE4A C10orf120 GC10P121933 | |
| GH10J122688 | Enhancer | 0.5 | ENCODE | 0.4 | +10.9 | 10858 | 0.9 | CTCF RXRA RAD21 NR2F2 | C10orf120 GC10M122639 | |
| GH10J122690 | Enhancer | 0.4 | ENCODE | 0.4 | +11.4 | 11399 | 0.1 | SP1 RXRA NR2F2 | C10orf120 GC10M122639 | |
| GH10J122648 | Enhancer | 0.6 | ENCODE | 0.2 | +50.9 | 50922 | 0.1 | SCRT1 CTCF ZNF654 SIN3A REST ZNF2 RAD21 XRCC5 SCRT2 SMC3 | GC10M122639 C10orf120 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)
GeneHancers around C10orf120 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the C10orf120 gene promoter:
-
- IRF-1
- AML1a
- aMEF-2
- MEF-2
- MEF-2A
- GATA-6
- AREB6
- c-Myb
- CUTL1
Regulatory Element Products
Genomic Locations for C10orf120 Gene
Genomic Locations for C10orf120 Gene
- chr10:122,697,709-122,699,822
- (GRCh38/hg38)
- Size:
- 2,114 bases
- Orientation:
- Minus strand
- chr10:124,457,225-124,459,338
- (GRCh37/hg19)
- Size:
- 2,114 bases
- Orientation:
- Minus strand
Genomic View for C10orf120 Gene
Genes around C10orf120 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 10q26.13 by Entrez Gene
- 10q26.13 by HGNC
- 10q26.13 by Ensembl
C10orf120 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for C10orf120 Gene
Proteins for C10orf120 Gene
-
Protein details for C10orf120 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q5SQS8-CJ120_HUMAN
- Recommended name:
- Uncharacterized protein C10orf120
- Protein Accession:
- Q5SQS8
- B2RU17
Protein attributes for C10orf120 Gene
- Size:
- 335 amino acids
- Molecular mass:
- 39268 Da
- Quaternary structure:
- No Data Available
Protein Expression for C10orf120 Gene
Post-translational modifications for C10orf120 Gene
Other Protein References for C10orf120 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for C10orf120
- Invitrogen Antibodies for C10orf120 (AFLGC-C10orf120)
- Search GeneTex for Antibodies for C10orf120
-
Boster Bio Antibodies for C10orf120
Protein Products
-
OriGene Purified Proteins for C10orf120
- Search Origene for MassSpec and Protein Over-expression Lysates for C10orf120
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- Search GeneTex for Proteins for C10orf120
Assay Products
No data available for DME Specific Peptides for C10orf120 Gene
Domains & Families for C10orf120 Gene
Gene Families for C10orf120 Gene
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for C10orf120 Gene
- ProtoNet:
Graphical View of Domain Structure for InterPro Entry
No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C10orf120 Gene
Function for C10orf120 Gene
Phenotypes From GWAS Catalog for C10orf120 Gene
Phenotypes for C10orf120 Gene
- MGI mutant phenotypes for C10orf120:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for C10orf120:
Animal Models for C10orf120 Gene
- MGI Knock Outs for C10orf120:
-
- 4933402N03Rik 4933402N03Rik<tm2a(KOMP)Wtsi>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for C10orf120
-
CRISPR Products
-
OriGene CRISPR knockouts for C10orf120
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- genomics-online: gRNA clones - Search results for 32 available C10ORF120 gene related products
- Overview of 32 available C10ORF120 gene related products
- Applied Biological Materials CRISPR for C10orf120
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for C10orf120
- GenScript: Design CRISPR guide RNA sequences for C10orf120
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for C10orf120
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- genomics-online: shRNA clones - Search results for 32 available C10ORF120 gene related products
- Overview of 32 available C10ORF120 gene related products
Clone Products
- Sino Biological Human cDNA Clone for C10orf120
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- Applied Biological Materials Clones for C10orf120
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for C10orf120
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for C10orf120 Gene
Localization for C10orf120 Gene
| Compartment | Confidence |
|---|---|
| nucleus | 4 |
| cytosol | 2 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000151 | ubiquitin ligase complex | IBA | -- |
| GO:0005634 | nucleus | IBA | -- |
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for C10orf120 Gene
Transcripts for C10orf120 Gene
mRNA/cDNA for C10orf120 Gene
- (1) REFSEQ mRNAs :
- (1) Additional mRNA sequences :
- (4) Selected AceView cDNA sequences:
- (2) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000432000 628 bps (uc057wnt.1)
- ENST00000329446 1064 bps (uc001lgn.3)
Unigene Clusters for C10orf120 Gene
- Chromosome 10 open reading frame 120:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for C10orf120
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for C10orf120
- genomics-online: gRNA clones - Search results for 32 available C10ORF120 gene related products
- Overview of 32 available C10ORF120 gene related products
- Applied Biological Materials CRISPR for C10orf120
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for C10orf120
- GenScript: Design CRISPR guide RNA sequences for C10orf120
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for C10orf120
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- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C10orf120
- genomics-online: shRNA clones - Search results for 32 available C10ORF120 gene related products
- Overview of 32 available C10ORF120 gene related products
Clone Products
- Sino Biological Human cDNA Clone for C10orf120
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- Applied Biological Materials Clones for C10orf120
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for C10orf120 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
mRNA differential expression in normal tissues according to GTEx for C10orf120 Gene
This gene is overexpressed in Testis (x51.9).
This gene is overexpressed in Fetal ovary (69.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C10orf120 Gene
NURSA nuclear receptor signaling pathways regulating expression of C10orf120 Gene:
C10orf120SOURCE GeneReport for Unigene cluster for C10orf120 Gene:
Hs.363649Primer Products
-
OriGene qPCR primer pairs for C10orf120
- genomics-online: primer clones - Search results for 32 available C10ORF120 gene related products
- Overview of 32 available C10ORF120 gene related products
Gene Expression Assay Products
No data available for mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C10orf120 Gene
Orthologs for C10orf120 Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | C10H10orf120 33 |
|
||
| C10orf120 34 |
|
OneToOne | |||
| dog (Canis familiaris) |
Mammalia | C28H10orf120 33 |
|
||
| C10orf120 34 |
|
OneToOne | |||
| cow (Bos Taurus) |
Mammalia | C26H10orf120 34 33 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | 4933402N03Rik 16 34 33 |
|
||
| rat (Rattus norvegicus) |
Mammalia | LOC499276 33 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | C10orf120 34 |
|
OneToOne |
- Species where no ortholog for C10orf120 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for C10orf120 Gene
No data available for Paralogs for C10orf120 Gene
Variants for C10orf120 Gene
| SNP ID | Clin | Chr 10 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1001974937 | -- | 122,697,229(-) | G/T | downstream_transcript_variant | |
| rs1002668025 | -- | 122,700,392(-) | T/C | upstream_transcript_variant | |
| rs1002768496 | -- | 122,697,423(-) | A/T | downstream_transcript_variant | |
| rs1002940989 | -- | 122,700,100(-) | C/T | upstream_transcript_variant | |
| rs1003367808 | -- | 122,698,703(-) | A/T | intron_variant |
Residual Variation Intolerance Score:
75.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.23;
62.24% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for C10orf120 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- C10orf120
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C10orf120 Gene
Disorders for C10orf120 Gene
Additional Disease Information for C10orf120
No disorders were found for C10orf120 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C10orf120 Gene
Publications for C10orf120 Gene
- The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P … Rogers J (Nature 2004) 3 4 58
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58
Products for C10orf120 Gene
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- Custom Antibody ServicesOriGene Antibodies for C10orf120
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Sources for C10orf120 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio
- (169) Biorbyt