Aliases for BSG Gene
External Ids for BSG Gene
Previous HGNC Symbols for BSG Gene
Previous GeneCards Identifiers for BSG Gene
The protein encoded by this gene is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. The encoded protein is also a member of the immunoglobulin superfamily. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for BSG Gene
BSG (Basigin (Ok Blood Group)) is a Protein Coding gene. Diseases associated with BSG include Adult Brain Stem Glioma and Brain Stem Cancer. Among its related pathways are Pyruvate metabolism and Citric Acid (TCA) cycle and Syndecan-1-mediated signaling events. Gene Ontology (GO) annotations related to this gene include mannose binding. An important paralog of this gene is NPTN.
UniProtKB/Swiss-Prot for BSG Gene
Plays an important role in targeting the monocarboxylate transporters SLC16A1, SLC16A3, SLC16A8, SLC16A11 and SLC16A12 to the plasma membrane (PubMed:21778275). Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes.