Aliases for BTBD17 Gene
Aliases for BTBD17 Gene
External Ids for BTBD17 Gene
- HGNC: 33758
- Entrez Gene: 388419
- Ensembl: ENSG00000204347
- UniProtKB: A6NE02
Previous GeneCards Identifiers for BTBD17 Gene
- GC17M069865
- GC17M072352
- GC17M067762
Summaries for BTBD17 Gene
GeneCards Summary for BTBD17 Gene
BTBD17 (BTB Domain Containing 17) is a Protein Coding gene. An important paralog of this gene is LGALS3BP.
Additional gene information for BTBD17 Gene
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BTBD17 Gene
Genomics for BTBD17 Gene
GeneHancer (GH) Regulatory Elements for BTBD17 Gene
Promoters and enhancers for BTBD17 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around BTBD17 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for BTBD17 Gene
Genomic Locations for BTBD17 Gene
- chr17:74,356,416-74,363,652
- (GRCh38/hg38)
- Size:
- 7,237 bases
- Orientation:
- Minus strand
- chr17:72,352,555-72,358,085
- (GRCh37/hg19)
Genomic View for BTBD17 Gene
Genes around BTBD17 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 17q25.1 by Ensembl
- 17q25.1 by Entrez Gene
- 17q25.1 by HGNC
BTBD17 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for BTBD17 Gene
Proteins for BTBD17 Gene
-
Protein details for BTBD17 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- A6NE02-BTBDH_HUMAN
- Recommended name:
- BTB/POZ domain-containing protein 17
- Protein Accession:
- A6NE02
Protein attributes for BTBD17 Gene
- Size:
- 478 amino acids
- Molecular mass:
- 52471 Da
- Quaternary structure:
- No Data Available
Protein Expression for BTBD17 Gene
Post-translational modifications for BTBD17 Gene
Other Protein References for BTBD17 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for BTBD17
- Novus Biologicals Antibodies for BTBD17
- Invitrogen Antibodies for BTBD17
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Protein Products
-
OriGene Purified Proteins for BTBD17
- Search Origene for MassSpec and Protein Over-expression Lysates for BTBD17
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Assay Products
No data available for DME Specific Peptides for BTBD17 Gene
Domains & Families for BTBD17 Gene
Gene Families for BTBD17 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted secreted proteins
Protein Domains for BTBD17 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for BTBD17 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for BTBD17 Gene
Function for BTBD17 Gene
Animal Model Products
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-
-
ViGene Biosciences lentiviral particle packaged cDNA for BTBD17 gene
-
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- Search ViGene Biosciences for BTBD17
CRISPR Products
-
OriGene CRISPR knockouts for BTBD17
- genomics-online: gRNA clones - Search results for 69 available BTBD17 gene related products
- Overview of 69 available BTBD17 gene related products
- Applied Biological Materials CRISPR for BTBD17
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for BTBD17
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miRNA for BTBD17 Gene
- miRTarBase miRNAs that target BTBD17
miRNA Products
- Search ViGene Biosciences for BTBD17
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for BTBD17
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- Overview of 69 available BTBD17 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for BTBD17 gene
Clone Products
- VectorBuilder custom plasmid, inducible vectors for BTBD17
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for BTBD17
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for BTBD17
-
ViGene Biosciences adenoviral particle packaged cDNA for BTBD17 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for BTBD17 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for BTBD17 gene
No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for BTBD17 Gene
Localization for BTBD17 Gene
Subcellular locations from UniProtKB/Swiss-Prot for BTBD17 Gene
- Secreted.
| Compartment | Confidence |
|---|---|
| plasma membrane | 4 |
| extracellular | 4 |
| mitochondrion | 3 |
| cytosol | 2 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | IEA | -- |
| GO:0005737 | colocalizes_with cytoplasm | ISS | -- |
| GO:0005886 | plasma membrane | ISS | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for BTBD17 Gene
Pathways & Interactions for BTBD17 Gene
No Data Available
Interacting Proteins for BTBD17 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0009615 | response to virus | ISS | -- |
| GO:0045071 | negative regulation of viral genome replication | ISS | -- |
No data available for Pathways by source and SIGNOR curated interactions for BTBD17 Gene
Transcripts for BTBD17 Gene
mRNA/cDNA for BTBD17 Gene
- (3) REFSEQ mRNAs :
- (0) Additional mRNA sequences :
- -
- (30) Selected AceView cDNA sequences:
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for BTBD17 Gene
- BTB (POZ) domain containing 17:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for BTBD17
- genomics-online: gRNA clones - Search results for 69 available BTBD17 gene related products
- Overview of 69 available BTBD17 gene related products
- Applied Biological Materials CRISPR for BTBD17
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for BTBD17
- GenScript: Design CRISPR guide RNA sequences for BTBD17
miRNA Products
- Search ViGene Biosciences for BTBD17
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for BTBD17
- Browse OriGene Inhibitory RNA Products For BTBD17
- genomics-online: shRNA clones - Search results for 69 available BTBD17 gene related products
- Overview of 69 available BTBD17 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for BTBD17 gene
Clone Products
- VectorBuilder custom plasmid, inducible vectors for BTBD17
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for BTBD17
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for BTBD17
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for BTBD17 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Brain (Nervous System)
-
Glial Cells
- Protoplasmic Astrocyte Cells Neocortex
- Eye (Sensory Organs)
mRNA differential expression in normal tissues according to GTEx for BTBD17 Gene
This gene is overexpressed in Brain - Cerebellum (x5.3), Brain - Putamen (basal ganglia) (x5.2), Brain - Amygdala (x4.9), Brain - Hypothalamus (x4.9), Brain - Nucleus accumbens (basal ganglia) (x4.4), and Brain - Caudate (basal ganglia) (x4.3).
This gene is overexpressed in Fetal Brain (61.3).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for BTBD17 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of BTBD17 Gene:
BTBD17SOURCE GeneReport for Unigene cluster for BTBD17 Gene:
Hs.211870Primer Products
-
OriGene qPCR primer pairs for BTBD17
- genomics-online: primer clones - Search results for 69 available BTBD17 gene related products
- Overview of 69 available BTBD17 gene related products
Gene Expression Assay Products
No data available for mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for BTBD17 Gene
Orthologs for BTBD17 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | BTBD17 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | BTBD17 33 34 |
|
||
| cow (Bos Taurus) |
Mammalia | BTBD17 33 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Btbd17 33 16 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Btbd17 33 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | BTBD17 34 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | BTBD17 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | BTBD17 33 34 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | BTBD17 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | btbd17 33 |
|
||
| Str.10709 33 |
|
||||
| zebrafish (Danio rerio) |
Actinopterygii | btbd17b 33 34 |
|
||
| btbd17a 34 |
|
OneToMany | |||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP000791 33 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | Tango10 33 34 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | W07A12.4 34 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToMany |
- Species where no ortholog for BTBD17 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for BTBD17 Gene
Variants for BTBD17 Gene
| SNP ID | Clin | Chr 17 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000344942 | -- | 74,358,373(-) | G/A | intron_variant | |
| rs1001394712 | -- | 74,357,712(-) | G/A/C | coding_sequence_variant, missense_variant, synonymous_variant | |
| rs1001659129 | -- | 74,362,955(-) | A/C | genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant | |
| rs1001711558 | -- | 74,362,525(-) | C/T | genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant | |
| rs1001992647 | -- | 74,364,042(-) | G/C | upstream_transcript_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv12e196 | CNV | duplication | 17116639 |
| dgv3282n100 | CNV | gain | 25217958 |
| dgv372n27 | CNV | gain | 19166990 |
| dgv5768n54 | CNV | gain | 21841781 |
| esv2751770 | CNV | gain | 17911159 |
| esv2761978 | CNV | gain | 21179565 |
| esv33995 | CNV | loss | 17666407 |
| esv3573820 | CNV | gain | 25503493 |
| esv3641230 | CNV | gain | 21293372 |
| esv3641237 | CNV | gain | 21293372 |
| nsv509673 | CNV | insertion | 20534489 |
| nsv517569 | CNV | gain+loss | 19592680 |
| nsv833538 | CNV | gain | 17160897 |
| nsv833539 | CNV | loss | 17160897 |
Gene Damage Index Score:
5.36;
70.90% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for BTBD17 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- BTBD17
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for BTBD17 Gene
Disorders for BTBD17 Gene
Additional Disease Information for BTBD17
No disorders were found for BTBD17 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for BTBD17 Gene
Publications for BTBD17 Gene
- DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PMID: 16625196) Zody MC … Nusbaum C (Nature 2006) 3 4 58
Products for BTBD17 Gene
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- Custom Antibody ServicesOriGene Antibodies for BTBD17
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- Cyagen custom Knockout/knockin (KOKI) mouse models for BTBD17
- VectorBuilder custom plasmid, inducible vectors for BTBD17
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for BTBD17
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for available BTBD17 related products ranked by validation data
- antibodies-online: Search results for available BTBD17 related products ranked by validation data
- antibodies-online: Search results for available BTBD17 related products ranked by validation data
- Search GeneTex for Antibodies for BTBD17
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- ViGene Biosciences adenoviral particle packaged cDNA for BTBD17 gene
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- genomics-online: cdna clones - Search results for 69 available BTBD17 gene related products
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- Overview of 69 available BTBD17 gene related products
Sources for BTBD17 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems