Aliases for BSDC1 Gene

Aliases for BSDC1 Gene

  • BSD Domain Containing 1 2 3 5
  • BSD Domain-Containing Protein 1 3 4

External Ids for BSDC1 Gene

Previous GeneCards Identifiers for BSDC1 Gene

  • GC01M032500
  • GC01M032603
  • GC01M032831
  • GC01M030946
  • GC01M032833

Summaries for BSDC1 Gene

GeneCards Summary for BSDC1 Gene

BSDC1 (BSD Domain Containing 1) is a Protein Coding gene. An important paralog of this gene is SYAP1.

Additional gene information for BSDC1 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for BSDC1 Gene

Genomics for BSDC1 Gene

GeneHancer (GH) Regulatory Elements for BSDC1 Gene

Promoters and enhancers for BSDC1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around BSDC1 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for BSDC1

Top Transcription factor binding sites by QIAGEN in the BSDC1 gene promoter:
  • AP-1
  • c-Fos
  • c-Jun
  • Chx10
  • Egr-2
  • FOXC1
  • GATA-1
  • Pax-6
  • PPAR-alpha
  • Sp1

Genomic Locations for BSDC1 Gene

Genomic Locations for BSDC1 Gene
chr1:32,364,633-32,394,731
(GRCh38/hg38)
Size:
30,099 bases
Orientation:
Minus strand
chr1:32,830,704-32,860,332
(GRCh37/hg19)
Size:
29,629 bases
Orientation:
Minus strand

Genomic View for BSDC1 Gene

Genes around BSDC1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
BSDC1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for BSDC1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BSDC1 Gene

Proteins for BSDC1 Gene

  • Protein details for BSDC1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NW68-BSDC1_HUMAN
    Recommended name:
    BSD domain-containing protein 1
    Protein Accession:
    Q9NW68
    Secondary Accessions:
    • B4DMS7
    • B4DTI7
    • B4DTP7
    • B4E2X8
    • Q49AT8
    • Q68DY6
    • Q6IAA3
    • Q6MZK1
    • Q6UXS1
    • Q9HAL9

    Protein attributes for BSDC1 Gene

    Size:
    430 amino acids
    Molecular mass:
    47163 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for BSDC1 Gene

neXtProt entry for BSDC1 Gene

Post-translational modifications for BSDC1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for BSDC1 Gene

Domains & Families for BSDC1 Gene

Gene Families for BSDC1 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for BSDC1 Gene

Blocks:
  • BSD domain
InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for BSDC1 Gene

GenScript: Design optimal peptide antigens:
  • cDNA FLJ57704, moderately similar to Homo sapiens BSD domain containing 1 (BSDC1), mRNA (B4DE39_HUMAN)
  • cDNA FLJ58587, moderately similar to Homo sapiens BSD domain containing 1 (BSDC1), mRNA (B4DM89_HUMAN)
  • BSD domain-containing protein 1 (BSDC1_HUMAN)
genes like me logo Genes that share domains with BSDC1: view

No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for BSDC1 Gene

Function for BSDC1 Gene

Phenotypes From GWAS Catalog for BSDC1 Gene

Gene Ontology (GO) - Molecular Function for BSDC1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 30614533
genes like me logo Genes that share ontologies with BSDC1: view
genes like me logo Genes that share phenotypes with BSDC1: view

Animal Model Products

CRISPR Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for BSDC1 Gene

Localization for BSDC1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for BSDC1 gene
Compartment Confidence
golgi apparatus 3
plasma membrane 2
cytoskeleton 2
nucleus 2
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Golgi apparatus (4)
  • Plasma membrane (2)
See all subcellular structures

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for BSDC1 Gene

Pathways & Interactions for BSDC1 Gene

PathCards logo

SuperPathways for BSDC1 Gene

No Data Available

Interacting Proteins for BSDC1 Gene

;

Gene Ontology (GO) - Biological Process for BSDC1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for BSDC1 Gene

