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Aliases for C10orf120 Gene
Aliases for C10orf120 Gene
External Ids for C10orf120 Gene
- HGNC: 25707
- Entrez Gene: 399814
- Ensembl: ENSG00000183559
- UniProtKB: Q5SQS8
Previous GeneCards Identifiers for C10orf120 Gene
- GC10M123998
- GC10M124447
- GC10M118075
Summaries for C10orf120 Gene
GeneCards Summary for C10orf120 Gene
C10orf120 (Chromosome 10 Open Reading Frame 120) is a Protein Coding gene. An important paralog of this gene is GMCL1.
Additional gene information for C10orf120 Gene
- HGNC(25707)
- Entrez Gene(399814)
- Ensembl(ENSG00000183559)
- UniProtKB(Q5SQS8)
- Open Targets Platform(ENSG00000183559)
- Search for C10orf120 at DataMed
- Search for C10orf120 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for C10orf120 Gene
Genomics for C10orf120 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for C10orf120 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH10J122699 | Promoter | 0.3 | EPDnew | 600.7 | 0.0 | -20 | 0.1 | C10orf120 DMBT1L1 CUZD1 | ||
| GH10J122690 | Enhancer | 0.6 | Ensembl ENCODE | 0.4 | +10.8 | 10760 | 1.4 | CTCF SP1 NR2F2 RAD21 RXRA EZH2 | C10orf120 LOC112577516 | |
| GH10J122701 | Enhancer | 0.2 | Ensembl | 0.7 | -2.8 | -2755 | 0.4 | C10orf120 DMBT1L1 CUZD1 | ||
| GH10J122708 | Enhancer | 0.2 | Ensembl | 0.4 | -8.1 | -8055 | 0.6 | C10orf120 DMBT1L1 CUZD1 | ||
| GH10J122733 | Enhancer | 0.2 | Ensembl | 0.3 | -34.1 | -34055 | 1 | DMBT1L1 lnc-DMBT1-2 C10orf120 CUZD1 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around C10orf120 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for C10orf120
- Top Transcription factor binding sites by QIAGEN in the C10orf120 gene promoter:
-
- aMEF-2
- AML1a
- AREB6
- c-Myb
- CUTL1
- GATA-6
- IRF-1
- MEF-2
- MEF-2A
Genomic Locations for C10orf120 Gene
Genomic Locations for C10orf120 Gene
- chr10:122,697,709-122,699,846
- (GRCh38/hg38)
- Size:
- 2,138 bases
- Orientation:
- Minus strand
- chr10:124,457,225-124,459,338
- (GRCh37/hg19)
- Size:
- 2,114 bases
- Orientation:
- Minus strand
Genomic View for C10orf120 Gene
Genes around C10orf120 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 10q26.13 by HGNC
- 10q26.13 by Entrez Gene
- 10q26.13 by Ensembl
C10orf120 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for C10orf120 Gene
Proteins for C10orf120 Gene
-
Protein details for C10orf120 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q5SQS8-CJ120_HUMAN
- Recommended name:
- Uncharacterized protein C10orf120
- Protein Accession:
- Q5SQS8
- B2RU17
Protein attributes for C10orf120 Gene
- Size:
- 335 amino acids
- Molecular mass:
- 39268 Da
- Quaternary structure:
- No Data Available
Protein Expression for C10orf120 Gene
Post-translational modifications for C10orf120 Gene
Other Protein References for C10orf120 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for C10orf120
- Invitrogen Antibodies for C10orf120 (AFLGC-C10orf120)
- antibodies-online: Show 4 available C10ORF120 Antibodies ranked by validation data
Protein Products
-
OriGene Purified Proteins for C10orf120
- Search Origene for MassSpec and Protein Over-expression Lysates for C10orf120
- Origene Custom Protein Services for C10orf120
No data available for DME Specific Peptides for C10orf120 Gene
Domains & Families for C10orf120 Gene
Gene Families for C10orf120 Gene
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for C10orf120 Gene
Function for C10orf120 Gene
Phenotypes for C10orf120 Gene
- MGI mutant phenotypes for C10orf120:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for C10orf120:
Animal Models for C10orf120 Gene
- MGI Knock Outs for C10orf120:
-
- 4933402N03Rik 4933402N03Rik<tm2a(KOMP)Wtsi>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for C10orf120 - Select products 50% OFF >
- * C10orf120 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for C10orf120
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for C10orf120
-
Santa Cruz Biotechnology (SCBT) CRISPR for C10orf120
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for C10orf120
- Browse OriGene Inhibitory RNA Products For C10orf120
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C10orf120
Clone Products
- Applied Biological Materials (abm): Clones for C10orf120 - Select products 50% OFF >
- * C10orf120 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene ORF clones in human for C10orf120
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for C10orf120
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for C10orf120
Cell Line Products
-
Horizon Cell Lines for C10orf120
No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for C10orf120 Gene
Localization for C10orf120 Gene
| Compartment | Confidence |
|---|---|
| nucleus | 2 |
| cytosol | 2 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for C10orf120 Gene
Pathways & Interactions for C10orf120 Gene
Interacting Proteins for C10orf120 Gene
No data available for Pathways by source and SIGNOR curated interactions for C10orf120 Gene
Transcripts for C10orf120 Gene
mRNA/cDNA for C10orf120 Gene
- 1 REFSEQ mRNAs :
- 3 NCBI additional mRNA sequence :
