Aliases for C10orf62 Gene

Aliases for C10orf62 Gene

  • Chromosome 10 Open Reading Frame 62 2 3 5
  • Uncharacterized Protein C10orf62 3 4
  • BA548K23.1 2 3
  • C10orf62 5

External Ids for C10orf62 Gene

Previous GeneCards Identifiers for C10orf62 Gene

  • GC10U900455
  • GC10P099339
  • GC10P099349
  • GC10P092975

Summaries for C10orf62 Gene

GeneCards Summary for C10orf62 Gene

C10orf62 (Chromosome 10 Open Reading Frame 62) is a Protein Coding gene.

Additional gene information for C10orf62 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for C10orf62 Gene

Genomics for C10orf62 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for C10orf62 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10J097590 Enhancer 0.5 Ensembl 600.7 +1.5 1480 1.2 ZIC2 ZSCAN4 PKNOX1 NFIC ZNF335 NFIB ZNF664 MLLT1 C10orf62 piR-38051-048 HOGA1 MORN4 ENSG00000249967 L13712-002
GH10J097589 Enhancer 0.3 Ensembl 600.7 -0.3 -320 0.8 ZIC2 GLIS1 C10orf62 HOGA1 ENSG00000249967 L13712-002
GH10J097195 Promoter/Enhancer 1.5 FANTOM5 ENCODE CraniofacialAtlas dbSUPER 59.7 -393.2 -393210 1.6 CREB1 CTCF PRDM10 ZNF629 FOXA1 LARP7 ZNF143 ZIC2 PATZ1 RAD21 ENSG00000286683 LOC112268065 piR-57670 C10orf62 SLIT1 ARHGAP19 ARHGAP19-SLIT1
GH10J097639 Promoter/Enhancer 2.4 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 11 +51.8 51780 3.4 SP1 CREB1 GATAD2A PRDM10 ZNF512 RFX5 ZNF692 RCOR2 POLR2A BACH1 PI4K2A MORN4 HOGA1 ZFYVE27 MARVELD1 ANKRD2 AVPI1 C10orf62 ENSG00000249967 MMS19
GH10J097632 Promoter/Enhancer 2 EPDnew Ensembl ENCODE CraniofacialAtlas 11.3 +43.6 43603 1.8 SP1 HNRNPL CREB1 CTCF PRDM10 ZNF629 TFE3 RFX1 SIX5 KDM1A MORN4 ANKRD2 C10orf62 R3HCC1L ENSG00000249967 HOGA1 RF00017-766 L13712-002
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around C10orf62 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for C10orf62

Top Transcription factor binding sites by QIAGEN in the C10orf62 gene promoter:
  • AP-1
  • ARP-1
  • c-Fos
  • c-Jun
  • c-Myc
  • Ik-2
  • Max
  • MyoD
  • PPAR-gamma2

Genomic Locations for C10orf62 Gene

Genomic Locations for C10orf62 Gene
chr10:97,589,721-97,590,934
(GRCh38/hg38)
Size:
1,214 bases
Orientation:
Plus strand
chr10:99,349,450-99,350,691
(GRCh37/hg19)
Size:
1,242 bases
Orientation:
Plus strand

Genomic View for C10orf62 Gene

Genes around C10orf62 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C10orf62 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C10orf62 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C10orf62 Gene

Proteins for C10orf62 Gene

  • Protein details for C10orf62 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5T681-CJ062_HUMAN
    Recommended name:
    Uncharacterized protein C10orf62
    Protein Accession:
    Q5T681
    Secondary Accessions:
    • Q49A70
    • Q8N3Y6

    Protein attributes for C10orf62 Gene

    Size:
    223 amino acids
    Molecular mass:
    25128 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C10orf62 Gene

Post-translational modifications for C10orf62 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C10orf62 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C10orf62 Gene

Domains & Families for C10orf62 Gene

Gene Families for C10orf62 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for C10orf62 Gene

InterPro:
ProtoNet:
genes like me logo Genes that share domains with C10orf62: view

No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for C10orf62 Gene

Function for C10orf62 Gene

Phenotypes From GWAS Catalog for C10orf62 Gene

Gene Ontology (GO) - Molecular Function for C10orf62 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 16189514
genes like me logo Genes that share ontologies with C10orf62: view

Phenotypes for C10orf62 Gene

genes like me logo Genes that share phenotypes with C10orf62: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C10orf62

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C10orf62 Gene

Localization for C10orf62 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C10orf62 gene
Compartment Confidence
nucleus 3
mitochondrion 0

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for C10orf62 Gene

Pathways & Interactions for C10orf62 Gene

PathCards logo

SuperPathways for C10orf62 Gene

No Data Available

Gene Ontology (GO) - Biological Process for C10orf62 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C10orf62 Gene

Drugs & Compounds for C10orf62 Gene

No Compound Related Data Available

Transcripts for C10orf62 Gene

mRNA/cDNA for C10orf62 Gene

1 REFSEQ mRNAs :
3 NCBI additional mRNA sequence :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C10orf62

Alternative Splicing Database (ASD) splice patterns (SP) for C10orf62 Gene

No ASD Table

Relevant External Links for C10orf62 Gene

GeneLoc Exon Structure for
C10orf62

Expression for C10orf62 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for C10orf62 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

  • Testis (Reproductive System)

mRNA differential expression in normal tissues according to GTEx for C10orf62 Gene

This gene is overexpressed in Testis (x51.2).

Protein differential expression in normal tissues from HIPED for C10orf62 Gene

This gene is overexpressed in Testis (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C10orf62 Gene



Protein tissue co-expression partners for C10orf62 Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for C10orf62

SOURCE GeneReport for Unigene cluster for C10orf62 Gene:

Hs.662302
genes like me logo Genes that share expression patterns with C10orf62: view

Primer Products

No data available for mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C10orf62 Gene

Orthologs for C10orf62 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C10orf62 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia C10H10orf62 30
  • 98.95 (n)
Dog
(Canis familiaris)
Mammalia C28H10orf62 30
  • 78.84 (n)
C10orf62 31
  • 68 (a)
OneToOne
Cow
(Bos Taurus)
Mammalia C26H10orf62 30
  • 77.78 (n)
Rat
(Rattus norvegicus)
Mammalia MGC93861 30
  • 70.27 (n)
Mouse
(Mus musculus)
Mammalia 4933411K16Rik 30 17 31
  • 70.1 (n)
OneToOne
Oppossum
(Monodelphis domestica)
Mammalia C10orf62 31
  • 44 (a)
OneToOne
Platypus
(Ornithorhynchus anatinus)
Mammalia C10orf62 31
  • 41 (a)
OneToOne
Species where no ortholog for C10orf62 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for C10orf62 Gene

ENSEMBL:
Gene Tree for C10orf62 (if available)
TreeFam:
Gene Tree for C10orf62 (if available)

Paralogs for C10orf62 Gene

No data available for Paralogs for C10orf62 Gene

Variants for C10orf62 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for C10orf62 Gene

SNP ID Clinical significance and condition Chr 10 pos Variation AA Info Type
rs7093840 - p.Glu121Asp

Additional dbSNP identifiers (rs#s) for C10orf62 Gene

Structural Variations from Database of Genomic Variants (DGV) for C10orf62 Gene

Variant ID Type Subtype PubMed ID
nsv1047359 CNV gain 25217958
nsv1110852 OTHER inversion 24896259
nsv818782 CNV loss 17921354

Variation tolerance for C10orf62 Gene

Residual Variation Intolerance Score: 89.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.51; 82.26% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for C10orf62 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C10orf62

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C10orf62 Gene

Disorders for C10orf62 Gene

No disorders were found for C10orf62 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C10orf62 Gene

Publications for C10orf62 Gene

  1. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P … Rogers J (Nature 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
  3. A reference map of the human binary protein interactome. (PMID: 32296183) Luck K … Calderwood MA (Nature 2020) 3
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3
  5. An empirical framework for binary interactome mapping. (PMID: 19060904) Venkatesan K … Vidal M (Nature methods 2009) 3

Products for C10orf62 Gene

Sources for C10orf62 Gene