Drugs & Compounds for BSDC1 Gene

No Compound Related Data Available

Transcripts for BSDC1 Gene

mRNA/cDNA for BSDC1 Gene

5 REFSEQ mRNAs :
29 NCBI additional mRNA sequence :
16 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for BSDC1 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b · 3c ^ 4a · 4b · 4c · 4d ^ 5a · 5b · 5c ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9a · 9b ^ 10a · 10b · 10c · 10d ^ 11 ^ 12 ^
SP1: - - - -
SP2: - - - - -
SP3: - - - - -
SP4: - -
SP5: - - - - -
SP6: - -
SP7: - -
SP8: - - -
SP9: - - - - - - - - -
SP10: - - - - - - - - - - - - - - - - - - -
SP11: - - - - - -
SP12: -
SP13: -
SP14:

ExUns: 13a · 13b ^ 14a · 14b · 14c
SP1: -
SP2: -
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10: -
SP11:
SP12:
SP13:
SP14:

Relevant External Links for BSDC1 Gene

GeneLoc Exon Structure for
BSDC1

Expression for BSDC1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for BSDC1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for BSDC1 Gene

This gene is overexpressed in Testis (18.0) and Peripheral blood mononuclear cells (6.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for BSDC1 Gene



Protein tissue co-expression partners for BSDC1 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for BSDC1

SOURCE GeneReport for Unigene cluster for BSDC1 Gene:

Hs.353454

Evidence on tissue expression from TISSUES for BSDC1 Gene

  • Nervous system(4.9)
  • Eye(2.5)
  • Intestine(2.1)
genes like me logo Genes that share expression patterns with BSDC1: view

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for BSDC1 Gene

Orthologs for BSDC1 Gene

This gene was present in the common ancestor of animals.

Orthologs for BSDC1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia BSDC1 31 30
  • 99.22 (n)
OneToOne
dog
(Canis familiaris)
Mammalia BSDC1 31 30
  • 91.09 (n)
OneToOne
cow
(Bos Taurus)
Mammalia BSDC1 31 30
  • 90.54 (n)
OneToOne
mouse
(Mus musculus)
Mammalia Bsdc1 17 31 30
  • 89.2 (n)
rat
(Rattus norvegicus)
Mammalia Bsdc1 30
  • 88.65 (n)
oppossum
(Monodelphis domestica)
Mammalia BSDC1 31
  • 76 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia BSDC1 31
  • 74 (a)
OneToOne
chicken
(Gallus gallus)
Aves BSDC1 31 30
  • 73.43 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia BSDC1 31
  • 69 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia bsdc1 30
  • 66.5 (n)
Str.3373 30
African clawed frog
(Xenopus laevis)
Amphibia Xl.12504 30
zebrafish
(Danio rerio)
Actinopterygii bsdc1 31 30
  • 66.08 (n)
OneToOne
wufb51h12 30
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.825 30
worm
(Caenorhabditis elegans)
Secernentea Y97E10AR.6 31
  • 18 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 31
  • 41 (a)
OneToOne
Species where no ortholog for BSDC1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for BSDC1 Gene

ENSEMBL:
Gene Tree for BSDC1 (if available)
TreeFam:
Gene Tree for BSDC1 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for BSDC1: view image

Paralogs for BSDC1 Gene

Paralogs for BSDC1 Gene

genes like me logo Genes that share paralogs with BSDC1: view

Variants for BSDC1 Gene

Additional dbSNP identifiers (rs#s) for BSDC1 Gene

Structural Variations from Database of Genomic Variants (DGV) for BSDC1 Gene

Variant ID Type Subtype PubMed ID
esv7048 CNV gain 19470904

Variation tolerance for BSDC1 Gene

Residual Variation Intolerance Score: 30.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.70; 14.96% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for BSDC1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
BSDC1

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for BSDC1 Gene

Disorders for BSDC1 Gene

Additional Disease Information for BSDC1

No disorders were found for BSDC1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for BSDC1 Gene

Publications for BSDC1 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 3 4 54
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 54
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 54
  4. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark HF … Gray A (Genome research 2003) 3 4 54
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 54

Products for BSDC1 Gene

Sources for BSDC1 Gene