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Aliases for BTNL10 Gene

Aliases for BTNL10 Gene

  • Butyrophilin Like 10 2 3 5
  • Butyrophilin-Like Protein 10 3
  • Butyrophilin Related 1 3
  • Butyrophilin-Like 10 2
  • BUTR1 3
  • BTN4 3

External Ids for BTNL10 Gene

Previous GeneCards Identifiers for BTNL10 Gene

  • GC01M228697

Summaries for BTNL10 Gene

GeneCards Summary for BTNL10 Gene

BTNL10 (Butyrophilin Like 10) is a Protein Coding gene.

Additional gene information for BTNL10 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BTNL10 Gene

Genomics for BTNL10 Gene

GeneHancer (GH) Regulatory Elements for BTNL10 Gene

Promoters and enhancers for BTNL10 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J228513 Enhancer 1.2 ENCODE dbSUPER 661 +0.8 778 1.2 HDGF HNRNPUL1 SMAD1 ATF1 ARNT NCOA2 TCF12 ZNF766 GATA2 E2F8 BTNL10 CICP26 ENSG00000269890 HIST3H3 ENSG00000269934 OBSCN LOC105373124
GH01J228512 Enhancer 0.2 dbSUPER 650.7 +1.8 1848 0.2 BTNL10 HIST3H2A HIST3H2BB RPL23AP15 ENSG00000231563 TRIM11 LOC105373124
GH01J228514 Enhancer 0.2 dbSUPER 650.7 +1.6 1612 0.2 BTNL10 LOC105373124
GH01J228455 Promoter/Enhancer 1.8 Ensembl ENCODE dbSUPER 10.5 +56.1 56116 4.2 CLOCK FEZF1 YY1 ZNF213 E2F8 ZNF143 SP3 ZFP41 ZNF610 GLIS1 HIST3H2A GC01M228457 HIST3H2BB CICP26 C1orf35 ENSG00000269890 ZNF678 PRSS38 HIST3H3 LOC100421842
GH01J228840 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 10.9 -328.0 -328014 2.1 PKNOX1 ATF1 ZNF2 ZNF548 ATF7 FOS DEK REST TSHZ1 ZNF518A CICP26 ENSG00000269890 HMGN2P19 NUP133 TAF5L BTNL10 ABCB10 HIST3H3 ENSG00000271399 URB2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around BTNL10 on UCSC Golden Path with GeneCards custom track

Genomic Locations for BTNL10 Gene

Genomic Locations for BTNL10 Gene
chr1:228,508,027-228,514,017
(GRCh38/hg38)
Size:
5,991 bases
Orientation:
Minus strand
chr1:228,696,347-228,700,006
(GRCh37/hg19)
Size:
3,660 bases
Orientation:
Minus strand

Genomic View for BTNL10 Gene

Genes around BTNL10 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
BTNL10 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for BTNL10 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BTNL10 Gene

Proteins for BTNL10 Gene

  • Protein details for BTNL10 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A8MVZ5-BTNLA_HUMAN
    Recommended name:
    Butyrophilin-like protein 10
    Protein Accession:
    A8MVZ5

    Protein attributes for BTNL10 Gene

    Size:
    291 amino acids
    Molecular mass:
    32612 Da
    Quaternary structure:
    No Data Available

neXtProt entry for BTNL10 Gene

Post-translational modifications for BTNL10 Gene

  • Glycosylation at Asn59
  • Modification sites at PhosphoSitePlus

Other Protein References for BTNL10 Gene

No data available for DME Specific Peptides for BTNL10 Gene

Domains & Families for BTNL10 Gene

Gene Families for BTNL10 Gene

Protein Domains for BTNL10 Gene

Graphical View of Domain Structure for InterPro Entry

A8MVZ5

UniProtKB/Swiss-Prot:

BTNLA_HUMAN :
  • Belongs to the immunoglobulin superfamily. BTN/MOG family.
Family:
  • Belongs to the immunoglobulin superfamily. BTN/MOG family.
genes like me logo Genes that share domains with BTNL10: view

No data available for Suggested Antigen Peptide Sequences for BTNL10 Gene

Function for BTNL10 Gene

Phenotypes From GWAS Catalog for BTNL10 Gene

Gene Ontology (GO) - Molecular Function for BTNL10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005102 signaling receptor binding IBA --
genes like me logo Genes that share ontologies with BTNL10: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for BTNL10

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for BTNL10 Gene

Localization for BTNL10 Gene

Subcellular locations from UniProtKB/Swiss-Prot for BTNL10 Gene

Membrane; Single-pass type I membrane protein.

Gene Ontology (GO) - Cellular Components for BTNL10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0009897 external side of plasma membrane IBA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with BTNL10: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for BTNL10 Gene

Pathways & Interactions for BTNL10 Gene

SuperPathways for BTNL10 Gene

No Data Available

Interacting Proteins for BTNL10 Gene

Gene Ontology (GO) - Biological Process for BTNL10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001817 regulation of cytokine production IBA --
GO:0050776 regulation of immune response IBA --
GO:0050852 T cell receptor signaling pathway IBA --
genes like me logo Genes that share ontologies with BTNL10: view

No data available for Pathways by source and SIGNOR curated interactions for BTNL10 Gene

Drugs & Compounds for BTNL10 Gene

No Compound Related Data Available

Transcripts for BTNL10 Gene

mRNA/cDNA for BTNL10 Gene

(4) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for BTNL10

Alternative Splicing Database (ASD) splice patterns (SP) for BTNL10 Gene

No ASD Table

Relevant External Links for BTNL10 Gene

GeneLoc Exon Structure for
BTNL10
ECgene alternative splicing isoforms for
BTNL10

Expression for BTNL10 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for BTNL10 Gene

mRNA differential expression in normal tissues according to GTEx for BTNL10 Gene

This gene is overexpressed in Whole Blood (x15.7) and Testis (x4.2).

NURSA nuclear receptor signaling pathways regulating expression of BTNL10 Gene:

BTNL10
genes like me logo Genes that share expression patterns with BTNL10: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for BTNL10 Gene

Orthologs for BTNL10 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for BTNL10 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia BTNL10 33
  • 99.2 (n)
Species where no ortholog for BTNL10 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for BTNL10 Gene

ENSEMBL:
Gene Tree for BTNL10 (if available)
TreeFam:
Gene Tree for BTNL10 (if available)

Paralogs for BTNL10 Gene

(8) SIMAP similar genes for BTNL10 Gene using alignment to 1 proteins:

  • BTNLA_HUMAN
genes like me logo Genes that share paralogs with BTNL10: view

No data available for Paralogs for BTNL10 Gene

Variants for BTNL10 Gene

Sequence variations from dbSNP and Humsavar for BTNL10 Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1000085594 -- 228,511,666(-) G/T coding_sequence_variant, missense_variant, non_coding_transcript_variant
rs1000094621 -- 228,507,687(-) C/G downstream_transcript_variant
rs1000631564 -- 228,515,698(-) C/T upstream_transcript_variant
rs1001120194 -- 228,509,921(-) C/T downstream_transcript_variant, genic_downstream_transcript_variant, intron_variant
rs1002202834 -- 228,509,184(-) C/A genic_downstream_transcript_variant, intron_variant

Structural Variations from Database of Genomic Variants (DGV) for BTNL10 Gene

Variant ID Type Subtype PubMed ID
dgv841n54 CNV gain 21841781
esv32853 CNV gain 17666407
nsv1013500 CNV gain 25217958
nsv468305 CNV gain 19166990
nsv549296 CNV gain 21841781

Additional Variant Information for BTNL10 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
BTNL10

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for BTNL10 Gene

Disorders for BTNL10 Gene

Additional Disease Information for BTNL10

No disorders were found for BTNL10 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for BTNL10 Gene

Publications for BTNL10 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 4 58
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3

Products for BTNL10 Gene

Sources for BTNL10 Gene

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