Aliases for BTG1 Gene
External Ids for BTG1 Gene
Previous GeneCards Identifiers for BTG1 Gene
This gene is a member of an anti-proliferative gene family that regulates cell growth and differentiation. Expression of this gene is highest in the G0/G1 phases of the cell cycle and downregulated when cells progressed through G1. The encoded protein interacts with several nuclear receptors, and functions as a coactivator of cell differentiation. This locus has been shown to be involved in a t(8;12)(q24;q22) chromosomal translocation in a case of B-cell chronic lymphocytic leukemia. [provided by RefSeq, Oct 2008]
GeneCards Summary for BTG1 Gene
BTG1 (BTG Anti-Proliferation Factor 1) is a Protein Coding gene. Diseases associated with BTG1 include Lymphocytic Leukemia. Among its related pathways are Cyclins and Cell Cycle Regulation and Deadenylation-dependent mRNA decay. Gene Ontology (GO) annotations related to this gene include enzyme binding and transcription coregulator activity. An important paralog of this gene is BTG2.
UniProtKB/Swiss-Prot Summary for BTG1 Gene