Aliases for BTG1 Gene
External Ids for BTG1 Gene
Previous GeneCards Identifiers for BTG1 Gene
This gene is a member of an anti-proliferative gene family that regulates cell growth and differentiation. Expression of this gene is highest in the G0/G1 phases of the cell cycle and downregulated when cells progressed through G1. The encoded protein interacts with several nuclear receptors, and functions as a coactivator of cell differentiation. This locus has been shown to be involved in a t(8;12)(q24;q22) chromosomal translocation in a case of B-cell chronic lymphocytic leukemia. [provided by RefSeq, Oct 2008]
GeneCards Summary for BTG1 Gene
BTG1 (BTG Anti-Proliferation Factor 1) is a Protein Coding gene. Diseases associated with BTG1 include Leukemia and Charcot-Marie-Tooth Disease. Among its related pathways are Diurnally Regulated Genes with Circadian Orthologs and Cyclins and Cell Cycle Regulation. Gene Ontology (GO) annotations related to this gene include enzyme binding and transcription coregulator activity. An important paralog of this gene is BTG2.
UniProtKB/Swiss-Prot Summary for BTG1 Gene