- 2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000432000 628 nts (view in UCSC)
- ENST00000329446 1088 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for C10orf120 - Select products 50% OFF >
- * C10orf120 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for C10orf120
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for C10orf120
-
Santa Cruz Biotechnology (SCBT) CRISPR for C10orf120
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for C10orf120
- Browse OriGene Inhibitory RNA Products For C10orf120
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C10orf120
Clone Products
- Applied Biological Materials (abm): Clones for C10orf120 - Select products 50% OFF >
- * C10orf120 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene ORF clones in human for C10orf120
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for C10orf120
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for C10orf120
Relevant External Links for C10orf120 Gene
- GeneLoc Exon Structure for
- C10orf120
Expression for C10orf120 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
mRNA differential expression in normal tissues according to GTEx for C10orf120 Gene
This gene is overexpressed in Testis (x51.9).
This gene is overexpressed in Fetal ovary (69.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C10orf120 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for C10orf120
SOURCE GeneReport for Unigene cluster for C10orf120 Gene:
Hs.363649Primer Products
-
OriGene qPCR primer pairs for C10orf120
Gene Expression Assay Products
No data available for mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C10orf120 Gene
Orthologs for C10orf120 Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | C10H10orf120 30 |
|
||
| C10orf120 31 |
|
OneToOne | |||
| Dog (Canis familiaris) |
Mammalia | C28H10orf120 30 |
|
||
| C10orf120 31 |
|
OneToOne | |||
| Cow (Bos Taurus) |
Mammalia | C26H10orf120 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | 4933402N03Rik 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | LOC499276 30 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | C10orf120 31 |
|
OneToOne |
- Species where no ortholog for C10orf120 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
- Zebrafish (Danio rerio)
Paralogs for C10orf120 Gene
Variants for C10orf120 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for C10orf120 Gene
| SNP ID | Clinical significance and condition | Chr 10 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs2947594 | - | p.Ala269Thr | |||
| rs41448048 | - | p.Thr20Lys |
Residual Variation Intolerance Score:
75.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.23;
62.24% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for C10orf120 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- C10orf120
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C10orf120 Gene
Disorders for C10orf120 Gene
Additional Disease Information for C10orf120
No disorders were found for C10orf120 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C10orf120 Gene
Publications for C10orf120 Gene
- The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P … Rogers J (Nature 2004) 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
- A reference map of the human binary protein interactome. (PMID: 32296183) Luck K … Calderwood MA (Nature 2020) 3
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3
Products for C10orf120 Gene
- Custom Antibody ServicesOriGene Antibodies for C10orf120
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for C10orf120
- Search Origene for MassSpec and Protein Over-expression Lysates for C10orf120
- Origene Custom Protein Services for C10orf120
- Origene shrna, sirna, and RNAi products in human, mouse, rat for C10orf120
- Browse OriGene Inhibitory RNA Products For C10orf120
- OriGene qPCR primer pairs for C10orf120
- OriGene CRISPR knockouts for C10orf120
- OriGene ORF clones in human for C10orf120
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For C10orf120
- Sino Biological Human cDNA Clone for C10orf120
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Invitrogen Antibodies for C10orf120 (AFLGC-C10orf120)
- VectorBuilder Custom and pre-made DNA vectors for C10orf120 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for C10orf120 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for C10orf120 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for C10orf120 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for C10orf120
- antibodies-online: Show 4 available C10ORF120 Antibodies ranked by validation data
- antibodies-online: Search results for available C10ORF120 related products ranked by validation data
- antibodies-online: Search results for available C10ORF120 related products ranked by validation data
- Horizon Cell Lines for C10orf120
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for C10orf120
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for C10orf120
- Search GeneCopoeia for miRNA 3'UTR Target clone products for C10orf120
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C10orf120
Sources for C10orf120 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB