Aliases for BRWD3 Gene
External Ids for BRWD3 Gene
Previous GeneCards Identifiers for BRWD3 Gene
The protein encoded by this gene contains a bromodomain and several WD repeats. It is thought to have a chromatin-modifying function, and may thus play a role in transcription. Mutations in this gene are associated with a spectrum of cognitive disabilities and X-linked macrocephaly. This gene is also associated with translocations in patients with B-cell chronic lymphocytic leukemia. [provided by RefSeq, Jul 2017]
GeneCards Summary for BRWD3 Gene
BRWD3 (Bromodomain And WD Repeat Domain Containing 3) is a Protein Coding gene. Diseases associated with BRWD3 include X-Linked Nonsyndromic Deafness and Syndromic X-Linked Intellectual Disability. An important paralog of this gene is PHIP.
UniProtKB/Swiss-Prot for BRWD3 Gene
Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape.