Aliases for BTN2A2 Gene
External Ids for BTN2A2 Gene
Previous GeneCards Identifiers for BTN2A2 Gene
Butyrophilin is the major protein associated with fat droplets in the milk. This gene is a member of the BTN2 subfamily of genes, which encode proteins belonging to the butyrophilin protein family. The gene is located in a cluster on chromosome 6, consisting of seven genes belonging to the expanding B7/butyrophilin-like group, a subset of the immunoglobulin gene superfamily. The encoded protein is a type I receptor glycoprotein involved in lipid, fatty-acid and sterol metabolism. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
GeneCards Summary for BTN2A2 Gene
BTN2A2 (Butyrophilin Subfamily 2 Member A2) is a Protein Coding gene. Among its related pathways are T Cell Co-Signaling Pathway: Ligand-Receptor Interactions and Butyrophilin (BTN) family interactions. An important paralog of this gene is BTN2A1.
UniProtKB/Swiss-Prot Summary for BTN2A2 Gene
Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.